| The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4 C Kang, Q Xu, TD Martin, MZ Li, M Demaria, L Aron, T Lu, BA Yankner, ... Science 349 (6255), aaa5612, 2015 | 951 | 2015 |
| Profound tissue specificity in proliferation control underlies cancer drivers and aneuploidy patterns LM Sack, T Davoli, MZ Li, Y Li, Q Xu, K Naxerova, EC Wooten, ... Cell 173 (2), 499-514. e23, 2018 | 222 | 2018 |
| KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer JJ Yeh, ED Routh, T Rubinas, J Peacock, TD Martin, XJ Shen, RS Sandler, ... Molecular cancer therapeutics 8 (4), 834-843, 2009 | 183 | 2009 |
| Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion TD Martin, XW Chen, REW Kaplan, AR Saltiel, CL Walker, DJ Reiner, ... Molecular cell 53 (2), 209-220, 2014 | 166 | 2014 |
| The RalGEF-Ral effector signaling network: the road less traveled for anti-Ras drug discovery NF Neel, TD Martin, JK Stratford, TP Zand, DJ Reiner, CJ Der Genes & cancer 2 (3), 275-287, 2011 | 146 | 2011 |
| Ral small GTPase signaling and oncogenesis: more than just 15 minutes of fame LR Gentry, TD Martin, DJ Reiner, CJ Der Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1843 (12), 2976-2988, 2014 | 130 | 2014 |
| The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation TD Martin, RS Patel, DR Cook, MY Choi, A Patil, AC Liang, MZ Li, ... Science 373 (6561), 1327-1335, 2021 | 125 | 2021 |
| Activation and involvement of Ral GTPases in colorectal cancer TD Martin, JC Samuel, ED Routh, CJ Der, JJ Yeh Cancer research 71 (1), 206-215, 2011 | 99 | 2011 |
| A role for mitochondrial translation in promotion of viability in K-Ras mutant cells TD Martin, DR Cook, MY Choi, MZ Li, KM Haigis, SJ Elledge Cell reports 20 (2), 427-438, 2017 | 91 | 2017 |
| Coordinate regulation of lipogenesis, the assembly and secretion of apolipoprotein B-containing lipoproteins by sterol response element binding protein 1 SL Wang, EZ Du, TD Martin, RA Davis Journal of Biological Chemistry 272 (31), 19351-19358, 1997 | 85 | 1997 |
| The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector NF Neel, KL Rossman, TD Martin, TK Hayes, JJ Yeh, CJ Der Molecular and cellular biology, 2012 | 76 | 2012 |
| Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent … D Vigil, TD Martin, F Williams, JJ Yeh, SL Campbell, CJ Der Journal of Biological Chemistry 285 (45), 34729-34740, 2010 | 72 | 2010 |
| Multicolor monitoring of dysregulated protein kinases in chronic myelogenous leukemia Q Wang, EI Zimmerman, A Toutchkine, TD Martin, LM Graves, ... ACS Chemical biology 5 (9), 887-895, 2010 | 63 | 2010 |
| Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases LR Gentry, A Nishimura, AD Cox, TD Martin, D Tsygankov, M Nishida, ... Journal of Biological Chemistry 290 (37), 22851-22861, 2015 | 50 | 2015 |
| Phosphorylation by protein kinase Cα regulates RalB small GTPase protein activation, subcellular localization, and effector utilization TD Martin, N Mitin, AD Cox, JJ Yeh, CJ Der Journal of Biological Chemistry 287 (18), 14827-14836, 2012 | 45 | 2012 |
| Differential involvement of RalA and RalB in colorectal cancer TD Martin, CJ Der Small GTPases 3 (2), 126-130, 2012 | 43 | 2012 |
| Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth DR Cook, M Kang, TD Martin, JA Galanko, GH Loeza, DG Trembath, ... Cancer research 82 (1), 90-104, 2022 | 34 | 2022 |
| Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation AR Kidd III, JL Snider, TD Martin, SF Graboski, CJ Der, AD Cox International Journal of Radiation Oncology* Biology* Physics 78 (1), 205-212, 2010 | 31 | 2010 |
| Genetic analysis of cancer drivers reveals cohesin and CTCF as suppressors of PD-L1 E Oreskovic, EC Wheeler, KE Mengwasser, E Fujimura, TD Martin, ... Proceedings of the National Academy of Sciences 119 (7), e2120540119, 2022 | 25 | 2022 |
| Response to MLN8237 in pancreatic cancer is not dependent on RalA phosphorylation NF Neel, JK Stratford, V Shinde, JA Ecsedy, TD Martin, CJ Der, JJ Yeh Molecular cancer therapeutics 13 (1), 122-133, 2014 | 21 | 2014 |
