Small heat shock proteins in neurodegenerative diseases L Vendredy, E Adriaenssens, V Timmerman Cell Stress and Chaperones 25 (4), 679-699, 2020 | 94 | 2020 |
Axonal neuropathies due to mutations in small heat shock proteins: clinical, genetic, and functional insights into novel mutations A Echaniz‐Laguna, T Geuens, P Petiot, Y Péréon, E Adriaenssens, ... Human Mutation 38 (5), 556-568, 2017 | 81 | 2017 |
Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies M Haidar, B Asselbergh, E Adriaenssens, V De Winter, JP Timmermans, ... Autophagy 15 (6), 1051-1068, 2019 | 77 | 2019 |
Orchestration of selective autophagy by cargo receptors E Adriaenssens, L Ferrari, S Martens Current Biology 32 (24), R1357-R1371, 2022 | 75 | 2022 |
Molecular chaperones in the pathogenesis of amyotrophic lateral sclerosis: the role of HSPB1 S Capponi, T Geuens, A Geroldi, P Origone, S Verdiani, E Cichero, ... Human mutation 37 (11), 1202-1208, 2016 | 61 | 2016 |
Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish A Siekierska, H Stamberger, T Deconinck, SN Oprescu, M Partoens, ... Nature communications 10 (1), 708, 2019 | 56 | 2019 |
Unconventional initiation of PINK1/Parkin mitophagy by optineurin TN Nguyen, J Sawa-Makarska, G Khuu, WK Lam, E Adriaenssens, ... Molecular Cell 83 (10), 1693-1709. e9, 2023 | 55 | 2023 |
Partial inhibition of glycolysis reduces atherogenesis independent of intraplaque neovascularization in mice P Perrotta, B Van der Veken, P Van Der Veken, I Pintelon, L Roosens, ... Arteriosclerosis, thrombosis, and vascular biology 40 (5), 1168-1181, 2020 | 48 | 2020 |
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space E Adriaenssens, B Asselbergh, P Rivera-Mejías, S Bervoets, L Vendredy, ... Nature Cell Biology 25 (3), 467-480, 2023 | 47 | 2023 |
BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes E Adriaenssens, B Tedesco, L Mediani, B Asselbergh, V Crippa, ... Scientific Reports 10 (1), 8755, 2020 | 47 | 2020 |
Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction J Van Lent, P Verstraelen, B Asselbergh, E Adriaenssens, L Mateiu, ... Brain 144 (8), 2471-2485, 2021 | 42 | 2021 |
Novel insights in the disease biology of mutant small heat shock proteins in neuromuscular diseases E Adriaenssens, T Geuens, J Baets, A Echaniz-Laguna, V Timmerman Brain 140 (10), 2541-2549, 2017 | 42 | 2017 |
NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy T Kataura, EG Otten, Y Rabanal‐Ruiz, E Adriaenssens, F Urselli, F Scialo, ... The EMBO Journal 42 (5), e111372, 2023 | 32 | 2023 |
A weakened interface in the P182L variant of HSP27 associated with severe Charcot‐Marie‐Tooth neuropathy causes aberrant binding to interacting proteins T Reid Alderson, E Adriaenssens, B Asselbergh, I Pritišanac, J Van Lent, ... The EMBO Journal 40 (8), e103811, 2021 | 21 | 2021 |
Downregulation of PMP22 ameliorates myelin defects in iPSC-derived human organoid cultures of CMT1A J Van Lent, L Vendredy, E Adriaenssens, T Da Silva Authier, ... Brain 146 (7), 2885-2896, 2023 | 17 | 2023 |
HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies B Tedesco, L Vendredy, E Adriaenssens, M Cozzi, B Asselbergh, ... Autophagy 19 (8), 2217-2239, 2023 | 15 | 2023 |
Mechanistic convergence and shared therapeutic targets in Niemann‐Pick disease A Colaco, E Kaya, E Adriaenssens, LC Davis, S Zampieri, ... Journal of Inherited Metabolic Disease 43 (3), 574-585, 2020 | 15 | 2020 |
Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD E Adriaenssens, TN Nguyen, J Sawa-Makarska, G Khuu, M Schuschnig, ... Nature Structural & Molecular Biology 31 (11), 1717-1731, 2024 | 7 | 2024 |
Dysregulated interactions triggered by a neuropathy-causing mutation in the IPV motif of HSP27 TR Alderson, E Adriaenssens, B Asselbergh, I Pritišanac, HY Gastall, ... BioRxiv, 708180, 2019 | 4 | 2019 |
IPSC-DERIVED MOTOR NEURONS REVEAL PROGRESSIVE MITOCHONDRIAL DYSFUNCTION IN AXONAL CMT SUBTYPES J Van Lent, P Verstraelen, B Asselbergh, E Adriaenssens, L Mateiu, ... JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM 27, S137-S137, 2022 | | 2022 |