Oxidative stress: The core pathogenesis and mechanism of Alzheimer’s disease R Bai, J Guo, XY Ye, Y Xie, T Xie Ageing research reviews 77, 101619, 2022 | 408 | 2022 |
Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation R Bai, C Yao, Z Zhong, J Ge, Z Bai, X Ye, T Xie, Y Xie European Journal of Medicinal Chemistry 213, 113165, 2021 | 131 | 2021 |
Natural terpenoids with anti-inflammatory activities: Potential leads for anti-inflammatory drug discovery J Ge, Z Liu, Z Zhong, L Wang, X Zhuo, J Li, X Jiang, XY Ye, T Xie, R Bai Bioorganic Chemistry 124, 105817, 2022 | 95 | 2022 |
Design, synthesis, and biological evaluation of 1, 2, 4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates J Liu, Q Liu, X Yang, S Xu, H Zhang, R Bai, H Yao, J Jiang, M Shen, X Wu, ... Bioorganic & medicinal chemistry 21 (24), 7742-7751, 2013 | 82 | 2013 |
Chemical approaches for the enhancement of porphyrin skeleton-based photodynamic therapy Y Lin, T Zhou, R Bai, Y Xie Journal of enzyme inhibition and medicinal chemistry 35 (1), 1080-1099, 2020 | 81 | 2020 |
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities X Jiang, K Wu, R Bai, P Zhang, Y Zhang European Journal of Medicinal Chemistry 229, 114085, 2022 | 74 | 2022 |
Anti-tumor drug discovery based on natural product β-elemene: Anti-tumor mechanisms and structural modification Z Bai, C Yao, J Zhu, Y Xie, XY Ye, R Bai, T Xie Molecules 26 (6), 1499, 2021 | 70 | 2021 |
Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease C Zhang, K Yang, S Yu, J Su, S Yuan, J Han, Y Chen, J Gu, T Zhou, R Bai, ... European Journal of Medicinal Chemistry 180, 367-382, 2019 | 66 | 2019 |
Medicinal chemistry updates of novel HDACs inhibitors (2020 to present) X He, Z Hui, L Xu, R Bai, Y Gao, Z Wang, T Xie, XY Ye European Journal of Medicinal Chemistry 227, 113946, 2022 | 56 | 2022 |
Discovery of novel tacrine–pyrimidone hybrids as potent dual AChE/GSK-3 inhibitors for the treatment of Alzheimer’s disease H Yao, G Uras, P Zhang, S Xu, Y Yin, J Liu, S Qin, X Li, S Allen, R Bai, ... Journal of Medicinal Chemistry 64 (11), 7483-7506, 2021 | 56 | 2021 |
Combination of chemotherapy and gaseous signaling molecular therapy: Novel β‐elemene nitric oxide donor derivatives against leukemia J Zhu, X Jiang, X Luo, R Zhao, J Li, H Cai, XY Ye, R Bai, T Xie Drug Development Research 84 (4), 718-735, 2023 | 53 | 2023 |
Second generation β-elemene nitric oxide derivatives with reasonable linkers: potential hybrids against malignant brain glioma R Bai, J Zhu, Z Bai, Q Mao, Y Zhang, Z Hui, X Luo, XY Ye, T Xie Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 379-385, 2022 | 51 | 2022 |
Current natural products with antihypertensive activity BAI Ren-Ren, WU Xiao-Ming, XU Jin-Yi Chinese journal of natural medicines 13 (10), 721-729, 2015 | 51 | 2015 |
Hydroxypyridinone-based iron chelators with broad-ranging biological activities X Jiang, T Zhou, R Bai, Y Xie Journal of Medicinal Chemistry 63 (23), 14470-14501, 2020 | 45 | 2020 |
Heck reaction prediction using a transformer model based on a transfer learning strategy L Wang, C Zhang, R Bai, J Li, H Duan Chemical Communications 56 (65), 9368-9371, 2020 | 45 | 2020 |
Races of small molecule clinical trials for the treatment of COVID‐19: an up‐to‐date comprehensive review S Hu, S Jiang, X Qi, R Bai, XY Ye, T Xie Drug Development Research 83 (1), 16-54, 2022 | 41 | 2022 |
Coordinating Activation Strategy‐Induced Selective C− H Trifluoromethylation of Anilines J Xu, K Cheng, C Shen, R Bai, Y Xie, P Zhang ChemCatChem 10 (5), 965-970, 2018 | 38 | 2018 |
Transfer learning: making retrosynthetic predictions based on a small chemical reaction dataset scale to a new level R Bai, C Zhang, L Wang, C Yao, J Ge, H Duan Molecules 25 (10), 2357, 2020 | 37 | 2020 |
Synthesis and biological evaluation of 4′-[(benzimidazole-1-yl) methyl] biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists R Bai, Z Wei, J Liu, W Xie, H Yao, X Wu, J Jiang, Q Wang, J Xu Bioorganic & medicinal chemistry 20 (15), 4661-4667, 2012 | 37 | 2012 |
Discovery of small-molecule candidates against inflammatory bowel disease R Bai, X Jie, C Yao, Y Xie European journal of medicinal chemistry 185, 111805, 2020 | 36 | 2020 |