Capsaicin, a novel inhibitor of the NorA efflux pump, reduces the intracellular invasion of Staphylococcus aureus NP Kalia, P Mahajan, R Mehra, A Nargotra, JP Sharma, S Koul, IA Khan Journal of antimicrobial chemotherapy 67 (10), 2401-2408, 2012 | 234 | 2012 |
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection NP Kalia, EJ Hasenoehrl, NB Ab Rahman, VH Koh, MLT Ang, DR Sajorda, ... Proceedings of the National Academy of Sciences 114 (28), 7426-7431, 2017 | 208 | 2017 |
Sulfur rich 2-mercaptobenzothiazole and 1, 2, 3-triazole conjugates as novel antitubercular agents F Mir, S Shafi, MS Zaman, NP Kalia, VS Rajput, C Mulakayala, ... European Journal of Medicinal Chemistry 76, 274-283, 2014 | 128 | 2014 |
Piperine analogs as potent Staphylococcus aureus NorA efflux pump inhibitors PL Sangwan, JL Koul, S Koul, MV Reddy, N Thota, IA Khan, A Kumar, ... Bioorganic & medicinal chemistry 16 (22), 9847-9857, 2008 | 123 | 2008 |
Protective efficacy of piperine against Mycobacterium tuberculosis S Sharma, NP Kalia, P Suden, PS Chauhan, M Kumar, AB Ram, ... Tuberculosis 94 (4), 389-396, 2014 | 97 | 2014 |
Piperine as an inhibitor of the MdeA efflux pump of Staphylococcus aureus ZM Mirza, A Kumar, NP Kalia, A Zargar, IA Khan Journal of medical microbiology 60 (10), 1472-1478, 2011 | 97 | 2011 |
Antimicrobial and Antimycobacterial Activities of Methyl Caffeate Isolated from Solanum torvum Swartz. Fruit C Balachandran, V Duraipandiyan, NA Al-Dhabi, K Balakrishna, NP Kalia, ... Indian Journal of Microbiology 52, 676-681, 2012 | 91 | 2012 |
Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis BS Lee, K Hards, CA Engelhart, EJ Hasenoehrl, NP Kalia, JS Mackenzie, ... EMBO molecular medicine 13 (1), e13207, 2021 | 81 | 2021 |
Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer N Scherr, R Bieri, SS Thomas, A Chauffour, NP Kalia, P Schneide, MT Ruf, ... Nature communications 9 (1), 5370, 2018 | 75 | 2018 |
Boeravinone B, A Novel Dual Inhibitor of NorA Bacterial Efflux Pump of Staphylococcus aureus and Human P-Glycoprotein, Reduces the Biofilm Formation and … S Singh, NP Kalia, P Joshi, A Kumar, PR Sharma, A Kumar, SB Bharate, ... Frontiers in microbiology 8, 1868, 2017 | 75 | 2017 |
Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria BS Lee, NP Kalia, XEF Jin, EJ Hasenoehrl, M Berney, K Pethe Journal of Biological Chemistry 294 (6), 1936-1943, 2019 | 61 | 2019 |
Discovery of a novel mycobacterial F‐ATP synthase inhibitor and its potency in combination with diarylquinolines A Hotra, P Ragunathan, PS Ng, P Seankongsuk, A Harikishore, ... Angewandte Chemie International Edition 59 (32), 13295-13304, 2020 | 50 | 2020 |
Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc1:aa3 in Mycobacterium tuberculosis NP Kalia, B Shi Lee, NB Ab Rahman, GC Moraski, MJ Miller, K Pethe Scientific reports 9 (1), 8608, 2019 | 42 | 2019 |
Synthesis of new generation triazolyl-and isoxazolyl-containing 6-nitro-2, 3-dihydroimidazooxazoles as anti-TB agents: in vitro, structure–activity relationship … G Munagala, KR Yempalla, S Singh, S Sharma, NP Kalia, VS Rajput, ... Organic & Biomolecular Chemistry 13 (12), 3610-3624, 2015 | 40 | 2015 |
Substituted dihydronaphthalenes as efflux pump inhibitors of Staphylococcus aureus N Thota, MV Reddy, A Kumar, IA Khan, PL Sangwan, NP Kalia, JL Koul, ... European journal of medicinal chemistry 45 (9), 3607-3616, 2010 | 34 | 2010 |
Anti-tubercular agents. Part 7: A new class of diarylpyrrole–oxazolidinone conjugates as antimycobacterial agents A Kamal, P Swapna, RV Shetti, AB Shaik, MPN Rao, F Sultana, IA Khan, ... European journal of medicinal chemistry 64, 239-251, 2013 | 28 | 2013 |
Target engagement and binding mode of an antituberculosis drug to its bacterial target deciphered in whole living cells by NMR G Bouvier, C Simenel, J Jang, NP Kalia, I Choi, M Nilges, K Pethe, ... Biochemistry 58 (6), 526-533, 2018 | 27 | 2018 |
Toward a single-dose cure for Buruli ulcer SS Thomas, NP Kalia, MT Ruf, G Pluschke, K Pethe Antimicrobial agents and chemotherapy 64 (9), 10.1128/aac. 00727-20, 2020 | 24 | 2020 |
Structure guided generation of thieno [3, 2-d] pyrimidin-4-amine Mycobacterium tuberculosis bd oxidase inhibitors SM Hopfner, BS Lee, NP Kalia, MJ Miller, K Pethe, GC Moraski RSC Medicinal Chemistry 12 (1), 73-77, 2021 | 23 | 2021 |
M. tuberculosis relies on trace oxygen to maintain energy homeostasis and survive in hypoxic environments NP Kalia, S Singh, K Hards, CY Cheung, E Sviriaeva, A Banaei-Esfahani, ... Cell Reports 42 (5), 2023 | 18 | 2023 |