Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan KT Howitz, KJ Bitterman, HY Cohen, DW Lamming, S Lavu, JG Wood, ... Nature 425 (6954), 191-196, 2003 | 4938 | 2003 |
Sirtuin activators mimic caloric restriction and delay ageing in metazoans JG Wood, B Rogina, S Lavu, K Howitz, SL Helfand, M Tatar, D Sinclair Nature 430 (7000), 686-689, 2004 | 2350 | 2004 |
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae RM Anderson, KJ Bitterman, JG Wood, O Medvedik, DA Sinclair Nature 423 (6936), 181-185, 2003 | 954 | 2003 |
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels RM Anderson, KJ Bitterman, JG Wood, O Medvedik, H Cohen, SS Lin, ... Journal of Biological Chemistry 277 (21), 18881-18890, 2002 | 379 | 2002 |
MicroReview: small molecules that regulate lifespan: evidence for xenohormesis DW Lamming, JG Wood, DA Sinclair Molecular microbiology 53 (4), 1003-1009, 2004 | 289 | 2004 |
Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6 S Gaubatz, JG Wood, DM Livingston Proceedings of the National Academy of Sciences 95 (16), 9190-9195, 1998 | 240 | 1998 |
Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila JG Wood, BC Jones, N Jiang, C Chang, S Hosier, P Wickremesinghe, ... Proceedings of the National Academy of Sciences 113 (40), 11277-11282, 2016 | 223 | 2016 |
Chromatin remodeling in the aging genome of Drosophila JG Wood, S Hillenmeyer, C Lawrence, C Chang, S Hosier, W Lightfoot, ... Aging cell 9 (6), 971-978, 2010 | 198 | 2010 |
dSir2 and Dmp53 interact to mediate aspects of CR-dependent life span extension in D. melanogaster JH Bauer, SNS Morris, C Chang, T Flatt, JG Wood, SL Helfand Aging (Albany NY) 1 (1), 38, 2008 | 185* | 2008 |
Chromatin structure and transposable elements in organismal aging JG Wood, SL Helfand Frontiers in genetics 4, 274, 2013 | 147 | 2013 |
Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span M Pu, Z Ni, M Wang, X Wang, JG Wood, SL Helfand, H Yu, SS Lee Genes & development 29 (7), 718-731, 2015 | 137 | 2015 |
A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan BC Jones, JG Wood, C Chang, AD Tam, MJ Franklin, ER Siegel, ... Nature communications 7 (1), 13856, 2016 | 124 | 2016 |
Increased expression of Drosophila Sir 2 extends life span in a dose-dependent manner R Whitaker, S Faulkner, R Miyokawa, L Burhenn, M Henriksen, JG Wood, ... Aging (Albany NY) 5 (9), 682, 2013 | 115 | 2013 |
Sirt4 is a mitochondrial regulator of metabolism and lifespan in Drosophila melanogaster JG Wood, B Schwer, PC Wickremesinghe, DA Hartnett, L Burhenn, ... Proceedings of the National Academy of Sciences 115 (7), 1564-1569, 2018 | 86 | 2018 |
Avirulence genes from Pseudomonas syringae pathovars phaseolicola and pisi confer specificity towards both host and non-host species AJ Fillingham, J Wood, JR Bevan, IR Crute, JW Mansfield, JD Taylor, ... Physiological and Molecular Plant Pathology 40 (1), 1-15, 1992 | 83 | 1992 |
Dietary and genetic effects on age-related loss of gene silencing reveal epigenetic plasticity of chromatin repression during aging N Jiang, G Du, E Tobias, JG Wood, R Whitaker, N Neretti, SL Helfand Aging (Albany NY) 5 (11), 813, 2013 | 65 | 2013 |
Sirt6 regulates lifespan in Drosophila melanogaster JR Taylor, JG Wood, E Mizerak, S Hinthorn, J Liu, M Finn, S Gordon, ... Proceedings of the National Academy of Sciences 119 (5), e2111176119, 2022 | 43 | 2022 |
TPE or not TPE? It's no longer a question JG Wood, DA Sinclair Trends in pharmacological sciences 23 (1), 1-4, 2002 | 30 | 2002 |
Correction: Corrigendum: Sirtuin activators mimic caloric restriction and delay ageing in metazoans JG Wood, B Rogina, S Lavu, K Howitz, SL Helfand, M Tatar, D Sinclair Nature 431 (7004), 107-107, 2004 | 26 | 2004 |
Two different E2F6 proteins generated by alternative splicing and internal translation initiation T Dahme, J Wood, DM Livingston, S Gaubatz European journal of biochemistry 269 (20), 5030-5036, 2002 | 25 | 2002 |