Efficient generation of lung and airway epithelial cells from human pluripotent stem cells SXL Huang, MN Islam, J O'neill, Z Hu, YG Yang, YW Chen, M Mumau, ... Nature biotechnology 32 (1), 84, 2014 | 620 | 2014 |
A three-dimensional model of human lung development and disease from pluripotent stem cells YW Chen, SX Huang, ALRT De Carvalho, SH Ho, MN Islam, S Volpi, ... Nature cell biology 19 (5), 542-549, 2017 | 574 | 2017 |
Handbook of proteolytic enzymes ND Rawlings, G Salvesen Academic press 135, 141, 2013 | 521* | 2013 |
TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate … YW Chen, MS Lee, A Lucht, FP Chou, W Huang, TC Havighurst, KM Kim, ... The American journal of pathology 176 (6), 2986-2996, 2010 | 226 | 2010 |
Modeling of fibrotic lung disease using 3D organoids derived from human pluripotent stem cells A Strikoudis, A Cieślak, L Loffredo, YW Chen, N Patel, A Saqi, DJ Lederer, ... Cell reports 27 (12), 3709-3723. e5, 2019 | 216 | 2019 |
The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells SXL Huang, MD Green, AT De Carvalho, M Mumau, YW Chen, ... Nature protocols 10 (3), 413, 2015 | 216 | 2015 |
Authentic Modeling of human respiratory virus infection in human pluripotent stem cell-derived lung Organoids M Porotto, M Ferren, YW Chen, Y Siu, N Makhsous, B Rima, T Briese, ... MBio 10 (3), e00723-19, 2019 | 135 | 2019 |
Analgesic and antiinflammatory activities of the aqueous extract from Plectranthus amboinicus (Lour.) Spreng. both in vitro and in vivo YJ Chiu, TH Huang, CS Chiu, TC Lu, YW Chen, WH Peng, CY Chen Evidence-Based Complementary and Alternative Medicine 2012, 2012 | 130 | 2012 |
MicroRNA and ROS crosstalk in cardiac and pulmonary diseases M Climent, G Viggiani, YW Chen, G Coulis, A Castaldi International Journal of Molecular Sciences 21 (12), 4370, 2020 | 118 | 2020 |
The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics A Thakur, X Ke, YW Chen, P Motallebnejad, K Zhang, Q Lian, HJ Chen Protein & Cell, 1-24, 2021 | 93 | 2021 |
3D modeling of esophageal development using human PSC-derived basal progenitors reveals a critical role for notch signaling Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, ... Cell stem cell 23 (4), 516-529. e5, 2018 | 89 | 2018 |
Functional vascularized lung grafts for lung bioengineering NV Dorrello, BA Guenthart, JD O’Neill, J Kim, K Cunningham, YW Chen, ... Science advances 3 (8), e1700521, 2017 | 89 | 2017 |
Zymogen activation, inhibition, and ectodomain shedding of matriptase. CY Lin, IC Tseng, FP Chou, SF Su, YW Chen, MD Johnson, RB Dickson Frontiers in bioscience: a journal and virtual library 13, 621-635, 2008 | 85 | 2008 |
Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition JK Wang, MS Lee, IC Tseng, FP Chou, YW Chen, A Fulton, HS Lee, ... American Journal of Physiology-Cell Physiology 297 (2), C459-C470, 2009 | 78 | 2009 |
Regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation YW Chen, JK Wang, FP Chou, CY Chen, EA Rorke, LM Chen, KX Chai, ... Journal of Biological Chemistry 285 (41), 31755-31762, 2010 | 76 | 2010 |
Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs AE Hozain, JD O’Neill, MR Pinezich, Y Tipograf, R Donocoff, ... Nature Medicine 26 (7), 1102-1113, 2020 | 71 | 2020 |
Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model Q Lian, K Zhang, Z Zhang, F Duan, L Guo, W Luo, BWY Mok, A Thakur, ... Nature communications 13 (1), 2028, 2022 | 65 | 2022 |
Cross-circulation for extracorporeal support and recovery of the lung JD O’Neill, BA Guenthart, J Kim, S Chicotka, D Queen, K Fung, C Marboe, ... Nature Biomedical Engineering 1 (3), 1-15, 2017 | 58 | 2017 |
Glycogen synthase kinase 3 induces multilineage maturation of human pluripotent stem cell-derived lung progenitors in 3D culture ALRT de Carvalho, A Strikoudis, HY Liu, YW Chen, TJ Dantas, RB Vallee, ... Development 146 (2), dev171652, 2019 | 54 | 2019 |
Modeling COVID-19 with human pluripotent stem cell-derived cells reveals synergistic effects of anti-inflammatory macrophages with ACE2 inhibition against SARS-CoV-2 F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Payant, P Wang, ... Research square, 2020 | 48 | 2020 |