Complex promoter and coding region β2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness CM Drysdale, DW McGraw, CB Stack, JC Stephens, RS Judson, ... Proceedings of the National Academy of Sciences 97 (19), 10483-10488, 2000 | 1246 | 2000 |
Amino-terminal polymorphisms of the human. Beta. 2-adrenergic receptor impart distinct agonist-promoted regulatory properties SA Green, J Turki, M Innis, SB Liggett Biochemistry 33 (32), 9414-9419, 1994 | 1035 | 1994 |
Mutations in the gene encoding for the 132-adrenergic receptor in normal and asthmatic subjects E Reihsaus, M Innis, N MacIntyre, SB Liggett Am J Respir Cell Mol Biol 8 (3), 334-339, 1993 | 919 | 1993 |
A gain-of-function polymorphism in a G-protein coupling domain of the human β1-adrenergic receptor DA Mason, JD Moore, SA Green, SB Liggett Journal of Biological Chemistry 274 (18), 12670-12674, 1999 | 805 | 1999 |
The Effect of Polymorphisms of the β2-Adrenergic Receptor on the Response to Regular Use of Albuterol in Asthma E Israel, JM Drazen, SB Liggett, HA Boushey, RM Cherniack, ... American journal of respiratory and critical care medicine 162 (1), 75-80, 2000 | 802 | 2000 |
Transgenic Gαq overexpression induces cardiac contractile failure in mice DD D’Angelo, Y Sakata, JN Lorenz, GP Boivin, RA Walsh, SB Liggett, ... Proceedings of the National Academy of Sciences 94 (15), 8121-8126, 1997 | 799 | 1997 |
PKC-α regulates cardiac contractility and propensity toward heart failure JC Braz, K Gregory, A Pathak, W Zhao, B Sahin, R Klevitsky, TF Kimball, ... Nature medicine 10 (3), 248-254, 2004 | 779 | 2004 |
Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial E Israel, VM Chinchilli, JG Ford, HA Boushey, R Cherniack, TJ Craig, ... The Lancet 364 (9444), 1505-1512, 2004 | 748 | 2004 |
Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction DA Deshpande, WCH Wang, EL McIlmoyle, KS Robinett, RM Schillinger, ... Nature medicine 16 (11), 1299-1304, 2010 | 744 | 2010 |
Enhanced Gαq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure JW Adams, Y Sakata, MG Davis, VP Sah, Y Wang, SB Liggett, KR Chien, ... Proceedings of the National Academy of Sciences 95 (17), 10140-10145, 1998 | 712 | 1998 |
Synergistic polymorphisms of β1-and α2C-adrenergic receptors and the risk of congestive heart failure KM Small, LE Wagoner, AM Levin, SLR Kardia, SB Liggett New England Journal of Medicine 347 (15), 1135-1142, 2002 | 676 | 2002 |
A polymorphism of the human beta 2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor. SA Green, G Cole, M Jacinto, M Innis, SB Liggett Journal of Biological Chemistry 268 (31), 23116-23121, 1993 | 610 | 1993 |
Sequencing and analyses of all known human rhinovirus genomes reveal structure and evolution AC Palmenberg, D Spiro, R Kuzmickas, S Wang, A Djikeng, JA Rathe, ... Science 324 (5923), 55-59, 2009 | 600 | 2009 |
Genetic polymorphisms of the beta 2-adrenergic receptor in nocturnal and nonnocturnal asthma. Evidence that Gly16 correlates with the nocturnal phenotype. J Turki, J Pak, SA Green, RJ Martin, SB Liggett The Journal of clinical investigation 95 (4), 1635-1641, 1995 | 582 | 1995 |
Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells. SA Green, J Turki, P Bejarano, IP Hall, SB Liggett American journal of respiratory cell and molecular biology 13 (1), 25-33, 1995 | 579 | 1995 |
Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human K Haghighi, F Kolokathis, L Pater, RA Lynch, M Asahi, AO Gramolini, ... The Journal of clinical investigation 111 (6), 869-876, 2003 | 553 | 2003 |
A polymorphism within a conserved β1-adrenergic receptor motif alters cardiac function and β-blocker response in human heart failure SB Liggett, J Mialet-Perez, S Thaneemit-Chen, SA Weber, SM Greene, ... Proceedings of the National Academy of Sciences 103 (30), 11288-11293, 2006 | 510 | 2006 |
Early and Delayed Consequences of β2-Adrenergic Receptor Overexpression in Mouse Hearts: Critical Role for Expression Level SB Liggett, NM Tepe, JN Lorenz, AM Canning, TD Jantz, S Mitarai, ... circulation 101 (14), 1707-1714, 2000 | 497 | 2000 |
Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic … MG Eason, H Kurose, BD Holt, JR Raymond, SB Liggett Journal of Biological Chemistry 267 (22), 15795-15801, 1992 | 464 | 1992 |
The Ile164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure. SB Liggett, LE Wagoner, LL Craft, RW Hornung, BD Hoit, TC McIntosh, ... The Journal of clinical investigation 102 (8), 1534-1539, 1998 | 459 | 1998 |