Myelination and mTOR G Figlia, D Gerber, U Suter Glia 66 (4), 693-707, 2018 | 153 | 2018 |
mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells C Norrmen, G Figlia, F Lebrun-Julien, JA Pereira, M Trötzmüller, ... Cell reports 9 (2), 646-660, 2014 | 136 | 2014 |
Cdk4 and Cdk6 couple the cell-cycle machinery to cell growth via mTORC1 J Romero-Pozuelo, G Figlia, O Kaya, A Martin-Villalba, AA Teleman Cell reports 31 (2), 2020 | 130 | 2020 |
Metabolites regulate cell signaling and growth via covalent modification of proteins G Figlia, P Willnow, AA Teleman Developmental cell 54 (2), 156-170, 2020 | 116 | 2020 |
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling MT Prentzell, U Rehbein, MC Sandoval, AS De Meulemeester, ... Cell 184 (3), 655-674. e27, 2021 | 106 | 2021 |
Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system G Figlia, C Norrmen, JA Pereira, D Gerber, U Suter Elife 6, e29241, 2017 | 96 | 2017 |
Non-redundant function of dystroglycan and β1 integrins in radial sorting of axons C Berti, L Bartesaghi, M Ghidinelli, D Zambroni, G Figlia, ZL Chen, ... Development 138 (18), 4025-4037, 2011 | 75 | 2011 |
De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination L Montani, JA Pereira, C Norrmén, HBF Pohl, E Tinelli, M Trötzmüller, ... Journal of Cell Biology 217 (4), 1353-1368, 2018 | 70 | 2018 |
mTORC1 is transiently reactivated in injured nerves to promote c-Jun elevation and Schwann cell dedifferentiation C Norrmén, G Figlia, P Pfistner, JA Pereira, S Bachofner, U Suter Journal of Neuroscience 38 (20), 4811-4828, 2018 | 63 | 2018 |
MMP2-9 cleavage of dystroglycan alters the size and molecular composition of Schwann cell domains D Zambroni, E Pavoni, C Colombelli, C Baragli, G Figlia, L Sorokin, ... Journal of Neuroscience 31 (34), 12208-12217, 2011 | 38 | 2011 |
Schwann cells, but not oligodendrocytes, depend strictly on dynamin 2 function D Gerber, M Ghidinelli, E Tinelli, C Somandin, J Gerber, JA Pereira, ... Elife 8, e42404, 2019 | 32 | 2019 |
Practice of yoga may cause damage of both sciatic nerves: a case report P Dacci, S Amadio, S Gerevini, L Moiola, U Del Carro, M Radaelli, ... Neurological Sciences 34, 393-396, 2013 | 27 | 2013 |
Synthesis and Preliminary Evaluation in Tumor Bearing Mice of New 18F-Labeled Arylsulfone Matrix Metalloproteinase Inhibitors as Tracers for Positron Emission … F Casalini, L Fugazza, G Esposito, C Cabella, C Brioschi, A Cordaro, ... Journal of Medicinal Chemistry 56 (6), 2676-2689, 2013 | 23 | 2013 |
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor R Nicastro, L Brohée, J Alba, J Nüchel, G Figlia, S Kipschull, P Gollwitzer, ... Nature Cell Biology 25 (9), 1303-1318, 2023 | 22 | 2023 |
Interferon regulates neural stem cell function at all ages by orchestrating mTOR and cell cycle D Carvajal Ibañez, M Skabkin, J Hooli, S Cerrizuela, M Göpferich, A Jolly, ... EMBO Molecular Medicine 15 (4), e16434, 2023 | 22 | 2023 |
Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition G Figlia, S Müller, AM Hagenston, S Kleber, M Roiuk, JP Quast, ... Nature cell biology 24 (9), 1407-1421, 2022 | 21 | 2022 |
Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system A Ommer, G Figlia, JA Pereira, AL Datwyler, J Gerber, J DeGeer, G Lalli, ... Journal of Cell Biology 218 (7), 2350-2369, 2019 | 21 | 2019 |
C-Jun in Schwann cells: stay away from extremes G Figlia The Journal of Neuroscience 38 (14), 3388, 2018 | 12 | 2018 |
Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor R Nicastro, L Brohée, J Alba, J Nüchel, G Figlia, S Kipschull, P Gollwitzer, ... bioRxiv, 2022.11. 06.515351, 2022 | | 2022 |
G3BP1 tethers the TSC complex to lysosomes and suppresses mTORC1 in the absence of stress granules MT Prentzell, U Rehbein, MC Sandoval, AS De Meulemeester, ... bioRxiv, 2020.04. 16.044081, 2020 | | 2020 |