Motions of allosteric and orthosteric ligand-binding sites in proteins are highly correlated X Ma, H Meng, L Lai Journal of Chemical Information and Modeling 56 (9), 1725-1733, 2016 | 79 | 2016 |
Diverse ways of perturbing the human arachidonic acid metabolic network to control inflammation H Meng, Y Liu, L Lai Accounts of chemical research 48 (8), 2242-2250, 2015 | 75 | 2015 |
Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion R Choa, J Tohyama, S Wada, H Meng, J Hu, M Okumura, RM May, ... Science 373 (6554), eabd2893, 2021 | 62 | 2021 |
Discovery of novel 15-lipoxygenase activators to shift the human arachidonic acid metabolic network toward inflammation resolution H Meng, CL McClendon, Z Dai, K Li, X Zhang, S He, E Shang, Y Liu, L Lai Journal of Medicinal Chemistry 59 (9), 4202-4209, 2016 | 62 | 2016 |
Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives X Jiang, L Zhou, D Wei, H Meng, Y Liu, L Lai Bioorganic & medicinal chemistry letters 18 (24), 6549-6552, 2008 | 36 | 2008 |
Myeloid cell hypoxia-inducible factors promote resolution of inflammation in experimental colitis N Lin, JES Shay, H Xie, DSM Lee, N Skuli, Q Tang, Z Zhou, A Azzam, ... Frontiers in immunology 9, 2565, 2018 | 35 | 2018 |
Molecular mechanism of 15-lipoxygenase allosteric activation and inhibition H Meng, Z Dai, W Zhang, Y Liu, L Lai Physical Chemistry Chemical Physics 20 (21), 14785-14795, 2018 | 31 | 2018 |
Sexual dimorphism in the response to chronic circadian misalignment on a high-fat diet ST Anderson, H Meng, TG Brooks, SY Tang, R Lordan, A Sengupta, ... Science Translational Medicine 15 (696), eabo2022, 2023 | 25 | 2023 |
Genomic and lipidomic analyses differentiate the compensatory roles of two COX isoforms during systemic inflammation in mice 1, 2 [S] X Li, LL Mazaleuskaya, LL Ballantyne, H Meng, GA FitzGerald, CD Funk Journal of lipid research 59 (1), 102-112, 2018 | 24 | 2018 |
Deep phenotyping of the lipidomic response in COVID‐19 and non‐COVID‐19 sepsis H Meng, A Sengupta, E Ricciotti, A Mrčela, D Mathew, LL Mazaleuskaya, ... Clinical and Translational Medicine 13 (11), e1440, 2023 | 17 | 2023 |
Cyclooxygenase-2, asymmetric dimethylarginine, and the cardiovascular hazard from nonsteroidal anti-inflammatory drugs E Ricciotti, C Castro, SY Tang, WTE Briggs, JA West, D Malik, ... Circulation 138 (21), 2367-2378, 2018 | 15 | 2018 |
A novel allosteric inhibitor that prevents IKKβ activation H Liu, H Liang, H Meng, X Deng, X Zhang, L Lai Medchemcomm 9 (2), 239-243, 2018 | 15 | 2018 |
Flipping the cyclooxygenase (Ptgs) genes reveals isoform-specific compensatory functions 1, 2 [S] X Li, LL Mazaleuskaya, C Yuan, LL Ballantyne, H Meng, WL Smith, ... Journal of Lipid Research 59 (1), 89-101, 2018 | 15 | 2018 |
Considerations for the safe operation of schools during the coronavirus pandemic R Lordan, S Prior, E Hennessy, A Naik, S Ghosh, GK Paschos, C Skarke, ... Frontiers in public health 9, 751451, 2021 | 14 | 2021 |
Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase H Meng, Y Liu, Y Zhai, L Lai European Journal of Medicinal Chemistry 59, 160-167, 2013 | 13 | 2013 |
Identification of 1, 4‐Dihydrothieno [3′, 2′: 5, 6] thiopyrano [4, 3‐c] pyrazole Derivatives as Human 5‐Lipo‐oxygenase Inhibitors J Hu, W Zhu, H Meng, Y Liu, X Wang, C Hu Chemical Biology & Drug Design 84 (6), 642-647, 2014 | 7 | 2014 |
Nonsteroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal hematodiaphyseal dysplasia TJ Brown, N Barrett, H Meng, E Ricciotti, C McDonnell, A Dancis, ... Blood 141 (13), 1553-1559, 2023 | 6 | 2023 |
Differential compensation of two cyclooxygenases in renal homeostasis is independent of prostaglandin-synthetic capacity under basal conditions X Li, LL Mazaleuskaya, LL Ballantyne, H Meng, GA FitzGerald, CD Funk The FASEB Journal 32 (10), 5326, 2018 | 5 | 2018 |
Differential Impact In Vivo of Pf4-ΔCre–Mediated and Gp1ba-ΔCre–Mediated Depletion of Cyclooxygenase-1 in Platelets in Mice SY Tang, R Lordan, H Meng, BJ Auerbach, EJ Hennessy, A Sengupta, ... Arteriosclerosis, thrombosis, and vascular biology 44 (6), 1393-1406, 2024 | 4 | 2024 |
Modulation of the immune response to severe acute respiratory syndrome coronavirus 2 vaccination by nonsteroidal anti-inflammatory drugs C Skarke, R Lordan, K Barekat, A Naik, D Mathew, T Ohtani, ... Journal of Pharmacology and Experimental Therapeutics 386 (2), 198-204, 2023 | 3 | 2023 |