| GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ... Nature communications 12 (1), 4860, 2021 | 191 | 2021 |
| Antibiotic-induced depletion of anti-inflammatory clostridia is associated with the development of graft-versus-host disease in pediatric stem cell transplantation patients TR Simms-Waldrip, G Sunkersett, LA Coughlin, MR Savani, C Arana, ... Biology of Blood and Marrow Transplantation 23 (5), 820-829, 2017 | 162 | 2017 |
| De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma DD Shi, MR Savani, MM Levitt, AC Wang, JE Endress, CE Bird, J Buehler, ... Cancer cell 40 (9), 939-956. e16, 2022 | 84 | 2022 |
| Cytosine deaminase APOBEC3A sensitizes leukemia cells to inhibition of the DNA replication checkpoint AM Green, K Budagyan, KE Hayer, MA Reed, MR Savani, GB Wertheim, ... Cancer research 77 (17), 4579-4588, 2017 | 65 | 2017 |
| Establishment of patient-derived organoid models of lower-grade glioma KG Abdullah, CE Bird, JD Buehler, LC Gattie, MR Savani, AC Sternisha, ... Neuro-oncology 24 (4), 612-623, 2022 | 64 | 2022 |
| A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma S Pal, JP Kaplan, H Nguyen, SA Stopka, MR Savani, MS Regan, ... Cancer Cell 40 (9), 957-972. e10, 2022 | 57 | 2022 |
| Emerging roles of nucleotide metabolism in cancer DD Shi, MR Savani, KG Abdullah, SK McBrayer Trends in cancer 9 (8), 624-635, 2023 | 26 | 2023 |
| Antitumor activity of a mitochondrial-targeted HSP90 inhibitor in gliomas S Wei, D Yin, S Yu, X Lin, MR Savani, K Du, Y Ku, D Wu, S Li, H Liu, ... Clinical Cancer Research 28 (10), 2180-2195, 2022 | 20 | 2022 |
| A modified nucleoside 6-Thio-2′-deoxyguanosine exhibits antitumor activity in gliomas S Yu, S Wei, M Savani, X Lin, K Du, I Mender, S Siteni, T Vasilopoulos, ... Clinical Cancer Research 27 (24), 6800-6814, 2021 | 20 | 2021 |
| Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity MJ Wu, H Kondo, AV Kammula, L Shi, Y Xiao, S Dhiab, Q Xu, CJ Slater, ... Science 385 (6705), eadl6173, 2024 | 16 | 2024 |
| Amplifying the noise: oncometabolites mask an epigenetic signal of DNA damage MR Savani, KG Abdullah, SK McBrayer Molecular cell 79 (3), 368-370, 2020 | 7 | 2020 |
| The role of gut microbiota in the development of intestinal GVHD T Simms-Waldrip, M Meir, D Fan, L Coughlin, M Savani, T Watt, V Aquino, ... Biology of Blood and Marrow Transplantation 20 (2), S55-S56, 2014 | 7 | 2014 |
| Antibiotic-induced depletion of Anti-Inflammatory Clostridia is associated with the development of GVHD in pediatric stem cell transplant patients TR Simms-Waldrip, G Sunkersett, LA Coughlin, MR Savani, C Arana, ... PEDIATRIC BLOOD & CANCER 64, S99-S99, 2017 | 4 | 2017 |
| Human plasma-like medium facilitates metabolic tracing and enables upregulation of immune signaling pathways in glioblastoma explants M El Shami, MR Savani, LC Gattie, B Smith, WH Hicks, JN Rich, ... bioRxiv, 2023 | 3 | 2023 |
| Semi-automated computational assessment of cancer organoid viability using rapid live-cell microscopy JD Buehler, CE Bird, MR Savani, LC Gattie, WH Hicks, MM Levitt, ... Cancer Informatics 21, 11769351221100754, 2022 | 2 | 2022 |
| Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis R Nair, AH Vu, AK Freer, KS Bhatia, D Wang, MR Savani, SM Matulis, ... Blood, 2024 | | 2024 |
| Human Plasma-Like Medium Activates Immune Elements in Glioma M El Shami, M Savani, WH Hicks, L Gattie, S McBrayer, KG Abdullah Neurosurgery 70 (Supplement_1), 201, 2024 | | 2024 |
| TMET-07. MOLECULAR MECHANISM OF EXQUISITE SENSITIVITY OF DIFFUSE MIDLINE GLIOMA TO DE NOVO PYRIMIDINE BIOSYNTHESIS S Pal, M Savani, J Kaplan, SSA Stopka, H Nguyen, M Regan, N Agar, ... Neuro-Oncology 24 (Suppl 7), vii262, 2022 | | 2022 |
| A METHOD FOR EX VIVO STABLE ISOTOPE TRACING IN SURGICALLY EXPLANTED GLIOMA ORGANOIDS M El Shami, M Savani, L Gattie, W Hicks, T Richardson, S McBrayer, ... NEURO-ONCOLOGY 24, 267-268, 2022 | | 2022 |
| TMOD-06. CREATION OF PATIENT-DERIVED LOWER GRADE GLIOMA ORGANOID MODELS FOR PERSONALIZED TREATMENT RESPONSE ASSESSMENT K Abdullah, J Buehler, C Bird, M Savani, A Sternisha, M Levitt, ... Neuro-Oncology 23 (Suppl 6), vi216, 2021 | | 2021 |
