Regulation of cellular metabolism by protein lysine acetylation S Zhao, W Xu, W Jiang, W Yu, Y Lin, T Zhang, J Yao, L Zhou, Y Zeng, H Li, ... Science 327 (5968), 1000-1004, 2010 | 2145 | 2010 |
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1α S Zhao, Y Lin, W Xu, W Jiang, Z Zha, P Wang, W Yu, Z Li, L Gong, Y Peng, ... Science 324 (5924), 261-265, 2009 | 1436 | 2009 |
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction S Someya, W Yu, WC Hallows, J Xu, JM Vann, C Leeuwenburgh, ... Cell 143 (5), 802-812, 2010 | 1287 | 2010 |
Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome AS Hebert, KE Dittenhafer-Reed, W Yu, DJ Bailey, ES Selen, ... Molecular Cell, 2012 | 702 | 2012 |
Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice CB Peek, AH Affinati, KM Ramsey, HY Kuo, W Yu, LA Sena, O Ilkayeva, ... Science 342 (6158), 1243417, 2013 | 701 | 2013 |
SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status W Yu, KE Dittenhafer-Reed, JM Denu, W Yu, KE Dittenhafer-Reed, ... Journal of Biological Chemistry 287 (17), 14078-14086, 2012 | 476 | 2012 |
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction WC Hallows, W Yu, BC Smith, MK Devires, JJ Ellinger, S Someya, ... Molecular cell 41 (2), 139-149, 2011 | 445 | 2011 |
Metabolism of amino acids in cancer Z Wei, X Liu, C Cheng, W Yu, P Yi Frontiers in cell and developmental biology 8, 603837, 2021 | 321 | 2021 |
Regulation of Glycolytic Enzyme Phosphoglycerate Mutase-1 by Sirt1 Protein-mediated Deacetylation WC Hallows, W Yu, JM Denu Journal of Biological Chemistry 287 (6), 3850-3858, 2012 | 208 | 2012 |
Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis Z Wei, J Song, G Wang, X Cui, J Zheng, Y Tang, X Chen, J Li, L Cui, ... Nature communications 9 (1), 4468, 2018 | 151 | 2018 |
Generation of acetyllysine antibodies and affinity enrichment of acetylated peptides KL Guan, W Yu, Y Lin, Y Xiong, S Zhao Nature protocols 5 (9), 1583-1595, 2010 | 114 | 2010 |
Loss of SIRT3 provides growth advantage for B cell malignancies W Yu, RA Denu, KA Krautkramer, KM Grindle, DT Yang, F Asimakopoulos, ... Journal of Biological Chemistry 291 (7), 3268-3279, 2016 | 94 | 2016 |
Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage X Cao, C Li, S Xiao, Y Tang, J Huang, S Zhao, X Li, J Li, R Zhang, W Yu Proceedings of the National Academy of Sciences 114 (4), 687-692, 2017 | 78 | 2017 |
LAMB3 promotes tumour progression through the AKT–FOXO3/4 axis and is transcriptionally regulated by the BRD2/acetylated ELK4 complex in colorectal cancer Z Zhu, J Song, Y Guo, Z Huang, X Chen, X Dang, Y Huang, Y Wang, ... Oncogene 39 (24), 4666-4680, 2020 | 65 | 2020 |
Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals W Yu, Y Lin, J Yao, W Huang, Q Lei, Y Xiong, S Zhao, KL Guan Journal of Biological Chemistry 284 (20), 13669-13675, 2009 | 65 | 2009 |
CCBE1 promotes tumor lymphangiogenesis and is negatively regulated by TGFβ signaling in colorectal cancer J Song, W Chen, X Cui, Z Huang, D Wen, Y Yang, W Yu, L Cui, CY Liu Theranostics 10 (5), 2327, 2020 | 57 | 2020 |
Acetylation stabilizes phosphoglycerate dehydrogenase by disrupting the interaction of E3 ligase RNF5 to promote breast tumorigenesis C Wang, X Wan, T Yu, Z Huang, C Shen, Q Qi, S Xiang, X Chen, E Arbely, ... Cell Reports 32 (6), 2020 | 48 | 2020 |
Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell X Wan, C Wang, Z Huang, D Zhou, S Xiang, Q Qi, X Chen, E Arbely, ... Cell Death & Disease 11 (8), 649, 2020 | 48 | 2020 |
CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis Y Guo, Z Zhu, Z Huang, L Cui, W Yu, W Hong, Z Zhou, P Du, CY Liu Nature communications 13 (1), 4995, 2022 | 35 | 2022 |
ELK4 Promotes Colorectal Cancer Progression by Activating the Neoangiogenic Factor LRG1 in a Noncanonical SP1/3‐Dependent Manner Z Zhu, Y Guo, Y Liu, R Ding, Z Huang, W Yu, L Cui, P Du, A Goel, CY Liu Advanced Science 10 (32), 2303378, 2023 | 12 | 2023 |