Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats KK Lemberg, VK Kontinen, AO Siiskonen, KM Viljakka, ... Anesthesiology 105 (4), 801-812, 2006 | 97 | 2006 |
Controlling azobenzene photoswitching through combined ortho-fluorination and-amination Z Ahmed, A Siiskonen, M Virkki, A Priimagi Chemical communications 53 (93), 12520-12523, 2017 | 82 | 2017 |
Inhibitory effect of the natural product betulin and its derivatives against the intracellular bacterium Chlamydia pneumoniae O Salin, S Alakurtti, L Pohjala, A Siiskonen, V Maass, M Maass, ... Biochemical pharmacology 80 (8), 1141-1151, 2010 | 74 | 2010 |
Benchmarking DFT methods with small basis sets for the calculation of halogen-bond strengths A Siiskonen, A Priimagi Journal of molecular modeling 23 (2), 50, 2017 | 72 | 2017 |
Design and Synthesis of 2-Arylbenzimidazoles and Evaluation of Their Inhibitory Effect against Chlamydia pneumoniae L Keurulainen, O Salin, A Siiskonen, JM Kern, J Alvesalo, P Kiuru, ... Journal of medicinal chemistry 53 (21), 7664-7674, 2010 | 69 | 2010 |
Efficient light-induced phase transitions in halogen-bonded liquid crystals F Fernandez-Palacio, M Poutanen, M Saccone, A Siiskonen, G Terraneo, ... Chemistry of Materials 28 (22), 8314-8321, 2016 | 54 | 2016 |
Similarity based virtual screening: a tool for targeted library design JKO Alvesalo, A Siiskonen, MJ Vainio, PSM Tammela, PM Vuorela Journal of medicinal chemistry 49 (7), 2353-2356, 2006 | 54 | 2006 |
Pharmacological characterization of noroxymorphone as a new opioid for spinal analgesia KK Lemberg, AO Siiskonen, VK Kontinen, JT Yli-Kauhaluoma, EA Kalso Anesthesia & Analgesia 106 (2), 463-470, 2008 | 43 | 2008 |
Microplate screening assay to identify inhibitors of human catechol-O-methyltransferase M Kurkela, A Siiskonen, M Finel, P Tammela, J Taskinen, P Vuorela Analytical biochemistry 331 (1), 198-200, 2004 | 36 | 2004 |
ortho-Fluorination of azophenols increases the mesophase stability of photoresponsive hydrogen-bonded liquid crystals M Saccone, K Kuntze, Z Ahmed, A Siiskonen, M Giese, A Priimagi Journal of Materials Chemistry C 6 (37), 9958-9963, 2018 | 35 | 2018 |
Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17 I Bichlmaier, A Siiskonen, M Finel, J Yli-Kauhaluoma Journal of medicinal chemistry 49 (5), 1818-1827, 2006 | 34 | 2006 |
Synthesis and biological evaluation of 2-arylbenzimidazoles targeting Leishmania donovani L Keurulainen, A Siiskonen, A Nasereddin, D Kopelyanskiy, ... Bioorganic & Medicinal Chemistry Letters 25 (9), 1933-1937, 2015 | 26 | 2015 |
Halogen-bond driven self-assembly of triangular macrocycles PMJ Szell, A Siiskonen, L Catalano, G Cavallo, G Terraneo, A Priimagi, ... New Journal of Chemistry 42 (13), 10467-10471, 2018 | 23 | 2018 |
Supramolecular control of liquid crystals by doping with halogen-bonding dyes J Vapaavuori, A Siiskonen, V Dichiarante, A Forni, M Saccone, T Pilati, ... RSC advances 7 (64), 40237-40242, 2017 | 19 | 2017 |
Isoform-selective inhibition of the human UDP-glucuronosyltransferase 2B7 by isolongifolol derivatives I Bichlmaier, M Kurkela, T Joshi, A Siiskonen, T Rüffer, H Lang, ... Journal of medicinal chemistry 50 (11), 2655-2664, 2007 | 19 | 2007 |
A Developability-Focused Optimization Approach Allows Identification of in Vivo Fast-Acting Antimalarials: N-[3-[(Benzimidazol-2-yl)amino]propyl]amides L Keurulainen, M Vahermo, M Puente-Felipe, E Sandoval-Izquierdo, ... Journal of Medicinal Chemistry 58 (11), 4573-4580, 2015 | 17 | 2015 |
Azobenzene photoswitching with near-infrared light mediated by molecular oxygen K Kuntze, J Isokuortti, A Siiskonen, N Durandin, T Laaksonen, A Priimagi The Journal of Physical Chemistry B 125 (45), 12568-12573, 2021 | 14 | 2021 |
Halogen bonding stabilizes a cis-azobenzene derivative in the solid state: a crystallographic study M Saccone, A Siiskonen, F Fernandez-Palacio, A Priimagi, G Terraneo, ... Acta Crystallographica Section B: Structural Science, Crystal Engineering …, 2017 | 14 | 2017 |
Eudismic analysis of tricyclic sesquiterpenoid alcohols: Lead structures for the design of potent inhibitors of the human UDP-glucuronosyltransferase 2B7 I Bichlmaier, M Kurkela, A Siiskonen, M Finel, J Yli-Kauhaluoma Bioorganic chemistry 35 (5), 386-400, 2007 | 11 | 2007 |
Oxycodone’s mechanism of action and potency differences after spinal and systemic routes of administration KK Lemberg, ER Korpi, AO Siiskonen, JT Yli-Kauhaluoma, VK Kontinen, ... The Journal of the American Society of Anesthesiologists 106 (5), 1064-1065, 2007 | 11 | 2007 |