CAR-NK cells: A promising cellular immunotherapy for cancer G Xie, H Dong, Y Liang, JD Ham, R Rizwan, J Chen EBioMedicine 59, 2020 | 651 | 2020 |
Targeting skeletal endothelium to ameliorate bone loss R Xu, A Yallowitz, A Qin, Z Wu, DY Shin, JM Kim, S Debnath, G Ji, ... Nature medicine 24 (6), 823-833, 2018 | 320 | 2018 |
The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc H Dong, NM Adams, Y Xu, J Cao, DSJ Allan, JR Carlyle, X Chen, JC Sun, ... Nature immunology 20 (7), 865-878, 2019 | 159 | 2019 |
Enhanced efficacy of simultaneous PD-1 and PD-L1 immune checkpoint blockade in high-grade serous ovarian cancer C Wan, MP Keany, H Dong, LF Al-Alem, UM Pandya, S Lazo, K Boehnke, ... Cancer research 81 (1), 158-173, 2021 | 125 | 2021 |
Metabolic influences that regulate dendritic cell function in tumors H Dong, TNJ Bullock Frontiers in immunology 5, 24, 2014 | 98 | 2014 |
Memory-like NK cells armed with a neoepitope-specific CAR exhibit potent activity against NPM1 mutated acute myeloid leukemia H Dong, JD Ham, G Hu, G Xie, J Vergara, Y Liang, A Ali, M Tarannum, ... Proceedings of the National Academy of Sciences 119 (25), e2122379119, 2022 | 88 | 2022 |
Distinct iNKT cell populations use IFNγ or ER stress-induced IL-10 to control adipose tissue homeostasis NM LaMarche, H Kane, AC Kohlgruber, H Dong, L Lynch, MB Brenner Cell metabolism 32 (2), 243-258. e6, 2020 | 74 | 2020 |
CAR-T cells targeting a nucleophosmin neoepitope exhibit potent specific activity in mouse models of acute myeloid leukaemia G Xie, NA Ivica, B Jia, Y Li, H Dong, Y Liang, D Brown, R Romee, J Chen Nature biomedical engineering 5 (5), 399-413, 2021 | 69 | 2021 |
CD27 Stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12–mediated loss of CD8+ T cell memory in the absence of CD4+ T cell help H Dong, NA Franklin, DJ Roberts, H Yagita, MJ Glennie, TNJ Bullock The Journal of Immunology 188 (8), 3829-3838, 2012 | 56 | 2012 |
Engineered memory-like NK cars targeting a neoepitope derived from intracellular NPM1c exhibit potent activity and specificity against acute myeloid leukemia H Dong, G Xie, Y Liang, JD Ham, J Vergara, J Chen, J Ritz, R Romee Blood 136, 3-4, 2020 | 14 | 2020 |
Frontline Science: Late CD27 stimulation promotes IL-7Rα transcriptional re-expression and memory T cell qualities in effector CD8+ T cells H Dong, A Buckner, J Prince, T Bullock Journal of leukocyte biology 106 (5), 1007-1019, 2019 | 13 | 2019 |
CD70 and IFN‐1 selectively induce eomesodermin or T‐bet and synergize to promote CD8+ T‐cell responses H Dong, NA Franklin, SB Ritchea, H Yagita, MJ Glennie, TNJ Bullock European journal of immunology 45 (12), 3289-3301, 2015 | 11 | 2015 |
CAR memory–like NK cells targeting the membrane proximal domain of mesothelin demonstrate promising activity in ovarian cancer M Tarannum, K Dinh, J Vergara, G Birch, YZ Abdulhamid, IE Kaplan, O Ay, ... Science advances 10 (28), eadn0881, 2024 | 6 | 2024 |
Sfrp4 is required to maintain Ctsk-lineage periosteal stem cell niche function R Chen, H Dong, D Raval, D Maridas, S Baroi, K Chen, D Hu, SR Berry, ... Proceedings of the National Academy of Sciences 120 (46), e2312677120, 2023 | 5 | 2023 |
Profiling of natural killer interactions with cancer cells using mass cytometry M Hallisey, J Dennis, EP Gabriel, A Masciarelli, J Chen, C Abrecht, ... Laboratory Investigation 103 (8), 100174, 2023 | 5 | 2023 |
Inhibition of MICA and MICB shedding enhances memory-like NK-cell–mediated cytotoxicity against multiple myeloma S Tahri, S Piccinelli, NK Su, L Lampe, H Dong, J Vergara Cadavid, ... Blood Advances 8 (20), 5365-5370, 2024 | 1 | 2024 |
CAR-T cells targeting a nucleophosmin neoepitope exhibit potent specific activity in mouse models of acute myeloid leukaemia (vol 66, pg 515, 2020) G Xie, NA Ivica, B Jia, Y Li, H Dong, Y Liang, D Brown, R Romee, J Chen NATURE BIOMEDICAL ENGINEERING 5 (1), 124-124, 2021 | 1 | 2021 |
Secreted Frizzled Receptor Protein 4 (Sfrp4) is required for proper response of the periosteal stem/progenitor cells to PTH R Chen, H Dong, D Raval, S Berry, MB Greenblatte, R Baron, F Gori JOURNAL OF BONE AND MINERAL RESEARCH 35, 135-135, 2020 | 1 | 2020 |
IRE1α–XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs BM Barton, F Son, A Verma, SK Bal, Q Tang, R Wang, K Umphred-Wilson, ... Nature Immunology, 1-15, 2025 | | 2025 |
Methods for generating engineered memory-like nk cells and compositions thereof J Chen, J Ritz, R Romee, H Dong, G Xie, JD Ham US Patent App. 17/910,776, 2023 | | 2023 |