Ten things you should know about transposable elements G Bourque, KH Burns, M Gehring, V Gorbunova, A Seluanov, M Hammell, ... Genome biology 19, 1-12, 2018 | 1258 | 2018 |
Embryonic stem cell potency fluctuates with endogenous retrovirus activity TS Macfarlan, WD Gifford, S Driscoll, K Lettieri, HM Rowe, D Bonanomi, ... Nature 487 (7405), 57-63, 2012 | 1190 | 2012 |
Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities F Li, T Macfarlan, RN Pittman, D Chakravarti Journal of Biological Chemistry 277 (47), 45004-45012, 2002 | 304 | 2002 |
Long terminal repeats: from parasitic elements to building blocks of the transcriptional regulatory repertoire PJ Thompson, TS Macfarlan, MC Lorincz Molecular cell 62 (5), 766-776, 2016 | 295 | 2016 |
Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A TS Macfarlan, WD Gifford, S Agarwal, S Driscoll, K Lettieri, J Wang, ... Genes & development 25 (6), 594-607, 2011 | 288 | 2011 |
Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition C Wang, JE Lee, B Lai, TS Macfarlan, S Xu, L Zhuang, C Liu, W Peng, ... Proceedings of the National Academy of Sciences 113 (42), 11871-11876, 2016 | 247 | 2016 |
Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation RJ Loomis, Y Naoe, JB Parker, V Savic, MR Bozovsky, T Macfarlan, ... Molecular cell 33 (4), 450-461, 2009 | 227 | 2009 |
The role of KRAB-ZFPs in transposable element repression and mammalian evolution P Yang, Y Wang, TS Macfarlan Trends in Genetics 33 (11), 871-881, 2017 | 217 | 2017 |
Transposable elements shape the evolution of mammalian development AD Senft, TS Macfarlan Nature Reviews Genetics 22 (11), 691-711, 2021 | 200 | 2021 |
The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses G Wolf, P Yang, AC Füchtbauer, EM Füchtbauer, AM Silva, C Park, W Wu, ... Genes & development 29 (5), 538-554, 2015 | 199 | 2015 |
TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells HM Rowe, A Kapopoulou, A Corsinotti, L Fasching, TS Macfarlan, ... Genome research 23 (3), 452-461, 2013 | 197 | 2013 |
Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex S Seo, T Macfarlan, P McNamara, R Hong, Y Mukai, S Heo, D Chakravarti Journal of Biological Chemistry 277 (16), 14005-14010, 2002 | 168 | 2002 |
LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control J Wang, F Telese, Y Tan, W Li, C Jin, X He, H Basnet, Q Ma, D Merkurjev, ... Nature neuroscience 18 (9), 1256-1264, 2015 | 167 | 2015 |
Transposable elements as genetic regulatory substrates in early development WD Gifford, SL Pfaff, TS Macfarlan Trends in cell biology 23 (5), 218-226, 2013 | 166 | 2013 |
Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells YJ Choi, CP Lin, D Risso, S Chen, TA Kim, MH Tan, JB Li, Y Wu, C Chen, ... Science 355 (6325), eaag1927, 2017 | 162 | 2017 |
The arms race between KRAB–zinc finger proteins and endogenous retroelements and its impact on mammals M Bruno, M Mahgoub, TS Macfarlan Annual Review of Genetics 53 (1), 393-416, 2019 | 125 | 2019 |
DUX-miR-344-ZMYM2-mediated activation of MERVL LTRs induces a totipotent 2C-like state F Yang, X Huang, R Zang, J Chen, M Fidalgo, C Sanchez-Priego, J Yang, ... Cell stem cell 26 (2), 234-250. e7, 2020 | 124 | 2020 |
Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family G Wolf, D Greenberg, TS Macfarlan Mobile Dna 6, 1-20, 2015 | 118 | 2015 |
A signaling role of histone-binding proteins and INHAT subunits pp32 and Set/TAF-Iβ in integrating chromatin hypoacetylation and transcriptional repression SN Kutney, R Hong, T Macfarlan, D Chakravarti Journal of Biological Chemistry 279 (29), 30850-30855, 2004 | 116 | 2004 |
KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage G Wolf, A de Iaco, MA Sun, M Bruno, M Tinkham, D Hoang, A Mitra, ... Elife 9, e56337, 2020 | 112 | 2020 |