A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories D Placido, B Yuan, JX Hjaltelin, C Zheng, AD Haue, PJ Chmura, C Yuan, ... Nature medicine 29 (5), 1113-1122, 2023 | 170 | 2023 |
MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27 C Zheng, Z Lin, ZJ Zhao, Y Yang, H Niu, X Shen Journal of Biological Chemistry 281 (48), 37215-37226, 2006 | 125 | 2006 |
Genotype-phenotype correlation in combined deficiency of factor V and factor VIII B Zhang, M Spreafico, C Zheng, A Yang, P Platzer, MU Callaghan, Z Avci, ... Blood, The Journal of the American Society of Hematology 111 (12), 5592-5600, 2008 | 91 | 2008 |
Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment AB Nagaraj, QQ Wang, P Joseph, C Zheng, Y Chen, O Kovalenko, ... Oncogene 37 (3), 403-414, 2018 | 87 | 2018 |
Combined deficiency of coagulation factors V and VIII: an update C Zheng, B Zhang Seminars in thrombosis and hemostasis 39 (06), 613-620, 2013 | 87 | 2013 |
Heat shock protein 27 downregulates the transferrin receptor 1-mediated iron uptake H Chen, C Zheng, Y Zhang, YZ Chang, ZM Qian, X Shen The international journal of biochemistry & cell biology 38 (8), 1402-1416, 2006 | 87 | 2006 |
Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII C Zheng, H Liu, S Yuan, J Zhou, B Zhang Blood, The Journal of the American Society of Hematology 116 (25), 5698-5706, 2010 | 80 | 2010 |
The intracellular cargo receptor ERGIC-53 is required for the production of infectious arenavirus, coronavirus, and filovirus particles JP Klaus, P Eisenhauer, J Russo, AB Mason, D Do, B King, D Taatjes, ... Cell host & microbe 14 (5), 522-534, 2013 | 78 | 2013 |
Psoriasis and psoriatic arthritis cardiovascular disease endotypes identified by red blood cell distribution width and mean platelet volume RRZ Conic, G Damiani, KP Schrom, AE Ramser, C Zheng, R Xu, ... Journal of clinical medicine 9 (1), 186, 2020 | 69 | 2020 |
Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin B Zhang, C Zheng, M Zhu, J Tao, MP Vasievich, A Baines, J Kim, ... Blood, The Journal of the American Society of Hematology 118 (12), 3384-3391, 2011 | 66 | 2011 |
Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII) C Zheng, RC Page, V Das, JC Nix, E Wigren, S Misra, B Zhang Journal of Biological Chemistry 288 (28), 20499-20509, 2013 | 59 | 2013 |
Predicting cancer origins with a DNA methylation-based deep neural network model C Zheng, R Xu PloS one 15 (5), e0226461, 2020 | 56 | 2020 |
The COVID-19 hospitalization metric in the pre-and postvaccination eras as a measure of pandemic severity: A retrospective, nationwide cohort study NR Fillmore, J La, C Zheng, S Doron, NV Do, PA Monach, ... Infection Control & Hospital Epidemiology 43 (12), 1767-1772, 2022 | 47 | 2022 |
EF-hand domains of MCFD2 mediate interactions with both LMAN1 and coagulation factor V or VIII C Zheng, H Liu, J Zhou, B Zhang Blood, The Journal of the American Society of Hematology 115 (5), 1081-1087, 2010 | 39 | 2010 |
Combining phenome-driven drug-target interaction prediction with patients’ electronic health records-based clinical corroboration toward drug discovery M Zhou, C Zheng, R Xu Bioinformatics 36 (Supplement_1), i436-i444, 2020 | 33 | 2020 |
Association of epigenetic clock with consensus molecular subtypes and overall survival of colorectal cancer C Zheng, L Li, R Xu Cancer Epidemiology, Biomarkers & Prevention 28 (10), 1720-1724, 2019 | 33 | 2019 |
The neutrophil to lymphocyte ratio is associated with the risk of subsequent dementia in the Framingham Heart Study J Ramos-Cejudo, AD Johnson, A Beiser, S Seshadri, J Salinas, JS Berger, ... Frontiers in Aging Neuroscience 13, 773984, 2021 | 27 | 2021 |
Drug repurposing for opioid use disorders: integration of computational prediction, clinical corroboration, and mechanism of action analyses M Zhou, QQ Wang, C Zheng, A John Rush, ND Volkow, R Xu Molecular psychiatry 26 (9), 5286-5296, 2021 | 27 | 2021 |
Large-scale mining disease comorbidity relationships from post-market drug adverse events surveillance data C Zheng, R Xu BMC bioinformatics 19, 85-93, 2018 | 26 | 2018 |
Molecular subtyping of Alzheimer’s disease with consensus non-negative matrix factorization C Zheng, R Xu Plos one 16 (5), e0250278, 2021 | 24 | 2021 |