Neurodevelopmental disorders, like cancer, are connected to impaired chromatin remodelers, PI3K/mTOR, and PAK1-regulated MAPK R Nussinov, BR Yavuz, MK Arici, HC Demirel, M Zhang, Y Liu, CJ Tsai, ... Biophysical Reviews 15 (2), 163-181, 2023 | 29 | 2023 |
Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome BR Yavuz, MK Arici, HC Demirel, CJ Tsai, H Jang, R Nussinov, ... NPJ genomic medicine 8 (1), 37, 2023 | 23 | 2023 |
Mechanism of activation and the rewired network: new drug design concepts R Nussinov, M Zhang, R Maloney, CJ Tsai, BR Yavuz, N Tuncbag, H Jang Medicinal research reviews 42 (2), 770-799, 2022 | 22 | 2022 |
Pan-cancer clinical impact of latent drivers from double mutations BR Yavuz, CJ Tsai, R Nussinov, N Tuncbag Communications Biology 6 (1), 202, 2023 | 13 | 2023 |
Anticancer drugs: How to select small molecule combinations? R Nussinov, BR Yavuz, H Jang Trends in Pharmacological Sciences, 2024 | 9 | 2024 |
Neurodevelopmental disorders, like cancer, are connected to impaired chromatin remodelers, PI3K/mTOR, and PAK1-regulated MAPK. Biophys Rev 15: 163–181 R Nussinov, BR Yavuz, MK Arici, HC Demirel, M Zhang, Y Liu, CJ Tsai, ... | 7 | 2023 |
Cancer and neurodevelopmental disorders: multi-scale reasoning and computational guide R Nussinov, BR Yavuz, HC Demirel, MK Arici, H Jang, N Tuncbag Frontiers in Cell and Developmental Biology 12, 1376639, 2024 | 4 | 2024 |
Single cell spatial biology over developmental time can decipher pediatric brain pathologies R Nussinov, BR Yavuz, H Jang Neurobiology of Disease, 106597, 2024 | 3 | 2024 |
Discovery of latent drivers from double mutations in pan-cancer data reveal their clinical impact BR Yavuz, CJ Tsai, R Nussinov, N Tuncbag bioRxiv, 2021.04. 02.438239, 2021 | 2 | 2021 |
Anticancer Target Combinations: Network-Informed Signaling-Based Approach to Discovery BR Yavuz, H Jang, R Nussinov bioRxiv, 2024.10. 11.617918, 2024 | 1 | 2024 |
Co-occurring Mutations in Different Genes Can Fuel Oncogenic Signaling and Serve as Metastatic Tumor Markers BR Yavuz, U Sahin, H Jang, R Nussinov, N Tuncbag bioRxiv, 2024.05. 01.592039, 2024 | | 2024 |
A COMPREHENSIVE ANALYSIS OF MUTATIONS IN CANCERS AND NEURODEVELOPMENTAL DISORDERS BR Yavuz Middle East Technical University, 2023 | | 2023 |