Gene essentiality and synthetic lethality in haploid human cells VA Blomen, P Májek, LT Jae, JW Bigenzahn, J Nieuwenhuis, J Staring, ... Science 350 (6264), 1092-1096, 2015 | 931 | 2015 |
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators R Mezzadra, C Sun, LT Jae, R Gomez-Eerland, E De Vries, W Wu, ... Nature 549 (7670), 106-110, 2017 | 640 | 2017 |
An essential receptor for adeno-associated virus infection S Pillay, NL Meyer, AS Puschnik, O Davulcu, J Diep, Y Ishikawa, LT Jae, ... Nature 530 (7588), 108-112, 2016 | 584 | 2016 |
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol E Fessler, EM Eckl, S Schmitt, IA Mancilla, MF Meyer-Bender, M Hanf, ... Nature 579 (7799), 433-437, 2020 | 395 | 2020 |
Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry LT Jae, M Raaben, M Riemersma, E van Beusekom, VA Blomen, A Velds, ... Science 340 (6131), 479-483, 2013 | 310 | 2013 |
Lassa virus entry requires a trigger-induced receptor switch LT Jae, M Raaben, AS Herbert, AI Kuehne, AS Wirchnianski, TK Soh, ... Science 344 (6191), 1506-1510, 2014 | 303 | 2014 |
The acid-sensitive potassium channel TASK-1 in rat cardiac muscle C Putzke, K Wemhöner, FB Sachse, S Rinné, G Schlichthörl, XT Li, L Jaé, ... Cardiovascular research 75 (1), 59-68, 2007 | 190 | 2007 |
Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling. BTR Brockmann M, Blomen VA, Nieuwenhuis J, Stickel E, Raaben M, Bleijerveld ... Nature, 2017 | 143 | 2017 |
NRP2 and CD63 are host factors for Lujo virus cell entry M Raaben, LT Jae, AS Herbert, AI Kuehne, SH Stubbs, Y Chou, ... Cell host & microbe 22 (5), 688-696. e5, 2017 | 135 | 2017 |
BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity AM Heijink, F Talens, LT Jae, SE van Gijn, RSN Fehrmann, ... Nature Communications 10 (1), 100, 2019 | 132 | 2019 |
A haploid genetic screen identifies heparan sulfate proteoglycans supporting Rift Valley fever virus infection AM Riblett, VA Blomen, LT Jae, LA Altamura, RW Doms, ... Journal of Virology 90 (3), 1414-1423, 2016 | 128 | 2016 |
Protocadherin-1 is essential for cell entry by New World hantaviruses RK Jangra, AS Herbert, R Li, LT Jae, LM Kleinfelter, MM Slough, ... Nature 563 (7732), 559-563, 2018 | 123 | 2018 |
Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion LM Kleinfelter, RK Jangra, LT Jae, AS Herbert, E Mittler, KM Stiles, ... MBio 6 (4), 10.1128/mbio. 00801-15, 2015 | 116 | 2015 |
Enterovirus D68 receptor requirements unveiled by haploid genetics J Baggen, HJ Thibaut, J Staring, LT Jae, Y Liu, H Guo, JJ Slager, ... Proceedings of the National Academy of Sciences 113 (5), 1399-1404, 2016 | 113 | 2016 |
Human ISPD is a cytidyltransferase required for dystroglycan O-mannosylation M Riemersma, DS Froese, W van Tol, UF Engelke, J Kopec, ... Chemistry & biology 22 (12), 1643-1652, 2015 | 82 | 2015 |
DNA structure-specific cleavage of DNA-protein crosslinks by the SPRTN protease HK Reinking, HS Kang, MJ Götz, HY Li, A Kieser, S Zhao, AC Acampora, ... Molecular cell 80 (1), 102-113. e6, 2020 | 64 | 2020 |
Sensing, signaling and surviving mitochondrial stress EM Eckl, O Ziegemann, L Krumwiede, E Fessler, LT Jae Cellular and Molecular Life Sciences 78, 5925-5951, 2021 | 62 | 2021 |
DELE1 tracks perturbed protein import and processing in human mitochondria E Fessler, L Krumwiede, LT Jae Nature Communications 13 (1), 1853, 2022 | 59 | 2022 |
Emerging intracellular receptors for hemorrhagic fever viruses LT Jae, TR Brummelkamp Trends in microbiology 23 (7), 392-400, 2015 | 52 | 2015 |
OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy MK Shammas, X Huang, BP Wu, E Fessler, IY Song, NP Randolph, Y Li, ... The Journal of Clinical Investigation 132 (14), 2022 | 51 | 2022 |