Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice P Sonveaux, F Végran, T Schroeder, MC Wergin, J Verrax, ZN Rabbani, ... The Journal of clinical investigation 118 (12), 3930-3942, 2008 | 1973 | 2008 |
Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis F Végran, R Boidot, C Michiels, P Sonveaux, O Feron Cancer research 71 (7), 2550-2560, 2011 | 856 | 2011 |
A mitochondrial switch promotes tumor metastasis PE Porporato, VL Payen, J Pérez-Escuredo, CJ De Saedeleer, P Danhier, ... Cell reports 8 (3), 754-766, 2014 | 624 | 2014 |
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis P Sonveaux, T Copetti, CJ De Saedeleer, F Vegran, J Verrax, ... PloS one 7 (3), e33418, 2012 | 589 | 2012 |
Regulation of HIF-1α stability through S-nitrosylation F Li, P Sonveaux, ZN Rabbani, S Liu, B Yan, Q Huang, Z Vujaskovic, ... Molecular cell 26 (1), 63-74, 2007 | 545 | 2007 |
Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review PE Porporato, S Dhup, RK Dadhich, T Copetti, P Sonveaux Frontiers in pharmacology 2, 49, 2011 | 532 | 2011 |
Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis S Dhup, R Kumar Dadhich, P Ettore Porporato, P Sonveaux Current pharmaceutical design 18 (10), 1319-1330, 2012 | 509 | 2012 |
Monocarboxylate transporters in cancer VL Payen, E Mina, VF Van Hée, PE Porporato, P Sonveaux Molecular metabolism 33, 48-66, 2020 | 476 | 2020 |
Monocarboxylate transporters in the brain and in cancer J Pérez-Escuredo, VF Van Hée, M Sboarina, J Falces, VL Payen, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (10), 2481-2497, 2016 | 422 | 2016 |
Hsp90 and caveolin are key targets for the proangiogenic nitric oxide–mediated effects of statins A Brouet, P Sonveaux, C Dessy, S Moniotte, JL Balligand, O Feron Circulation research 89 (10), 866-873, 2001 | 358 | 2001 |
Gut microbiota-derived propionate reduces cancer cell proliferation in the liver LB Bindels, P Porporato, EM Dewulf, J Verrax, AM Neyrinck, JC Martin, ... British journal of cancer 107 (8), 1337-1344, 2012 | 328 | 2012 |
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells CJ De Saedeleer, T Copetti, PE Porporato, J Verrax, O Feron, ... Public Library of Science 7 (10), e46571, 2012 | 291 | 2012 |
Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors R Boidot, F Végran, A Meulle, A Le Breton, C Dessy, P Sonveaux, ... Cancer research 72 (4), 939-948, 2012 | 283 | 2012 |
PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing KK Chereddy, CH Her, M Comune, C Moia, A Lopes, PE Porporato, ... Journal of Controlled Release 194, 138-147, 2014 | 279 | 2014 |
Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial … A Brouet, P Sonveaux, C Dessy, JL Balligand, O Feron Journal of Biological Chemistry 276 (35), 32663-32669, 2001 | 274 | 2001 |
Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice PE Porporato, VL Payen, CJ De Saedeleer, V Préat, JP Thissen, O Feron, ... Angiogenesis 15, 581-592, 2012 | 273 | 2012 |
Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implications for tumor radiotherapy P Sonveaux, A Brouet, X Havaux, V Grégoire, C Dessy, JL Balligand, ... Cancer Research 63 (5), 1012-1019, 2003 | 255 | 2003 |
Pathological effects of ionizing radiation: endothelial activation and dysfunction B Baselet, P Sonveaux, S Baatout, A Aerts Cellular and molecular life sciences 76, 699-728, 2019 | 254 | 2019 |
Caveolin-1 expression is critical for vascular endothelial growth factor–induced ischemic hindlimb collateralization and nitric oxide–mediated angiogenesis P Sonveaux, P Martinive, J DeWever, Z Batova, G Daneau, M Pelat, ... Circulation research 95 (2), 154-161, 2004 | 242 | 2004 |
Cancer metabolism in space and time: beyond the Warburg effect P Danhier, P Bański, VL Payen, D Grasso, L Ippolito, P Sonveaux, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1858 (8), 556-572, 2017 | 236 | 2017 |