CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells J Kim, Z Hu, L Cai, K Li, E Choi, B Faubert, D Bezwada, ... Nature 546 (7656), 168-172, 2017 | 291 | 2017 |
Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex E Uchikawa, E Choi*, G Shang, H Yu*, X Bai* elife 8, e48630, 2019 | 168 | 2019 |
Structural basis of the activation of type 1 insulin-like growth factor receptor J Li, E Choi*, H Yu*, X Bai* Nature communications 10 (4567), 2019 | 159 | 2019 |
BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis E Choi, H Choe, J Min, JY Choi, J Kim, H Lee The EMBO journal 28 (14), 2077-2089, 2009 | 147 | 2009 |
Insulin receptor endocytosis in the pathophysiology of insulin resistance C Hall, H Yu*, E Choi* Experimental & Molecular Medicine, 2020 | 134 | 2020 |
Mitotic checkpoint regulators control insulin signaling and metabolic homeostasis E Choi, X Zhang, C Xing, H Yu Cell 166, 1-15, 2016 | 114 | 2016 |
Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling E Choi, S Kikuchi, H Gao, K Brodzik, I Nassour, A Yopp, AG Singel, H Zhu, ... Nature communications 10 (1473), 2019 | 99 | 2019 |
BRCA2 fine-tunes the spindle assembly checkpoint through reinforcement of BubR1 acetylation E Choi, PG Park, H Lee, YK Lee, GH Kang, JW Lee, W Han, HC Lee, ... Developmental cell 22 (2), 295-308, 2012 | 96 | 2012 |
BubR1 as a prognostic marker for recurrence-free survival rates in epithelial ovarian cancers YK Lee, E Choi, MA Kim, PG Park, NH Park, H Lee British journal of cancer 101 (3), 504-510, 2009 | 64 | 2009 |
Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation I Park, H Lee, E Choi, YK Lee, MS Kwon, J Min, PG Park, S Lee, YY Kong, ... Journal of Cell Biology 202 (2), 295-309, 2013 | 57 | 2013 |
Synergistic activation of the insulin receptor via two distinct sites J Li, J Park, JP Mayer, KJ Webb, E Uchikawa, J Wu, S Liu, X Zhang, ... Nature Structural & Molecular Biology, 1-12, 2022 | 48 | 2022 |
A dominant negative form of p63 inhibits apoptosis in a p53-independent manner H Lee, JH Lee, E Choi, JY Seol, Y Yun, H Lee Biochemical and biophysical research communications 344 (1), 166-172, 2006 | 44 | 2006 |
Inhibition of Plk1 induces mitotic infidelity and embryonic growth defects in developing zebrafish embryos KH Jeong, JY Jeong, HO Lee, E Choi, H Lee Developmental biology 345 (1), 34-48, 2010 | 38 | 2010 |
The Activation Mechanism of the Insulin Receptor: A Structural Perspective E Choi*, X Bai* Annual Review of Biochemistry 92, 2023 | 34 | 2023 |
Chromosome damage in mitosis induces BubR1 activation and prometaphase arrest E Choi, H Lee FEBS letters 582 (12), 1700-1706, 2008 | 24 | 2008 |
Activation of the insulin receptor by an insulin mimetic peptide J Park, J Li, JP Mayer, KA Ball, J Wu, C Hall, D Accili, MHB Stowell, X Bai, ... Nature communications 13 (1), 5594, 2022 | 22 | 2022 |
Structural basis of insulin fibrillation L Wang#, CE Hall#, E Uchikawa, D Chen, E Choi*, X Zhang*, X Bai* Science Advances 9 (37), eadi1057, 2023 | 16 | 2023 |
HDAC 2/3 binding and deacetylation of BubR1 initiates spindle assembly checkpoint silencing I Park, MS Kwon, S Paik, H Kim, HO Lee, E Choi, H Lee The FEBS Journal 284 (23), 4035-4050, 2017 | 15 | 2017 |
Identification of Rad51 regulation by BRCA2 using Caenorhabditis elegans BRCA2 and bimolecular fluorescence complementation analysis J Min, P Park, E Ko, E Choi, H Lee Biochemical and biophysical research communications 362 (4), 958-964, 2007 | 13 | 2007 |
Spindle checkpoint regulators in insulin signaling E Choi, H Yu Frontiers in Cell and Developmental Biology 6, 161, 2018 | 12 | 2018 |