In vitro and ex vivo models in inhalation biopharmaceutical research—advances, challenges and future perspectives MA Selo, JA Sake, KJ Kim, C Ehrhardt Advanced Drug Delivery Reviews 177, 113862, 2021 | 61 | 2021 |
Organic cation transporters in the lung—current and emerging (patho) physiological and pharmacological concepts MA Selo, JA Sake, C Ehrhardt, JJ Salomon International Journal of Molecular Sciences 21 (23), 9168, 2020 | 46 | 2020 |
Assessing the activity of multidrug resistance–associated protein 1 at the lung epithelial barrier S Mairinger, JA Sake, IH Lozano, T Filip, M Sauberer, J Stanek, T Wanek, ... Journal of Nuclear Medicine 61 (11), 1650-1657, 2020 | 22 | 2020 |
Tobacco Smoke and Inhaled Drugs Alter Expression and Activity of Multidrug Resistance-Associated Protein-1 (MRP1) in Human Distal Lung Epithelial Cells in vitro MA Selo, AS Delmas, L Springer, V Zoufal, JA Sake, CG Clerkin, H Huwer, ... Frontiers in bioengineering and biotechnology 8, 1030, 2020 | 18 | 2020 |
PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats I Hernández-Lozano, S Mairinger, T Filip, M Sauberer, T Wanek, J Stanek, ... Journal of Controlled Release 342, 44-52, 2022 | 16 | 2022 |
Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats S Mairinger, I Hernández-Lozano, T Filip, M Sauberer, M Löbsch, ... Journal of Controlled Release 349, 109-117, 2022 | 11 | 2022 |
In vitro antioxidant and wound healing properties of baru nut extract (Dipteryx alata Vog.) in pulmonary epithelial cells for therapeutic application in chronic … JC Coco, JA Ataide, JA Sake, EB Tambourgi, C Ehrhardt, PG Mazzola Natural Product Research 36 (17), 4469-4475, 2022 | 9 | 2022 |
Knockout of ABCC1 in NCI-H441 cells reveals CF to be a suboptimal substrate to study MRP1 activity in organotypic in vitro models JA Sake, MA Selo, L Burtnyak, HE Dähnhardt, C Helbet, S Mairinger, ... European Journal of Pharmaceutical Sciences 181, 106364, 2023 | 5 | 2023 |
Fyn-kinase and caveolin-1 in the alveolar epithelial junctional adherence complex contribute to the early stages of pulmonary fibrosis V Menzel, M Ziegler, N Hante, JA Sake, MJ Santos-Martinez, C Ehrhardt, ... European Journal of Pharmaceutical Sciences 175, 106236, 2022 | 4 | 2022 |
The activity of a Ga (III) catecholate complex against Aspergillus fumigatus in conditions mimicking cystic fibrosis lung and inhaled formulations for its pulmonary administration B Grassiri, S Esin, ME Piatek, LM O’Ferrall, JA Sake, DM Griffith, ... International Journal of Pharmaceutics 667, 124871, 2024 | | 2024 |
EXPLORING MEMBRANE TRANSPORTERS IN LUNG EPITHELIAL CELLS: DRUG–TRANSPORTER INTERACTION ANALYSES IN DIFFERENT IN VITRO MODELS JA Sake School of Pharmacy and Pharmaceutical Sciences, Trinity College, Dublin 2 …, 2023 | | 2023 |