| Bacterial Metabolism and Antibiotic Efficacy JM Stokes, AJ Lopatkin, MA Lobritz, JJ Collins Cell Metabolism, 2019 | 510 | 2019 |
| Persistence and reversal of plasmid-mediated antibiotic resistance AJ Lopatkin, HR Meredith, JK Srimani, C Pfeiffer, R Durrett, L You Nature communications 8 (1), 1689, 2017 | 338 | 2017 |
| A white-box machine learning approach for revealing antibiotic mechanisms of action JH Yang, SN Wright, M Hamblin, D McCloskey, MA Alcantar, ... Cell 177 (6), 1649-1661. e9, 2019 | 305 | 2019 |
| Antibiotics as a selective driver for conjugation dynamics AJ Lopatkin, S Huang, RP Smith, JK Srimani, TA Sysoeva, S Bewick, ... Nature microbiology 1 (6), 1-8, 2016 | 298 | 2016 |
| Clinically relevant mutations in core metabolic genes confer antibiotic resistance AJ Lopatkin, SC Bening, AL Manson, JM Stokes, MA Kohanski, ... Science 371 (6531), eaba0862, 2021 | 286 | 2021 |
| Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate AJ Lopatkin, JM Stokes, EJ Zheng, JH Yang, MK Takahashi, L You, ... Nature microbiology 4 (12), 2109-2117, 2019 | 224 | 2019 |
| Collective antibiotic tolerance: mechanisms, dynamics and intervention HR Meredith, JK Srimani, AJ Lee, AJ Lopatkin, L You Nature chemical biology 11 (3), 182-188, 2015 | 192 | 2015 |
| Predictive biology: modelling, understanding and harnessing microbial complexity AJ Lopatkin, JJ Collins Nature Reviews Microbiology 18 (9), 507-520, 2020 | 142 | 2020 |
| Dissecting the effects of antibiotics on horizontal gene transfer: Analysis suggests a critical role of selection dynamics AJ Lopatkin, TA Sysoeva, L You Bioessays 38 (12), 1283-1292, 2016 | 90 | 2016 |
| Environmental and genetic determinants of plasmid mobility in pathogenic Escherichia coli JH Bethke, A Davidovich, L Cheng, AJ Lopatkin, W Song, JT Thaden, ... Science advances 6 (4), eaax3173, 2020 | 74 | 2020 |
| Conjugation dynamics depend on both the plasmid acquisition cost and the fitness cost H Prensky, A Gomez‐Simmonds, AC Uhlemann, AJ Lopatkin Molecular systems biology 17 (3), e9913, 2021 | 69 | 2021 |
| Applying ecological resistance and resilience to dissect bacterial antibiotic responses HR Meredith, V Andreani, HR Ma, AJ Lopatkin, AJ Lee, DJ Anderson, ... Science advances 4 (12), eaau1873, 2018 | 58 | 2018 |
| Elements of biological oscillations in time and space Y Cao, A Lopatkin, L You Nature Structural & Molecular Biology 23 (12), 1030-1034, 2016 | 54 | 2016 |
| Bacterial temporal dynamics enable optimal design of antibiotic treatment HR Meredith, AJ Lopatkin, DJ Anderson, L You PLoS computational biology 11 (4), e1004201, 2015 | 43 | 2015 |
| Drug detoxification dynamics explain the postantibiotic effect JK Srimani, S Huang, AJ Lopatkin, L You Molecular Systems Biology 13 (10), 948, 2017 | 42 | 2017 |
| A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria JM Stokes, A Gutierrez, AJ Lopatkin, IW Andrews, S French, I Matic, ... Nature Methods 16 (4), 303-306, 2019 | 39 | 2019 |
| Dynamic control and quantification of bacterial population dynamics in droplets S Huang, JK Srimani, AJ Lee, Y Zhang, AJ Lopatkin, KW Leong, L You Biomaterials 61, 239-245, 2015 | 34 | 2015 |
| Metabolic genes on conjugative plasmids are highly prevalent in Escherichia coli and can protect against antibiotic treatment A Palomino, D Gewurz, L DeVine, U Zajmi, J Moralez, F Abu-Rumman, ... The ISME Journal 17 (1), 151-162, 2023 | 32 | 2023 |
| Digital insights into nucleotide metabolism and antibiotic treatment failure AJ Lopatkin, JH Yang Frontiers in digital health 3, 583468, 2021 | 31 | 2021 |
| Quantitative analysis of horizontal gene transfer in complex systems J Moralez, K Szenkiel, K Hamilton, A Pruden, AJ Lopatkin Current Opinion in Microbiology 62, 103-109, 2021 | 28 | 2021 |