Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1 P Luo, D Liu, Q Zhang, F Yang, YK Wong, F Xia, J Zhang, J Chen, Y Tian, ... Acta Pharmaceutica Sinica B 12 (5), 2300-2314, 2022 | 175 | 2022 |
Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect P Luo, Q Zhang, TY Zhong, JY Chen, JZ Zhang, Y Tian, LH Zheng, F Yang, ... Military Medical Research 9 (1), 22, 2022 | 67 | 2022 |
Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis Q Zhang, P Luo, F Xia, H Tang, J Chen, J Zhang, D Liu, Y Zhu, Y Liu, L Gu, ... Cell chemical biology 29 (8), 1248-1259. e6, 2022 | 55 | 2022 |
Scorpion potassium channel-blocking defensin highlights a functional link with neurotoxin L Meng, Z Xie, Q Zhang, Y Li, F Yang, Z Chen, W Li, Z Cao, Y Wu Journal of biological chemistry 291 (13), 7097-7106, 2016 | 50 | 2016 |
Therapeutic potential of a scorpion venom-derived antimicrobial peptide and its homologs against antibiotic-resistant Gram-positive bacteria G Liu, F Yang, F Li, Z Li, Y Lang, B Shen, Y Wu, W Li, PL Harrison, ... Frontiers in microbiology 9, 1159, 2018 | 48 | 2018 |
Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1. 3 channel Z Chen, Y Hu, J Hong, J Hu, W Yang, F Xiang, F Yang, Z Xie, Z Cao, W Li, ... Scientific reports 5 (1), 9881, 2015 | 36 | 2015 |
Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA P Gao, YQ Liu, W Xiao, F Xia, JY Chen, LW Gu, F Yang, LH Zheng, ... Military Medical Research 9 (1), 30, 2022 | 31 | 2022 |
Recent advances in proteome‐wide label‐free target deconvolution for bioactive small molecules J Sun, N Prabhu, J Tang, F Yang, L Jia, J Guo, K Xiao, WL Tam, ... Medicinal Research Reviews 41 (6), 2893-2926, 2021 | 28 | 2021 |
Human α‐defensins are immune‐related Kv1. 3 channel inhibitors: new support for their roles in adaptive immunity Z Xie, J Feng, W Yang, F Xiang, F Yang, Y Zhao, Z Cao, W Li, Z Chen, ... The FASEB Journal 29 (10), 4324-4333, 2015 | 27 | 2015 |
Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice YM Bai, F Yang, P Luo, LL Xie, JH Chen, YD Guan, HC Zhou, TF Xu, ... Military Medical Research 10 (1), 7, 2023 | 25 | 2023 |
Functional characterization of a new non-Kunitz serine protease inhibitor from the scorpion Lychas mucronatus H Liu, J Chen, X Wang, S Yan, Y Xu, M San, W Tang, F Yang, Z Cao, W Li, ... International journal of biological macromolecules 72, 158-162, 2015 | 20 | 2015 |
Thermostable potassium channel-inhibiting neurotoxins in processed scorpion medicinal material revealed by proteomic analysis: Implications of its pharmaceutical basis in … F Yang, D Wang, Y Tong, C Qin, L Yang, F Yu, X Huang, S Liu, Z Cao, ... Journal of proteomics 206, 103435, 2019 | 19 | 2019 |
Expression of recombinant α-toxin BmKM9 from scorpion Buthus martensii Karsch and its functional characterization on sodium channels F Yang, S Liu, Y Zhang, C Qin, L Xu, W Li, Z Cao, W Li, Y Wu Peptides 99, 153-160, 2018 | 15 | 2018 |
Bmk86-p1, a new degradation peptide with desirable thermostability and kv1. 2 channel-specific activity from traditional Chinese scorpion medicinal material C Qin, X Yang, Z Zuo, L Yang, F Yang, Z Cao, Z Chen, Y Wu Toxins 13 (9), 610, 2021 | 8 | 2021 |
Unique Mechanism of the Interaction between Honey Bee Toxin TPNQ and rKir1.1 Potassium Channel Explored by Computational Simulations: Insights into the … J Hu, S Qiu, F Yang, Z Cao, W Li, Y Wu PLoS One 8 (7), e67213, 2013 | 8 | 2013 |
Deep Profiling of the Proteome Dynamics of Pseudomonas aeruginosa Reference Strain PAO1 under Different Growth Conditions M Hou, J Huang, T Jia, Y Guan, F Yang, H Zhou, P Huang, J Wang, ... Journal of Proteome Research 22 (6), 1747-1761, 2023 | 7 | 2023 |
Different pharmacological properties between scorpion toxin BmKcug2 and its degraded analogs highlight the diversity of K+ channel blockers from thermally processed scorpions C Qin, X Wan, S Li, F Yang, L Yang, Z Zuo, Z Cao, Z Chen, Y Wu International Journal of Biological Macromolecules 178, 143-153, 2021 | 7 | 2021 |
Functional characterization of two novel scorpion sodium channel toxins from Lychas mucronatus L Xu, T Li, H Liu, F Yang, S Liang, Z Cao, W Li, Y Wu Toxicon 90, 318-325, 2014 | 7 | 2014 |
Identification of tanshinone I as cap-dependent endonuclease inhibitor with broad-spectrum antiviral effect X He, F Yang, Y Wu, J Lu, X Gao, X Zhu, J Yang, S Liu, G Xiao, X Pan Journal of Virology 97 (10), e00796-23, 2023 | 6 | 2023 |
Mouse β-defensin 3, a defensin inhibitor of both its endogenous and exogenous potassium channels Y Zhang, Y Zhao, H Liu, W Yu, F Yang, W Li, Z Cao, Y Wu Molecules 23 (6), 1489, 2018 | 6 | 2018 |