Towards a comprehensive characterisation of the human internal chemical exposome: Challenges and perspectives A David, J Chaker, EJ Price, V Bessonneau, AJ Chetwynd, CM Vitale, ... Environment International 156, 106630, 2021 | 62 | 2021 |
CGRP-dependent signalling pathways involved in mouse models of GTN-cilostazol-and levcromakalim-induced migraine SL Christensen, RH Rasmussen, C Ernstsen, S La Cour, A David, ... Cephalalgia 41 (14), 1413-1426, 2021 | 42 | 2021 |
From metabolomics to HRMS-based exposomics: adapting peak picking and developing scoring for MS1 suspect screening J Chaker, E Gilles, T Léger, B Jégou, A David Analytical Chemistry 93 (3), 1792-1800, 2020 | 32 | 2020 |
Acetaminophen metabolism revisited using non-targeted analyses: Implications for human biomonitoring A David, J Chaker, T Léger, R Al-Salhi, MD Dalgaard, B Styrishave, ... Environment International 149, 106388, 2021 | 27 | 2021 |
Assessing the contribution of the chemical exposome to neurodegenerative disease S Lefevre-Arbogast, J Chaker, F Mercier, R Barouki, X Coumoul, ... Nature Neuroscience, 1-10, 2024 | 23 | 2024 |
Comprehensive evaluation of blood plasma and serum sample preparations for HRMS-based chemical exposomics: overlaps and specificities J Chaker, DM Kristensen, TI Halldorsson, SF Olsen, C Monfort, C Chevrier, ... Analytical Chemistry 94 (2), 866-874, 2022 | 18 | 2022 |
Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism A Rehfeld, H Frederiksen, RH Rasmussen, A David, J Chaker, BS Nielsen, ... Human Reproduction 37 (5), 922-935, 2022 | 11 | 2022 |
Improving Exposure Assessment Using Non-Targeted and Suspect Screening: The ISO/IEC 17025: 2017 Quality Standard as a Guideline J Monteiro Bastos da Silva, J Chaker, A Martail, J Costa Moreira, A David, ... Journal of Xenobiotics 11 (1), 1-15, 2021 | 11 | 2021 |
Harmonized quality assurance/quality control provisions to assess completeness and robustness of MS1 data preprocessing for LC-HRMS-based suspect screening and non-targeted … S Lennon, J Chaker, EJ Price, J Hollender, C Huber, T Schulze, L Ahrens, ... TrAC Trends in Analytical Chemistry, 117674, 2024 | 9 | 2024 |
Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment Ž Tkalec, JP Antignac, N Bandow, FM Béen, L Belova, J Bessems, ... Environment international 186, 108585, 2024 | 5 | 2024 |
What is in the fish? Collaborative trial in suspect and non-target screening of organic micropollutants using LC-and GC-HRMS W Dürig, S Lindblad, O Golovko, G Gkotsis, R Aalizadeh, MC Nika, ... Environment international 181, 108288, 2023 | 5 | 2023 |
Scannotation: A Suspect Screening Tool for the Rapid Pre-Annotation of the Human LC-HRMS-Based Chemical Exposome J Chaker, E Gilles, C Monfort, C Chevrier, S Lennon, A David Environmental Science & Technology 57 (48), 19253-19262, 2023 | 4 | 2023 |
Paracetamol/acetaminophen hepatotoxicity: new markers for monitoring the elimination of the reactive N-Acetyl-p-benzoquinone imine E Gorrochategui, ML Vee, H Selmi, A Gérard, J Chaker, AM Krais, C Lindh, ... bioRxiv, 2023.04. 28.538718, 2023 | 4 | 2023 |
High-resolution mass spectrometry identifies delayed biomarkers for improved precision in acetaminophen/paracetamol human biomonitoring E Gorrochategui, M Le Vee, H Selmi, A Gérard, J Chaker, AM Krais, ... Environment International 181, 108299, 2023 | 2 | 2023 |
Exposome chimique et approches «non ciblées»-Un changement de paradigme pour évaluer l’exposition des populations aux contaminants chimiques A David, J Chaker, L Multigner, V Bessonneau médecine/sciences 37 (10), 895-901, 2021 | 2 | 2021 |
Chemical exposome and non-targeted approaches A David, J Chaker, L Multigner, V Bessonneau Medecine Sciences: M/S 37 (10), 895-901, 2021 | 1 | 2021 |
Research gaps and unmet challenges to study the impact of chemicals on neurodegenerative diseases C Samieri, S Lefèvre‐Arbogast, J Chaker, F Mercier, R Barouki, ... Alzheimer's & Dementia 20, e087446, 2024 | | 2024 |
Current epidemiological and experimental evidence relating the chemical exposome to Alzheimer’s disease S Lefèvre‐Arbogast, J Chaker, F Mercier, R Barouki, X Coumoul, ... Alzheimer's & Dementia 20, e087443, 2024 | | 2024 |
The exposome concept in the context of Alzheimer’s disease C Samieri, S Lefèvre-Arbogast, J Chaker, F Mercier, R Barouki, ... Alzheimer's Association International Conference, 2024 | | 2024 |
Peut-on améliorer le diagnostic et le suivi des patients intoxiqués à l’aide de nouveaux biomarqueurs thiomethylés du paracétamol? T Gicquel, E Gorrochategui, R Pelletier, H Margaux, J Chaker, I Morel, ... Toxicologie Analytique et Clinique 36 (2), S42-S43, 2024 | | 2024 |