Homotypic fusion of ER membranes requires the dynamin-like GTPase atlastin G Orso, D Pendin, S Liu, J Tosetto, TJ Moss, JE Faust, M Micaroni, ... Nature 460 (7258), 978-983, 2009 | 515 | 2009 |
The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function N Trotta, G Orso, MG Rossetto, A Daga, K Broadie Current biology 14 (13), 1135-1147, 2004 | 291 | 2004 |
Boswellia serrata preserves intestinal epithelial barrier from oxidative and inflammatory damage D Catanzaro, S Rancan, G Orso, S Dall’Acqua, P Brun, MC Giron, ... PloS one 10 (5), e0125375, 2015 | 149 | 2015 |
Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine G Orso, A Martinuzzi, MG Rossetto, E Sartori, M Feany, A Daga The Journal of clinical investigation 115 (11), 3026-3034, 2005 | 134 | 2005 |
Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death D Catanzaro, E Gaude, G Orso, C Giordano, G Guzzo, A Rasola, ... Oncotarget 6 (30), 30102, 2015 | 133 | 2015 |
Antibiotic‐induced dysbiosis of the microbiota impairs gut neuromuscular function in juvenile mice V Caputi, I Marsilio, V Filpa, S Cerantola, G Orso, M Bistoletti, ... British journal of pharmacology 174 (20), 3623-3639, 2017 | 122 | 2017 |
Spastin binds to lipid droplets and affects lipid metabolism C Papadopoulos, G Orso, G Mancuso, M Herholz, S Gumeni, N Tadepalle, ... PLoS genetics 11 (4), e1005149, 2015 | 112 | 2015 |
Cardiac glycoside ouabain induces autophagic cell death in non-small cell lung cancer cells via a JNK-dependent decrease of Bcl-2 A Trenti, P Grumati, F Cusinato, G Orso, P Bonaldo, L Trevisi Biochemical pharmacology 89 (2), 197-209, 2014 | 107 | 2014 |
Cholesterol metabolic reprogramming in cancer and its pharmacological modulation as therapeutic strategy I Giacomini, F Gianfanti, MA Desbats, G Orso, M Berretta, T Prayer-Galetti, ... Frontiers in oncology 11, 682911, 2021 | 86 | 2021 |
The fine tuning of Drp1-dependent mitochondrial remodeling and autophagy controls neuronal differentiation C Vantaggiato, M Castelli, M Giovarelli, G Orso, MT Bassi, E Clementi, ... Frontiers in Cellular Neuroscience 13, 120, 2019 | 65 | 2019 |
Toll-like receptor 4 modulates small intestine neuromuscular function through nitrergic and purinergic pathways V Caputi, I Marsilio, S Cerantola, M Roozfarakh, I Lante, F Galuppini, ... Frontiers in pharmacology 8, 350, 2017 | 60 | 2017 |
Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment D Scheggia, R Mastrogiacomo, M Mereu, S Sannino, RE Straub, ... Nature communications 9 (1), 2265, 2018 | 53 | 2018 |
Involvement of the P2X7 purinergic receptor in colonic motor dysfunction associated with bowel inflammation in rats L Antonioli, MC Giron, R Colucci, C Pellegrini, D Sacco, V Caputi, G Orso, ... PloS one 9 (12), e116253, 2014 | 51 | 2014 |
Eight novel mutations in SPG4 in a large sample of patients with hereditary spastic paraplegia F Crippa, C Panzeri, A Martinuzzi, A Arnoldi, F Redaelli, A Tonelli, ... Archives of neurology 63 (5), 750-755, 2006 | 51 | 2006 |
Antipsychotics promote metabolic disorders disrupting cellular lipid metabolism and trafficking C Vantaggiato, E Panzeri, A Citterio, G Orso, M Pozzi Trends in Endocrinology & Metabolism 30 (3), 189-210, 2019 | 50 | 2019 |
Colonic motor dysfunctions in a mouse model of high-fat diet-induced obesity: an involvement of A2B adenosine receptors L Antonioli, C Pellegrini, M Fornai, E Tirotta, D Gentile, L Benvenuti, ... Purinergic Signalling 13, 497-510, 2017 | 50 | 2017 |
Western diet-induced metabolic alterations affect circulating markers of liver function before the development of steatosis D Gabbia, M Roverso, M Guido, D Sacchi, M Scaffidi, M Carrara, G Orso, ... Nutrients 11 (7), 1602, 2019 | 45 | 2019 |
Interplay between colonic inflammation and tachykininergic pathways in the onset of colonic dysmotility in a mouse model of diet-induced obesity L Antonioli, V Caputi, M Fornai, C Pellegrini, D Gentile, MC Giron, G Orso, ... International Journal of Obesity 43 (2), 331-343, 2019 | 38 | 2019 |
Serenoa repens and Urtica dioica Fixed Combination: In-Vitro Validation of a Therapy for Benign Prostatic Hyperplasia (BPH) M Saponaro, I Giacomini, G Morandin, V Cocetta, E Ragazzi, G Orso, ... International Journal of Molecular Sciences 21 (23), 9178, 2020 | 30 | 2020 |
‘Nature-inspired’drug–protein complexes as inhibitors of Aβ aggregation M Bose, JE Gestwicki, V Devasthali, GR Crabtree, IA Graef Biochemical Society Transactions 33 (4), 543-547, 2005 | 25 | 2005 |