Omicron: what makes the latest SARS-CoV-2 variant of concern so concerning? C Jung, D Kmiec, L Koepke, F Zech, T Jacob, KMJ Sparrer, F Kirchhoff Journal of Virology 96 (6), e02077-21, 2022 | 210 | 2022 |
Monkeypox: A New Threat? D Kmiec, F Kirchhoff International Journal of Molecular Sciences 23 (14), 7866, 2022 | 203 | 2022 |
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro C Prelli Bozzo, R Nchioua, M Volcic, L Koepke, J Krüger, D Schütz, ... Nature Communications 12 (1), 1-13, 2021 | 176* | 2021 |
SARS-CoV-2 is restricted by zinc finger antiviral protein despite preadaptation to the low-CpG environment in humans R Nchioua, D Kmiec, JA Müller, C Conzelmann, R Groß, CM Swanson, ... MBio 11 (5), 10.1128/mbio. 01930-20, 2020 | 135* | 2020 |
The potency of Nef-mediated SERINC5 antagonism correlates with the prevalence of primate lentiviruses in the wild A Heigele, D Kmiec, K Regensburger, S Langer, L Peiffer, CM Stürzel, ... Cell host & microbe 20 (3), 381-391, 2016 | 105 | 2016 |
Vpu-mediated counteraction of tetherin is a major determinant of HIV-1 interferon resistance D Kmiec, SS Iyer, CM Stürzel, D Sauter, BH Hahn, F Kirchhoff MBio 7 (4), e00934-16, 2016 | 58 | 2016 |
CpG Frequency in the 5′ Third of the env Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein D Kmiec, R Nchioua, S Sherrill-Mix, CM Stürzel, E Heusinger, E Braun, ... MBio 11 (1), 10.1128/mbio. 02903-19, 2020 | 54 | 2020 |
S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies D Kmiec, MJ Lista, M Ficarelli, CM Swanson, SJD Neil Plos pathogens 17 (10), e1009726, 2021 | 38 | 2021 |
SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells R Nchioua, A Schundner, D Kmiec, C Prelli Bozzo, F Zech, L Koepke, ... Journal of Virology, e00594-22, 2022 | 34 | 2022 |
Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhibit enhanced phagocytosis and immunogenicity S Jones, C Asokanathan, D Kmiec, J Irvine, R Fleck, D Xing, B Moore, ... Vaccine 32 (33), 4234-4242, 2014 | 32 | 2014 |
PLGA nano/micro particles encapsulated with pertussis toxoid (PTd) enhances Th1/Th17 immune response in a murine model P Li, C Asokanathan, F Liu, KK Khaing, D Kmiec, X Wei, B Song, D Xing, ... International journal of pharmaceutics 513 (1-2), 183-190, 2016 | 31 | 2016 |
Cellular Factors Targeting HIV-1 Transcriptionand Viral RNA Transcripts R Nchioua, M Bosso, D Kmiec, F Kirchhoff Viruses 12 (5), 495, 2020 | 28 | 2020 |
Structural basis for tetherin antagonism as a barrier to zoonotic lentiviral transmission CZ Buffalo, CM Stürzel, E Heusinger, D Kmiec, F Kirchhoff, JH Hurley, ... Cell host & microbe 26 (3), 359-368. e8, 2019 | 28 | 2019 |
SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue D Kmiec, B Akbil, S Ananth, D Hotter, K Sparrer, CM Stürzel, B Trautz, ... PLoS pathogens 14 (8), e1007269, 2018 | 23 | 2018 |
Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA. 1 R Nchioua, A Schundner, S Klute, L Koepke, M Hirschenberger, ... Life Science Alliance 6 (6), 2023 | 18 | 2023 |
Preadaptation of simian immunodeficiency virus SIVsmm facilitated env-mediated counteraction of human tetherin by human immunodeficiency virus Type 2 E Heusinger, K Deppe, P Sette, C Krapp, D Kmiec, SF Kluge, PA Marx, ... Journal of virology 92 (18), e00276-18, 2018 | 18 | 2018 |
An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins M Bosso, CM Stürzel, D Kmiec, SS Badarinarayan, E Braun, J Ito, K Sato, ... Cell reports 36 (12), 2021 | 14 | 2021 |
Endogenous IFITMs boost SARS-Coronavirus 1 and 2 replication while overexpression inhibits infection by relocalizing ACE2 Q Xie, CP Bozzo, L Eiben, S Nöttger, D Kmiec, R Nchioua, D Niemeyer, ... iScience, 106395, 2023 | 10 | 2023 |
When good turns bad: how viruses exploit innate immunity factors CP Bozzo, D Kmiec, F Kirchhoff Current opinion in virology 52, 60-67, 2022 | 10 | 2022 |
The Delta variant of SARS-CoV-2 maintains high sensitivity to interferons in human lung cells R Nchioua, A Schundner, S Klute, S Noettger, F Zech, L Koepke, A Graf, ... | 9* | 2021 |