Antibiotic substrate selectivity of Pseudomonas aeruginosa MexY and MexB efflux systems is determined by a Goldilocks affinity D Dey, LG Kavanaugh, GL Conn Antimicrobial Agents and Chemotherapy 64 (8), 10.1128/aac. 00496-20, 2020 | 25 | 2020 |
Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical … GA Beggs, JC Ayala, LG Kavanaugh, TD Read, GM Hooks, ... Nucleic Acids Research 49 (7), 4155-4170, 2021 | 21 | 2021 |
Burkholderia multivorans Exhibits Antibiotic Collateral Sensitivity JN Flanagan, L Kavanaugh, TR Steck Microbial Drug Resistance 26 (1), 1-8, 2020 | 9 | 2020 |
Antibiotic cycling reverts extensive drug resistance in Burkholderia multivorans LG Kavanaugh, SK Harrison, JN Flanagan, TR Steck Antimicrobial Agents and Chemotherapy 65 (8), 10.1128/aac. 00611-21, 2021 | 8 | 2021 |
Reciprocal antibiotic collateral sensitivity in Burkholderia multivorans LG Kavanaugh, JN Flanagan, TR Steck International journal of antimicrobial agents 56 (1), 105994, 2020 | 8 | 2020 |
Di-berberine conjugates as chemical probes of Pseudomonas aeruginosa MexXY-OprM efflux function and inhibition LG Kavanaugh, AR Mahoney, D Dey, WM Wuest, GL Conn npj Antimicrobials and Resistance 1 (1), 12, 2023 | 4 | 2023 |
Structural and functional diversity of Resistance-Nodulation-Division (RND) efflux pump transporters with implications for antimicrobial resistance LG Kavanaugh, D Dey, WM Shafer, GL Conn Microbiology and Molecular Biology Reviews 88 (3), e00089-23, 2024 | 1 | 2024 |
Determination of Pseudomonas aeruginosa MexXY-OprM substrate profile in a major efflux knockout system reveals distinct antibiotic substrate classes LG Kavanaugh, SM Hariharan, GL Conn Microbiology Spectrum, e02903-24, 2025 | | 2025 |
517 Validation of the ‘Goldilocks binding affinity’hypothesis for aminoglycoside recognition in the Pseudomonas aeruginosa efflux transporter MexY L Kavanaugh, D Dey, G Conn Journal of Cystic Fibrosis 21, S290, 2022 | | 2022 |
422: Antibiotic collateral sensitivity networks can inform treatment strategies for Burkholderia multivorans infections L Kavanaugh, J Flanagan, S Harrison, T Steck Journal of Cystic Fibrosis 20, S198, 2021 | | 2021 |
BASIS OF SUBSTRATE PREFERENCE IN THE PSEUDOMONAS EFFLUX SYSTEMS MEXY AND MEXB D Dey, LG Kavanaugh, GL Conn PEDIATRIC PULMONOLOGY 55, S166-S167, 2020 | | 2020 |
Review of:" A new substrate triggers susceptibility by uncoupling a bacterial multidrug resistance efflux pump G Conn, LG Kavanaugh | | |