| Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ... Nature 478 (7370), 529-533, 2011 | 1757 | 2011 |
| A physical and functional map of the human TNF-α/NF-κB signal transduction pathway T Bouwmeester, A Bauch, H Ruffner, PO Angrand, G Bergamini, ... Nature cell biology 6 (2), 97-105, 2004 | 1348 | 2004 |
| Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors M Bantscheff, D Eberhard, Y Abraham, S Bastuck, M Boesche, S Hobson, ... Nature biotechnology 25 (9), 1035-1044, 2007 | 1234 | 2007 |
| Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes M Bantscheff, C Hopf, MM Savitski, A Dittmann, P Grandi, AM Michon, ... Nature biotechnology 29 (3), 255-265, 2011 | 797 | 2011 |
| IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression A Sadik, LFS Patterson, S Öztürk, SR Mohapatra, V Panitz, PF Secker, ... Cell 182 (5), 1252-1270. e34, 2020 | 405 | 2020 |
| Advanced MALDI mass spectrometry imaging in pharmaceutical research and drug development S Schulz, M Becker, MR Groseclose, S Schadt, C Hopf Current opinion in biotechnology 55, 51-59, 2019 | 323 | 2019 |
| Narp and NP1 form heterocomplexes that function in developmental and activity-dependent synaptic plasticity D Xu, C Hopf, R Reddy, RW Cho, L Guo, A Lanahan, RS Petralia, ... Neuron 39 (3), 513-528, 2003 | 314 | 2003 |
| Alzheimer’s-causing mutations shift Aβ length by destabilizing γ-secretase-Aβn interactions M Szaruga, B Munteanu, S Lismont, S Veugelen, K Horré, M Mercken, ... Cell 170 (3), 443-456. e14, 2017 | 268 | 2017 |
| Synaptically targeted narp plays an essential role in the aggregation of AMPA receptors at excitatory synapses in cultured spinal neurons R O'Brien, D Xu, R Mi, X Tang, C Hopf, P Worley Journal of Neuroscience 22 (11), 4487-4498, 2002 | 196 | 2002 |
| Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson’s disease-related toxicity in human neurons N Ramsden, J Perrin, Z Ren, BD Lee, N Zinn, VL Dawson, D Tam, M Bova, ... ACS chemical biology 6 (10), 1021-1028, 2011 | 180 | 2011 |
| Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas M Friedrich, R Sankowski, L Bunse, M Kilian, E Green, ... Nature cancer 2 (7), 723-740, 2021 | 172 | 2021 |
| A selective inhibitor reveals PI3Kγ dependence of TH17 cell differentiation G Bergamini, K Bell, S Shimamura, T Werner, A Cansfield, K Müller, ... Nature chemical biology 8 (6), 576-582, 2012 | 155 | 2012 |
| Optimized chemical proteomics assay for kinase inhibitor profiling G Médard, F Pachl, B Ruprecht, S Klaeger, S Heinzlmeir, D Helm, H Qiao, ... Journal of proteome research 14 (3), 1574-1586, 2015 | 153 | 2015 |
| Structural basis and SAR for G007-LK, a lead stage 1, 2, 4-triazole based specific tankyrase 1/2 inhibitor A Voronkov, DD Holsworth, J Waaler, SR Wilson, B Ekblad, ... Journal of medicinal chemistry 56 (7), 3012-3023, 2013 | 153 | 2013 |
| mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE RW Cho, JM Park, SBE Wolff, D Xu, C Hopf, J Kim, RC Reddy, RS Petralia, ... Neuron 57 (6), 858-871, 2008 | 152 | 2008 |
| The commonly used PI3-kinase probe LY294002 is an inhibitor of BET bromodomains A Dittmann, T Werner, CW Chung, MM Savitski, M Fälth Savitski, ... ACS chemical biology 9 (2), 495-502, 2014 | 131 | 2014 |
| Agrin Binding to α-Dystroglycan: DOMAINS OF AGRIN NECESSARY TO INDUCE ACETYLCHOLINE RECEPTOR CLUSTERING ARE OVERLAPPING BUT NOT IDENTICAL TO THE α-DYSTROGLYCAN-BINDING REGION (∗) C Hopf, W Hoch Journal of Biological Chemistry 271 (9), 5231-5236, 1996 | 119 | 1996 |
| Identification of serum proteins bound to industrial nanomaterials H Ruh, B Kühl, G Brenner-Weiss, C Hopf, S Diabaté, C Weiss Toxicology letters 208 (1), 41-50, 2012 | 109 | 2012 |
| Dimerization of the muscle-specific kinase induces tyrosine phosphorylation of acetylcholine receptors and their aggregation on the surface of myotubes C Hopf, W Hoch Journal of Biological Chemistry 273 (11), 6467-6473, 1998 | 109 | 1998 |
| Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI Q Zhou, A Fülöp, C Hopf Analytical and bioanalytical chemistry 413, 2599-2617, 2021 | 95 | 2021 |
Gerard DrewesCellzome/GlaxoSmithKline R&D確認したメール アドレス: gsk.com
