TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity A Caputo, E Caci, L Ferrera, N Pedemonte, C Barsanti, E Sondo, U Pfeffer, ... Science 322 (5901), 590-594, 2008 | 1464 | 2008 |
Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening N Pedemonte, GL Lukacs, K Du, E Caci, O Zegarra-Moran, LJV Galietta, ... The Journal of clinical investigation 115 (9), 2564-2571, 2005 | 685 | 2005 |
Structure and function of TMEM16 proteins (anoctamins) N Pedemonte, LJV Galietta Physiological reviews 94 (2), 419-459, 2014 | 578 | 2014 |
Nanomolar affinity small molecule correctors of defective ΔF508-CFTR chloride channel gating H Yang, AA Shelat, RK Guy, VS Gopinath, T Ma, K Du, GL Lukacs, ... Journal of Biological Chemistry 278 (37), 35079-35085, 2003 | 268 | 2003 |
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening T Ma, L Vetrivel, H Yang, N Pedemonte, O Zegarra-Moran, LJV Galietta, ... Journal of Biological Chemistry 277 (40), 37235-37241, 2002 | 255 | 2002 |
Phenylglycine and sulfonamide correctors of defective ΔF508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating N Pedemonte, ND Sonawane, A Taddei, J Hu, O Zegarra-Moran, YF Suen, ... Molecular pharmacology 67 (5), 1797-1807, 2005 | 195 | 2005 |
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells X Fang, Y Song, J Hirsch, LJV Galietta, N Pedemonte, RL Zemans, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 290 (2 …, 2006 | 190 | 2006 |
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia P Scudieri, E Caci, S Bruno, L Ferrera, M Schiavon, E Sondo, V Tomati, ... The Journal of physiology 590 (23), 6141-6155, 2012 | 183 | 2012 |
Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels N Pedemonte, E Caci, E Sondo, A Caputo, K Rhoden, U Pfeffer, ... The Journal of Immunology 178 (8), 5144-5153, 2007 | 173 | 2007 |
Influence of cell background on pharmacological rescue of mutant CFTR N Pedemonte, V Tomati, E Sondo, LJV Galietta American Journal of Physiology-Cell Physiology 298 (4), C866-C874, 2010 | 149 | 2010 |
Evidence against the rescue of defective ΔF508-CFTR cellular processing by curcumin in cell culture and mouse models Y Song, ND Sonawane, D Salinas, L Qian, N Pedemonte, LJV Galietta, ... Journal of Biological Chemistry 279 (39), 40629-40633, 2004 | 145 | 2004 |
Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules M Stravalaci, I Pagani, EM Paraboschi, M Pedotti, A Doni, F Scavello, ... Nature immunology 23 (2), 275-286, 2022 | 131 | 2022 |
Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening O Kalid, M Mense, S Fischman, A Shitrit, H Bihler, E Ben-Zeev, N Schutz, ... Journal of computer-aided molecular design 24, 971-991, 2010 | 111 | 2010 |
Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling E Sondo, V Tomati, E Caci, AI Esposito, U Pfeffer, N Pedemonte, ... American Journal of Physiology-Cell Physiology 301 (4), C872-C885, 2011 | 103 | 2011 |
Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis AKMA Haque, A Dewerth, JS Antony, J Riethmüller, GR Schweizer, ... Scientific reports 8 (1), 16776, 2018 | 78 | 2018 |
Antihypertensive 1, 4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations N Pedemonte, T Diena, E Caci, E Nieddu, M Mazzei, R Ravazzolo, ... Molecular pharmacology 68 (6), 1736-1746, 2005 | 74 | 2005 |
Proteomic analysis of the airway surface liquid: modulation by proinflammatory cytokines G Candiano, M Bruschi, N Pedemonte, L Musante, R Ravazzolo, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (1 …, 2007 | 73 | 2007 |
Pharmacological inhibition of the ubiquitin ligase RNF5 rescues F508del-CFTR in cystic fibrosis airway epithelia E Sondo, F Falchi, E Caci, L Ferrera, E Giacomini, E Pesce, V Tomati, ... Cell Chemical Biology 25 (7), 891-905. e8, 2018 | 72 | 2018 |
Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis … N Pedemonte, V Tomati, E Sondo, E Caci, E Millo, A Armirotti, G Damonte, ... Journal of Biological Chemistry 286 (17), 15215-15226, 2011 | 68 | 2011 |
Gelsolin secretion in interleukin-4–treated bronchial epithelia and in asthmatic airways G Candiano, M Bruschi, N Pedemonte, E Caci, S Liberatori, L Bini, ... American journal of respiratory and critical care medicine 172 (9), 1090-1096, 2005 | 67 | 2005 |