T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition E Hui, J Cheung, J Zhu, X Su, MJ Taylor, HA Wallweber, DK Sasmal, ... Science 355 (6332), 1428-1433, 2017 | 1689 | 2017 |
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness J Huang, VI Zarnitsyna, B Liu, LJ Edwards, N Jiang, BD Evavold, C Zhu Nature 464 (7290), 932-936, 2010 | 600 | 2010 |
A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4+ T cells J Huang, M Brameshuber, X Zeng, J Xie, Q Li, Y Chien, S Valitutti, ... Immunity 39 (5), 846-857, 2013 | 421 | 2013 |
γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response X Zeng, YL Wei, J Huang, EW Newell, H Yu, BA Kidd, MS Kuhns, ... Immunity 37 (3), 524-534, 2012 | 234 | 2012 |
Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination N Jiang, J Huang, LJ Edwards, B Liu, Y Zhang, CD Beal, BD Evavold, ... Immunity 34 (1), 13-23, 2011 | 200 | 2011 |
High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+ T cell responses JJ Sabatino Jr, J Huang, C Zhu, BD Evavold Journal of Experimental Medicine 208 (1), 81-90, 2011 | 199 | 2011 |
Antigen-presenting cell-intrinsic PD-1 neutralizes PD-L1 in cis to attenuate PD-1 signaling in T cells Y Zhao, DL Harrison, Y Song, J Ji, J Huang, E Hui Cell reports 24 (2), 379-390. e6, 2018 | 184 | 2018 |
A self-illuminating nanoparticle for inflammation imaging and cancer therapy X Xu, H An, D Zhang, H Tao, Y Dou, X Li, J Huang, J Zhang Science advances 5 (1), eaat2953, 2019 | 183 | 2019 |
CD8+ T cells and NK cells: parallel and complementary soldiers of immunotherapy J Rosenberg, J Huang Current opinion in chemical engineering 19, 9-20, 2018 | 164 | 2018 |
A proresolving peptide nanotherapy for site‐specific treatment of inflammatory bowel disease by regulating proinflammatory microenvironment and gut microbiota C Li, Y Zhao, J Cheng, J Guo, Q Zhang, X Zhang, J Ren, F Wang, J Huang, ... Advanced science 6 (18), 1900610, 2019 | 161 | 2019 |
Quantifying the effects of molecular orientation and length on two-dimensional receptor-ligand binding kinetics J Huang, J Chen, SE Chesla, T Yago, P Mehta, RP McEver, C Zhu, ... Journal of Biological Chemistry 279 (43), 44915-44923, 2004 | 148 | 2004 |
Single-molecule fluorescence resonance energy transfer in molecular biology DK Sasmal, LE Pulido, S Kasal, J Huang Nanoscale 8 (48), 19928-19944, 2016 | 137 | 2016 |
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets HL Dugan, CT Stamper, L Li, S Changrob, NW Asby, PJ Halfmann, ... Immunity 54 (6), 1290-1303. e7, 2021 | 136 | 2021 |
Kinetics of MHC-CD8 interaction at the T cell membrane J Huang, LJ Edwards, BD Evavold, C Zhu The Journal of Immunology 179 (11), 7653-7662, 2007 | 128 | 2007 |
Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer J Huang, X Zeng, N Sigal, PJ Lund, LF Su, H Huang, Y Chien, MM Davis Proceedings of the National Academy of Sciences 113 (13), E1890-E1897, 2016 | 114 | 2016 |
Measuring receptor–ligand binding kinetics on cell surfaces: from adhesion frequency to thermal fluctuation methods W Chen, VI Zarnitsyna, KK Sarangapani, J Huang, C Zhu Cellular and molecular bioengineering 1, 276-288, 2008 | 106 | 2008 |
Cyclodextrin‐derived intrinsically bioactive nanoparticles for treatment of acute and chronic inflammatory diseases J Guo, D Li, H Tao, G Li, R Liu, Y Dou, T Jin, L Li, J Huang, H Hu, J Zhang Advanced Materials 31 (46), 1904607, 2019 | 98 | 2019 |
Insights from in situ analysis of TCR–pMHC recognition: response of an interaction network C Zhu, N Jiang, J Huang, VI Zarnitsyna, BD Evavold Immunological reviews 251 (1), 49-64, 2013 | 85 | 2013 |
T-cell mechanobiology: force sensation, potentiation, and translation DL Harrison, Y Fang, J Huang Frontiers in physics 7, 45, 2019 | 76 | 2019 |
Memory in receptor–ligand-mediated cell adhesion VI Zarnitsyna, J Huang, F Zhang, YH Chien, D Leckband, C Zhu Proceedings of the National Academy of Sciences 104 (46), 18037-18042, 2007 | 70 | 2007 |