PARP inhibition: PARP1 and beyond M Rouleau, A Patel, MJ Hendzel, SH Kaufmann, GG Poirier Nature Reviews Cancer 10 (4), 293-301, 2010 | 1618 | 2010 |
Nonhomologous end joining drives poly (ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells AG Patel, JN Sarkaria, SH Kaufmann Proceedings of the National Academy of Sciences 108 (8), 3406-3411, 2011 | 621 | 2011 |
A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ... Nature Medicine 26 (5), 792-802, 2020 | 567 | 2020 |
Temperature triggered self-assembly of polypeptides into multivalent spherical micelles MR Dreher, AJ Simnick, K Fischer, RJ Smith, A Patel, M Schmidt, ... Journal of the American Chemical Society 130 (2), 687-694, 2008 | 468 | 2008 |
Failure of iniparib to inhibit poly (ADP-Ribose) polymerase in vitro AG Patel, SB De Lorenzo, KS Flatten, GG Poirier, SH Kaufmann Clinical Cancer Research 18 (6), 1655-1662, 2012 | 256 | 2012 |
The elephant and the blind men: making sense of PARP inhibitors in homologous recombination deficient tumor cells SB De Lorenzo, AG Patel, RM Hurley, SH Kaufmann Front Oncol 3 (228.10), 3389, 2013 | 159 | 2013 |
How does doxorubicin work? AG Patel, SH Kaufmann eLife Sciences 1, 2012 | 127 | 2012 |
Enhanced killing of cancer cells by Poly (ADP-ribose) Polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes AG Patel, KS Flatten, PA Schneider, NT Dai, JS McDonald, GG Poirier, ... Journal of Biological Chemistry 287 (6), 4198-4210, 2012 | 111 | 2012 |
EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma AD Durbin, T Wang, VK Wimalasena, MW Zimmerman, D Li, NV Dharia, ... Cancer Discovery 12 (3), 730-751, 2022 | 105 | 2022 |
Neuroblastoma: When differentiation goes awry M Zeineldin, AG Patel, MA Dyer Neuron 110 (18), 2916-2928, 2022 | 81 | 2022 |
Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure TV Damodaran, AG Patel, ST Greenfield, HK Dressman, SM Lin, ... Biochemical pharmacology 71 (4), 497-520, 2006 | 67 | 2006 |
Poly (ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells AM Huehls, JM Wagner, CJ Huntoon, L Geng, C Erlichman, AG Patel, ... Cancer research 71 (14), 4944-4954, 2011 | 64 | 2011 |
Immunodetection of human topoisomerase I-DNA covalent complexes AG Patel, KS Flatten, KL Peterson, TG Beito, PA Schneider, AL Perkins, ... Nucleic acids research 44 (6), 2816-2826, 2016 | 59 | 2016 |
Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes S Sengupta, S Das, AC Crespo, AM Cornel, AG Patel, NR Mahadevan, ... Nature cancer 3 (10), 1228-1246, 2022 | 52 | 2022 |
The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma AG Patel, X Chen, X Huang, MR Clay, NL Komarova, MJ Krasin, A Pappo, ... Developmental cell 57 (10), 1226-1240. e8, 2022 | 51 | 2022 |
Sarin (nerve agent GB)-induced differential expression of mRNA coding for the acetylcholinesterase gene in the rat central nervous system TV Damodaran, KH Jones, AG Patel, MB Abou-Donia Biochemical pharmacology 65 (12), 2041-2047, 2003 | 50 | 2003 |
Toxicogenomic studies of the rat brain at an early time point following acute sarin exposure TV Damodaran, ST Greenfield, AG Patel, HK Dressman, SK Lin, ... Neurochemical research 31 (3), 367-381, 2006 | 39 | 2006 |
Poly (ADP-Ribose) Polymerase Inhibitor Hypersensitivity in Aggressive Myeloproliferative Neoplasms KW Pratz, BD Koh, AG Patel, KS Flatten, W Poh, JG Herman, R Dilley, ... Clinical Cancer Research 22 (15), 3894-3902, 2016 | 29 | 2016 |
Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma R Nguyen, AG Patel, LM Griffiths, J Dapper, EA Stewart, J Houston, ... Cancer Immunology, Immunotherapy 70, 721-732, 2021 | 26 | 2021 |
Identification of a modular super-enhancer in murine retinal development V Honnell, JL Norrie, AG Patel, C Ramirez, J Zhang, YH Lai, S Wan, ... Nature Communications 13 (1), 253, 2022 | 22 | 2022 |