The cell biology of polycystic kidney disease HC Chapin, MJ Caplan Journal of Cell Biology 191 (4), 701-710, 2010 | 334 | 2010 |
Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases YH Choi, A Suzuki, S Hajarnis, Z Ma, HC Chapin, MJ Caplan, M Pontoglio, ... Proceedings of the National Academy of Sciences 108 (26), 10679-10684, 2011 | 150 | 2011 |
Tissue-specific autophagy responses to aging and stress in C. elegans HC Chapin, M Okada, AJ Merz, DL Miller Aging (Albany NY) 7 (6), 419, 2015 | 96 | 2015 |
Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site HC Chapin, V Rajendran, MJ Caplan Molecular biology of the cell 21 (24), 4338-4348, 2010 | 89 | 2010 |
The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function V Padovano, IY Kuo, LK Stavola, HR Aerni, BJ Flaherty, HC Chapin, M Ma, ... Molecular biology of the cell 28 (2), 261-269, 2017 | 88 | 2017 |
The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism D Merrick, H Chapin, JE Baggs, Z Yu, S Somlo, Z Sun, JB Hogenesch, ... Developmental cell 22 (1), 197-210, 2012 | 79 | 2012 |
Termination of isoform‐selective Vps21/Rab5 signaling at endolysosomal organelles by Msb3/Gyp3 DP Nickerson, MRG Russell, SY Lo, HC Chapin, JM Milnes, AJ Merz Traffic 13 (10), 1411-1428, 2012 | 62 | 2012 |
Polycystin-1 C-terminal cleavage is modulated by polycystin-2 expression CA Bertuccio, HC Chapin, Y Cai, K Mistry, V Chauvet, S Somlo, ... Journal of Biological Chemistry 284 (31), 21011-21026, 2009 | 49 | 2009 |
Undergraduate science learners show comparable outcomes whether taught by undergraduate or graduate teaching assistants HC Chapin, BL Wiggins, LE Martin-Morris Journal of college science teaching 44 (2), 90-99, 2014 | 43 | 2014 |
Polycystin-1 cleavage and the regulation of transcriptional pathways D Merrick, CA Bertuccio, HC Chapin, M Lal, V Chauvet, MJ Caplan Pediatric Nephrology 29, 505-511, 2014 | 37 | 2014 |
Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression S Bian, JP Bai, H Chapin, C Le Moellic, H Dong, M Caplan, FJ Sigworth, ... PLoS One 6 (12), e28264, 2011 | 22 | 2011 |
Newly synthesized polycystin‐1 takes different trafficking pathways to the apical and ciliary membranes AL Gilder, HC Chapin, V Padovano, CL Hueschen, V Rajendran, ... Traffic 19 (12), 933-945, 2018 | 13 | 2018 |
Detecting the surface localization and cytoplasmic cleavage of membrane-bound proteins HC Chapin, V Rajendran, A Capasso, MJ Caplan Methods in cell biology 94, 223-239, 2009 | 10 | 2009 |
Msb3/Gyp3 GAP selectively opposes Rab5 signaling at endolysosomal organelles DP Nickerson, MRG Russell, SY Lo, HC Chapin, J Milnes, AJ Merz Traffic (Copenhagen, Denmark) 13 (10), 1411, 2012 | 2 | 2012 |
Regulation of the polycystin trafficking and ion channel activity by oxygen levels V Padovano, HR Aerni, IY Kuo, BJ Flaherty, LK Stavola, HC Chapin, M Ma, ... MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
Role of Calcineurin in Polycystin Protein Trafficking to the Primary Cilium in LLCPK Cells AL Gilder, HC Chapin, MJ Caplan The FASEB Journal 26, 868.3-868.3, 2012 | | 2012 |
Cleavage and trafficking of polycystin-1 HC Chapin Yale University, 2010 | | 2010 |
Cleavage of Membrane-Bound Proteins 11. Detecting the Surface Localization and Cytoplasmic I. Introduction HC Chapin, V Rajendran, A Capasso, MJ Caplan Methods in Cell Biology 94, 224, 2009 | | 2009 |
RESEARCH AND TEACHING AJ Remsburg, MA Harris, JM Batzli, PA Jensen, JN Barron, HC Chapin, ... | | |