Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation JB Shaw, W Li, DD Holden, Y Zhang, J Griep-Raming, RT Fellers, ... Journal of the American Chemical Society 135 (34), 12646-12651, 2013 | 413 | 2013 |
ProSight Lite: graphical software to analyze top‐down mass spectrometry data RT Fellers, JB Greer, BP Early, X Yu, RD LeDuc, NL Kelleher, PM Thomas Proteomics 15 (7), 1235-1238, 2015 | 278 | 2015 |
Identification and quantification of proteoforms by mass spectrometry LV Schaffer, RJ Millikin, RM Miller, LC Anderson, RT Fellers, Y Ge, ... Proteomics 19 (10), 1800361, 2019 | 224 | 2019 |
Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence AD Catherman, KR Durbin, DR Ahlf, BP Early, RT Fellers, JC Tran, ... Molecular & Cellular Proteomics 12 (12), 3465-3473, 2013 | 189 | 2013 |
Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes JO Kafader, RD Melani, KR Durbin, B Ikwuagwu, BP Early, RT Fellers, ... Nature methods 17 (4), 391-394, 2020 | 167 | 2020 |
Diversity of amyloid-beta proteoforms in the Alzheimer’s disease brain NC Wildburger, TJ Esparza, RD LeDuc, RT Fellers, PM Thomas, ... Scientific reports 7 (1), 9520, 2017 | 167 | 2017 |
Accurate sequence analysis of a monoclonal antibody by top-down and middle-down orbitrap mass spectrometry applying multiple ion activation techniques L Fornelli, K Srzentić, R Huguet, C Mullen, S Sharma, V Zabrouskov, ... Analytical chemistry 90 (14), 8421-8429, 2018 | 163 | 2018 |
Quantitation and identification of thousands of human proteoforms below 30 kDa KR Durbin, L Fornelli, RT Fellers, PF Doubleday, M Narita, NL Kelleher Journal of proteome research 15 (3), 976-982, 2016 | 125 | 2016 |
The first pilot project of the consortium for top‐down proteomics: a status report X Dang, J Scotcher, S Wu, RK Chu, N Tolić, I Ntai, PM Thomas, RT Fellers, ... Proteomics 14 (10), 1130-1140, 2014 | 121 | 2014 |
Applying label-free quantitation to top down proteomics I Ntai, K Kim, RT Fellers, OS Skinner, AD Smith IV, BP Early, JP Savaryn, ... Analytical chemistry 86 (10), 4961-4968, 2014 | 115 | 2014 |
High-throughput analysis of intact human proteins using UVPD and HCD on an orbitrap mass spectrometer TP Cleland, CJ DeHart, RT Fellers, AJ VanNispen, JB Greer, RD LeDuc, ... Journal of proteome research 16 (5), 2072-2079, 2017 | 109 | 2017 |
Ultraviolet photodissociation for characterization of whole proteins on a chromatographic time scale JR Cannon, MB Cammarata, SA Robotham, VC Cotham, JB Shaw, ... Analytical chemistry 86 (4), 2185-2192, 2014 | 108 | 2014 |
Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk I Ntai, L Fornelli, CJ DeHart, JE Hutton, PF Doubleday, RD LeDuc, ... Proceedings of the National Academy of Sciences 115 (16), 4140-4145, 2018 | 107 | 2018 |
Identification and characterization of human proteoforms by top-down LC-21 tesla FT-ICR mass spectrometry LC Anderson, CJ DeHart, NK Kaiser, RT Fellers, DF Smith, JB Greer, ... Journal of proteome research 16 (2), 1087-1096, 2017 | 102 | 2017 |
The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells RD Melani, VR Gerbasi, LC Anderson, JW Sikora, TK Toby, JE Hutton, ... Science 375 (6579), 411-418, 2022 | 100 | 2022 |
Integrated bottom-up and top-down proteomics of patient-derived breast tumor xenografts I Ntai, RD LeDuc, RT Fellers, P Erdmann-Gilmore, SR Davies, J Rumsey, ... Molecular & Cellular Proteomics 15 (1), 45-56, 2016 | 99 | 2016 |
Advancing top-down analysis of the human proteome using a benchtop quadrupole-orbitrap mass spectrometer L Fornelli, KR Durbin, RT Fellers, BP Early, JB Greer, RD LeDuc, ... Journal of proteome research 16 (2), 609-618, 2017 | 96 | 2017 |
The C-score: a Bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomics RD LeDuc, RT Fellers, BP Early, JB Greer, PM Thomas, NL Kelleher Journal of proteome research 13 (7), 3231-3240, 2014 | 95 | 2014 |
Proton transfer charge reduction enables high-throughput top-down analysis of large proteoforms R Huguet, C Mullen, K Srzentić, JB Greer, RT Fellers, V Zabrouskov, ... Analytical chemistry 91 (24), 15732-15739, 2019 | 84 | 2019 |
A five-level classification system for proteoform identifications LM Smith, PM Thomas, MR Shortreed, LV Schaffer, RT Fellers, RD LeDuc, ... Nature methods 16 (10), 939-940, 2019 | 79 | 2019 |