フォロー
Vijay Kumar Nuthakki
Vijay Kumar Nuthakki
University of Pittsburgh School of Pharmacy
確認したメール アドレス: acsir.res.in
タイトル
引用先
引用先
Discovery of Helminthosporin, an Anthraquinone Isolated from Rumex abyssinicus Jacq as a Dual Cholinesterase Inhibitor
N Augustin, VK Nuthakki, M Abdullaha, QP Hassan, SG Gandhi, ...
ACS omega 5 (3), 1616-1624, 2020
632020
Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors
C Prabhakara, R Godbole, P Sil, S Jahnavi, SJ Gulzar, TS van Zanten, ...
PLoS pathogens 17 (7), e1009706, 2021
582021
Identification of embelin, a 3‐undecyl‐1,4‐benzoquinone from Embelia ribes as a multitargeted anti‐Alzheimer agent
VK Nuthakki, A Sharma, A Kumar, SB Bharate
Drug Development Research 80 (5), 655-665, 2019
552019
Discovery and preclinical development of IIIM-290, an orally active potent cyclin-dependent kinase inhibitor
SB Bharate, V Kumar, SK Jain, MJ Mintoo, SK Guru, VK Nuthakki, ...
Journal of medicinal chemistry 61 (4), 1664-1687, 2018
552018
Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors
VK Nuthakki, R Mudududdla, A Sharma, A Kumar, SB Bharate
Bioorganic Chemistry 90, 103062, 2019
492019
Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase
M Abdullaha, VK Nuthakki, SB Bharate
European Journal of Medicinal Chemistry 207, 112761, 2020
282020
Quantitative phytochemical estimation and evaluation of hepatoprotective activity of methanolic extract of Dendrobium ovatum (L.) Kraenzl. Whole plant against CCl4 induced …
S Ganapaty, M Ramaiah, K Yasaswini, VK Nuthakki, D Harikrishnareddy
Journal of Pharmacognosy and Phytochemistry 2 (3), 113-118, 2013
262013
Malononitrile-activated synthesis and anti-cholinesterase activity of styrylquinoxalin-2 (1 H)-ones
S Mahajan, N Slathia, VK Nuthakki, SB Bharate, KK Kapoor
RSC advances 10 (27), 15966-15975, 2020
202020
Identification of aplysinopsin as a blood-brain barrier permeable scaffold for anti-cholinesterase and anti-BACE-1 activity
VK Nuthakki, RRY Bheemanaboina, SB Bharate
Bioorganic Chemistry 107, 104568, 2021
182021
Design, synthesis, and pharmacological evaluation of embelin–aryl/alkyl amine hybrids as orally bioavailable blood–brain barrier permeable multitargeted agents with therapeutic …
VK Nuthakki, S Choudhary, CN Reddy, S Bhatt, A Jamwal, A Jotshi, ...
ACS chemical neuroscience 14 (6), 1193-1219, 2023
172023
Identification of plant-based multitargeted leads for Alzheimer's disease: In-vitro and in-vivo validation of Woodfordia fruticosa (L.) Kurz
R Raghuvanshi, VK Nuthakki, L Singh, B Singh, SS Bharate, R Bhatti, ...
Phytomedicine 91, 153659, 2021
172021
Biotransformation of chrysin to baicalein: selective C6-hydroxylation of 5, 7-dihydroxyflavone using whole yeast cells stably expressing human CYP1A1 enzyme
IS Williams, S Chib, VK Nuthakki, L Gatchie, P Joshi, NA Narkhede, ...
Journal of agricultural and food chemistry 65 (34), 7440-7446, 2017
152017
Design, synthesis, and structure–activity relationship of caffeine‐based triazoles as dual AChE and BACE‐1 inhibitors
M Sharma, A Sharma, VK Nuthakki, S Bhatt, U Nandi, SB Bharate
Drug Development Research 83 (8), 1803-1821, 2022
142022
Role of basic aminoalkyl chains in the lead optimization of Indoloquinoline alkaloids
VK Nuthakki, R Mudududdla, SB Bharate
European Journal of Medicinal Chemistry 227, 113938, 2022
142022
A Coumarin− Donepezil Hybrid as a Blood− Brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications, and Biological Evaluation of Natural Coumarins
A Sharma, VK Nuthakki, S Gairola, B Singh, SB Bharate
ChemMedChem 17 (18), e202200300, 2022
92022
Niclosamide inhibits SARS-CoV2 entry by blocking internalization through pH-dependent CLIC/GEEC endocytic pathway
C Prabhakara, R Godbole, P Sil, S Jahnavi, TS van Zanten, D Sheth, ...
bioRxiv, 2020.12. 16.422529, 2020
92020
Niclosamide inhibits SARS-CoV2 entry by blocking internalization through pH-dependent CLIC
C Prabhakara, R Godbole, P Sil, S Jahnavi, TS van Zanten, D Sheth, ...
GEEC endocytic pathway. bioRxiv 2020 (16.422529), 2020
82020
Design, synthesis, and pharmacological evaluation of indole-piperidine amides as Blood− brain barrier permeable dual cholinesterase and β-secretase inhibitors
R Banoo, VK Nuthakki, BN Wadje, A Sharma, SB Bharate
European Journal of Medicinal Chemistry 266, 116131, 2024
62024
Blood–brain barrier permeable benzylpiperidin‐4‐yl‐linked benzylamino benzamides as dual cholinesterase inhibitors
R Banoo, VK Nuthakki, M Abdullaha, M Sharma, SB Bharate
Drug Development Research 83 (8), 1791-1802, 2022
62022
Discovery of blood-brain barrier permeable and orally bioavailable caffeine-based amide derivatives as acetylcholinesterase inhibitors
M Sharma, A Sharma, S Thakur, VK Nuthakki, A Jamwal, U Nandi, ...
Bioorganic Chemistry 139, 106719, 2023
52023
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