| Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans VE Brunt, RA Gioscia-Ryan, AG Casso, NS VanDongen, BP Ziemba, ... Hypertension 76 (1), 101-112, 2020 | 215 | 2020 |
| Gut microbiome-derived metabolite trimethylamine N-oxide induces aortic stiffening and increases systolic blood pressure with aging in mice and humans VE Brunt, AG Casso, RA Gioscia-Ryan, ZJ Sapinsley, BP Ziemba, ... Hypertension 78 (2), 499-511, 2021 | 74 | 2021 |
| Apigenin restores endothelial function by ameliorating oxidative stress, reverses aortic stiffening, and mitigates vascular inflammation with aging ZS Clayton, DA Hutton, VE Brunt, NS VanDongen, BP Ziemba, AG Casso, ... American Journal of Physiology-Heart and Circulatory Physiology 321 (1 …, 2021 | 59 | 2021 |
| Cellular senescence contributes to large elastic artery stiffening and endothelial dysfunction with aging: amelioration with senolytic treatment ZS Clayton, MJ Rossman, SA Mahoney, R Venkatasubramanian, ... Hypertension 80 (10), 2072-2087, 2023 | 35 | 2023 |
| Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence SA Mahoney, R Venkatasubramanian, MA Darrah, KR Ludwig, ... Aging Cell 23 (3), e14060, 2024 | 34 | 2024 |
| Tumor Necrosis Factor Alpha-Mediated Inflammation and Remodeling of the Extracellular Matrix Underlies Aortic Stiffening Induced by the Common Chemotherapeutic Agent Doxorubicin ZS Clayton, VE Brunt, DA Hutton, AG Casso, BP Ziemba, S Melov, ... Hypertension 77 (5), 1581-1590, 2021 | 32 | 2021 |
| Initiation of 3,3‐dimethyl‐1‐butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice AG Casso, NS VanDongen, RA Gioscia‐Ryan, ZS Clayton, NT Greenberg, ... The Journal of Physiology 600 (21), 4633-4651, 2022 | 21 | 2022 |
| Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in mice VE Brunt, NT Greenberg, ZJ Sapinsley, AG Casso, JJ Richey, ... Journal of Applied Physiology 133 (4), 798-813, 2022 | 16 | 2022 |
| Late‐Life Treatment with the Senolytic ABT‐263 Reverses Aortic Stiffening and Improves Endothelial Function with Aging S Mahoney, D Hutton, M Rossman, V Brunt, N VanDongen, A Casso, ... The FASEB Journal 35, 2021 | 11 | 2021 |
| Female C57BL/6N mice are a viable model of aortic aging in women AG Longtine, R Venkatasubramanian, MC Zigler, AJ Lindquist, ... American Journal of Physiology-Heart and Circulatory Physiology 324 (6 …, 2023 | 8 | 2023 |
| Cellular senescence mediates doxorubicin‐induced arterial dysfunction via activation of mitochondrial oxidative stress and the mammalian target of rapamycin D Hutton, V Brunt, S Mahoney, A Casso, N Greenberg, N VanDongen, ... The FASEB Journal 35, 2021 | 8 | 2021 |
| The gut microbiome as a modulator of arterial function and age-related arterial dysfunction AG Longtine, NT Greenberg, Y Bernaldo de Quirós, VE Brunt American Journal of Physiology-Heart and Circulatory Physiology 326 (4 …, 2024 | 5 | 2024 |
| Fisetin supplementation improves age-related vascular endothelial function by suppressing cellular senescence and mitochondrial oxidative stress SA Mahoney, R Venkatasubramanian, M Rossman, N VanDongen, ... FASEB J 36, 2022 | 5 | 2022 |
| Transfer of Young Gut Microbiota Ameliorates Age‐and Western‐Style Diet‐Related Vascular Endothelial Dysfunction in Mice NS VanDongen, RA Gioscia‐Ryan, JN Frye, AG Casso, MC Zigler, ... The FASEB Journal 33 (S1), 828.16-828.16, 2019 | 5 | 2019 |
| Oral Supplementation with the Short-Chain Fatty Acid Acetate Ameliorates Age-Related Aortic Stiffening in Mice A Lindquist, N Greenberg, A Longtine, N VanDongen, S Mahoney, ... Physiology 38 (S1), 5732615, 2023 | 4 | 2023 |
| Consumption of a high-fiber diet improves systolic blood pressure and vascular endothelial function and may reduce oxidative stress in middle-aged to older adults AG Casso Age (years) 69, 5, 2022 | 4 | 2022 |
| Changes in gut microbiome composition with healthy aging in humans: Links to vascular endothelial function FASEB J 36 (1), 2022 | 4* | 2022 |
| Cellular Senescence and the Associated Secretome Contribute to Age‐Related Vascular Dysfunction R Venkatasubramanian, SA Mahoney, MJ Rossman, DA Hutton, VE Brunt, ... The FASEB Journal 36, 2022 | 4 | 2022 |
| The short-chain fatty acid acetate improves age-associated vascular endothelial dysfunction N Greenberg, A Casso, A Lindquist, N VanDongen, S Mahoney, Z Clayton, ... Physiology 38 (S1), 5726704, 2023 | 2 | 2023 |
| Age-related Aortic Stiffness Can Be Transferred and Ameliorated via Fecal Microbiota Transplant in Mice. N Greenberg, N VanDongen, R Gioscia-Ryan, A Casso, D Hutton, ... Innovation in Aging 5 (Supplement_1), 823-824, 2021 | 2 | 2021 |