Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome AJ Cohen, A Saiakhova, O Corradin, JM Luppino, K Lovrenert, CF Bartels, ... Nature communications 8 (1), 14400, 2017 | 122 | 2017 |
Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes JM Luppino, DS Park, SC Nguyen, Y Lan, Z Xu, R Yunker, EF Joyce Nature genetics 52 (8), 840-848, 2020 | 114 | 2020 |
Modeling disease risk through analysis of physical interactions between genetic variants within chromatin regulatory circuitry O Corradin, AJ Cohen, JM Luppino, IM Bayles, FR Schumacher, ... Nature genetics 48 (11), 1313-1320, 2016 | 67 | 2016 |
BRD4 orchestrates genome folding to promote neural crest differentiation R Linares-Saldana, W Kim, NA Bolar, H Zhang, BA Koch-Bojalad, S Yoon, ... Nature genetics 53 (10), 1480-1492, 2021 | 64 | 2021 |
ARID1A spatially partitions interphase chromosomes S Wu, N Fatkhutdinov, L Rosin, JM Luppino, O Iwasaki, H Tanizawa, ... Science advances 5 (5), eaaw5294, 2019 | 39 | 2019 |
Multi-feature clustering of CTCF binding creates robustness for loop extrusion blocking and Topologically Associating Domain boundaries LH Chang, S Ghosh, A Papale, JM Luppino, M Miranda, V Piras, ... Nature Communications 14 (1), 5615, 2023 | 26 | 2023 |
High-throughput Oligopaint screen identifies druggable 3D genome regulators DS Park, SC Nguyen, R Isenhart, PP Shah, W Kim, RJ Barnett, A Chandra, ... Nature 620 (7972), 209-217, 2023 | 23 | 2023 |
Single cell analysis pushes the boundaries of TAD formation and function JM Luppino, EF Joyce Current opinion in genetics & development 61, 25-31, 2020 | 21 | 2020 |
CTCF blocks antisense transcription initiation at divergent promoters J Luan, MW Vermunt, CM Syrett, A Coté, JM Tome, H Zhang, A Huang, ... Nature structural & molecular biology 29 (11), 1136-1144, 2022 | 20 | 2022 |
Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome T Malachowski, KR Chandradoss, R Boya, L Zhou, AL Cook, C Su, ... Cell 186 (26), 5840-5858. e36, 2023 | 12 | 2023 |
Co-depletion of NIPBL and WAPL balance cohesin activity to correct gene misexpression JM Luppino, A Field, SC Nguyen, DS Park, PP Shah, RJ Abdill, Y Lan, ... PLoS genetics 18 (11), e1010528, 2022 | 11 | 2022 |
CTCF blocks anti-sense transcription initiation at divergent gene promoters J Luan, CM Syrett, MW Vermunt, A Coté, JM Tome, H Zhang, A Huang, ... BioRxiv, 2021.10. 30.465508, 2021 | 7 | 2021 |
NIPBL and WAPL balance cohesin activity to regulate chromatin folding and gene expression JM Luppino, A Field, SC Nguyen, DS Park, PP Shah, Y Lan, R Yunker, ... bioRxiv, 2022.04. 19.488785, 2022 | 5 | 2022 |
High-throughput Oligopaint screen identifies druggable regulators of genome folding DS Park, SC Nguyen, R Isenhart, PP Shah, W Kim, RJ Barnett, A Chandra, ... bioRxiv, 2022.04. 08.487672, 2022 | 5 | 2022 |
Investigating The Role Of Cohesin In Dynamic Genome Folding And Gene Regulation JM Luppino University of Pennsylvania, 2022 | | 2022 |
Publisher Correction: BRD4 orchestrates genome folding to promote neural crest differentiation R Linares-Saldana, W Kim, NA Bolar, H Zhang, BA Koch-Bojalad, S Yoon, ... Nature Genetics 53 (12), 1723-1723, 2021 | | 2021 |
Genome-wide association study in asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus V Kumar, HJ Westra, J Karjalainen, DV Zhernakova, T Esko, B Hrdlickova, ... Nature, 2016 | | 2016 |
ARID1A spatially partitions interphase chromosomes O Iwasaki, J Luppino, A Kossenkov, R Zhang, S Wu, E Joyce, H Tang, ... | | |