Intercellular nanotubes mediate mitochondrial trafficking between cancer and immune cells T Saha, C Dash, R Jayabalan, S Khiste, A Kulkarni, K Kurmi, J Mondal, ... Nature nanotechnology 17 (1), 98-106, 2022 | 234 | 2022 |
Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function G Notarangelo, JB Spinelli, EM Perez, GJ Baker, K Kurmi, I Elia, ... Science 377 (6614), 1519-1529, 2022 | 185 | 2022 |
Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells I Elia, JH Rowe, S Johnson, S Joshi, G Notarangelo, K Kurmi, S Weiss, ... Cell metabolism 34 (8), 1137-1150. e6, 2022 | 171 | 2022 |
Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells JM Drijvers, JE Gillis, T Muijlwijk, TH Nguyen, EF Gaudiano, IS Harris, ... Cancer immunology research 9 (2), 184-199, 2021 | 127 | 2021 |
Carnitine palmitoyltransferase 1A has a lysine succinyltransferase activity K Kurmi, S Hitosugi, EK Wiese, F Boakye-Agyeman, WI Gonsalves, Z Lou, ... Cell reports 22 (6), 1365-1373, 2018 | 119 | 2018 |
Nitrogen metabolism in cancer and immunity K Kurmi, MC Haigis Trends in Cell Biology 30 (5), 408-424, 2020 | 118 | 2020 |
Tyrosine phosphorylation of mitochondrial creatine kinase 1 enhances a druggable tumor energy shuttle pathway K Kurmi, S Hitosugi, J Yu, F Boakye-Agyeman, EK Wiese, TR Larson, ... Cell metabolism 28 (6), 833-847. e8, 2018 | 72 | 2018 |
BRCA1 deficiency upregulates NNMT, which reprograms metabolism and sensitizes ovarian cancer cells to mitochondrial metabolic targeting agents A Kanakkanthara, K Kurmi, TL Ekstrom, X Hou, ER Purfeerst, EP Heinzen, ... Cancer research 79 (23), 5920-5929, 2019 | 63 | 2019 |
Enzymatic activation of pyruvate kinase increases cytosolic oxaloacetate to inhibit the Warburg effect EK Wiese, S Hitosugi, ST Loa, A Sreedhar, LG Andres-Beck, K Kurmi, ... Nature metabolism 3 (7), 954-968, 2021 | 44 | 2021 |
Circulating Mycobacterium bovis peptides and host response proteins as biomarkers for unambiguous detection of subclinical infection EA Lamont, HK Janagama, J Ribeiro-Lima, L Vulchanova, M Seth, ... Journal of clinical microbiology 52 (2), 536-543, 2014 | 42 | 2014 |
Impaired β-cell glucokinase as an underlying mechanism in diet-induced diabetes B Lu, K Kurmi, M Munoz-Gomez, EJ Jacobus Ambuludi, JM Tonne, ... Disease models & mechanisms 11 (6), dmm033316, 2018 | 29 | 2018 |
Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis CH Yao, JS Park, K Kurmi, SH Hu, G Notarangelo, J Crowley, H Jacobson, ... Molecular cell 83 (8), 1340-1349. e7, 2023 | 17 | 2023 |
Metabolic modulation of mitochondrial mass during CD4+ T cell activation K Kurmi, D Liang, R van de Ven, P Georgiev, BM Gassaway, SJ Han, ... Cell chemical biology 30 (9), 1064-1075. e8, 2023 | 4 | 2023 |
Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing T Ogawa, M Isik, Z Wu, K Kurmi, J Meng, S Cho, G Lee, ... Molecular Cell 84 (23), 4558-4575. e8, 2024 | 1 | 2024 |
GUK1 is a novel metabolic liability in oncogene-driven lung cancer JL Schneider, K Kurmi, I Dhiman, R Colapietro, S Joshi, C Johnson, ... Cancer Research 83 (7_Supplement), 1156-1156, 2023 | 1 | 2023 |
GUK1 activation is a metabolic liability in lung cancer JL Schneider, K Kurmi, Y Dai, I Dhiman, S Joshi, BM Gassaway, ... Cell, 2025 | | 2025 |
825 Targeting lipid metabolism to improve PARP inhibitor response in BRCA-associated TNBC CWS Wanderley, DE Michaud, K Kurmi, K Shimada, A Nelson, KF Zheng, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
Profiling Proteins and Phosphorylation Sites During T Cell Activation Using an Integrated Thermal Shift Assay BM Gassaway, EL Huttlin, EM Huntsman, TM Yaron-Barir, JL Johnson, ... Molecular & Cellular Proteomics 23 (7), 100801, 2024 | | 2024 |
Targeting glutamine metabolism mitigates Foxp3-deficiency mediated disease LM Charbonnier, C Hill, Y Zhong, S Josh, Y El Fazaa, P Georgiev, ... The Journal of Immunology 212 (1_Supplement), 1445_4269-1445_4269, 2024 | | 2024 |
Multiomics analysis unravels tumor metabolic reprogramming and potential resistance mechanism (s) to curative therapy in TNBC Z Ren, K Kurmi, R Morris, S Joshi, E Zaniewski, J Kreuzer, GE Gioia, ... Cancer Research 84 (6_Supplement), 5850-5850, 2024 | | 2024 |