| Modulators of protein–protein interactions LG Milroy, TN Grossmann, S Hennig, L Brunsveld, C Ottmann Chemical reviews 114 (9), 4695-4748, 2014 | 535 | 2014 |
| Structural view of a fungal toxin acting on a 14‐3‐3 regulatory complex M Würtele, C Jelich‐Ottmann, A Wittinghofer, C Oecking The EMBO journal, 2003 | 397 | 2003 |
| Phosphorylation of Thr-948 at the C Terminus of the Plasma Membrane H+-ATPase Creates a Binding Site for the Regulatory 14-3-3 Protein F Svennelid, A Olsson, M Piotrowski, M Rosenquist, C Ottman, C Larsson, ... The Plant Cell 11 (12), 2379-2391, 1999 | 302 | 1999 |
| A common toxin fold mediates microbial attack and plant defense C Ottmann, B Luberacki, I Küfner, W Koch, F Brunner, M Weyand, ... Proceedings of the National Academy of Sciences 106 (25), 10359-10364, 2009 | 287 | 2009 |
| Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+-ATPase by combining X-ray crystallography and electron cryomicroscopy C Ottmann, S Marco, N Jaspert, C Marcon, N Schauer, M Weyand, ... Molecular cell 25 (3), 427-440, 2007 | 285 | 2007 |
| Modulators of 14-3-3 protein–protein interactions LM Stevers, E Sijbesma, M Botta, C MacKintosh, T Obsil, I Landrieu, ... Journal of medicinal chemistry 61 (9), 3755-3778, 2017 | 277 | 2017 |
| Small‐Molecule Stabilization of Protein–Protein Interactions: An Underestimated Concept in Drug Discovery? P Thiel, M Kaiser, C Ottmann Angewandte Chemie International Edition 51 (9), 2012-2018, 2012 | 243 | 2012 |
| Supramolecular chemistry targeting proteins S van Dun, C Ottmann, LG Milroy, L Brunsveld Journal of the American Chemical Society 139 (40), 13960-13968, 2017 | 206 | 2017 |
| Molecular tweezers modulate 14-3-3 protein–protein interactions D Bier, R Rose, K Bravo-Rodriguez, M Bartel, JM Ramirez-Anguita, S Dutt, ... Nature chemistry 5 (3), 234-239, 2013 | 204 | 2013 |
| Phosphorylation‐independent interaction between 14‐3‐3 and exoenzyme S: from structure to pathogenesis C Ottmann, L Yasmin, M Weyand, JL Veesenmeyer, MH Diaz, RH Palmer, ... The EMBO journal 26 (3), 902-913, 2007 | 203 | 2007 |
| Stabilization of protein-protein interactions in drug discovery SA Andrei, E Sijbesma, M Hann, J Davis, G O’Mahony, MWD Perry, ... Expert opinion on drug discovery 12 (9), 925-940, 2017 | 172 | 2017 |
| Constrained peptides with target‐adapted cross‐links as inhibitors of a pathogenic protein–protein interaction A Glas, D Bier, G Hahne, C Rademacher, C Ottmann, TN Grossmann Angewandte Chemie International Edition 53 (9), 2489-2493, 2014 | 165 | 2014 |
| Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling M Molzan, B Schumacher, C Ottmann, A Baljuls, L Polzien, M Weyand, ... Molecular and cellular biology 30 (19), 4698-4711, 2010 | 152 | 2010 |
| Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface IJ De Vries-van Leeuwen, D da Costa Pereira, KD Flach, SR Piersma, ... Proceedings of the National Academy of Sciences 110 (22), 8894-8899, 2013 | 149 | 2013 |
| Intermolecular channels direct crystal orientation in mineralized collagen YF Xu, F Nudelman, ED Eren, MJM Wirix, B Cantaert, WH Nijhuis, ... Nature communications 11 (1), 5068, 2020 | 138 | 2020 |
| Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR LM Stevers, CV Lam, SFR Leysen, FA Meijer, DS van Scheppingen, ... Proceedings of the National Academy of Sciences 113 (9), E1152-E1161, 2016 | 137 | 2016 |
| Identification and Structure of Small‐Molecule Stabilizers of 14–3–3 Protein–Protein Interactions R Rose, S Erdmann, S Bovens, A Wolf, M Rose, S Hennig, H Waldmann, ... Angewandte Chemie International Edition 49 (24), 4129-4132, 2010 | 136 | 2010 |
| Ultra-large chemical libraries for the discovery of high-affinity peptide binders AJ Quartararo, ZP Gates, BA Somsen, N Hartrampf, X Ye, A Shimada, ... Nature communications 11 (1), 3183, 2020 | 116 | 2020 |
| Stabilization of physical RAF/14-3-3 interaction by cotylenin A as treatment strategy for RAS mutant cancers M Molzan, S Kasper, L Röglin, M Skwarczynska, T Sassa, T Inoue, ... ACS chemical biology 8 (9), 1869-1875, 2013 | 115 | 2013 |
| High-throughput screening to identify inhibitors which stabilize inactive kinase conformations in p38α JR Simard, V Pawar, B Aust, A Wolf, M Rabiller, S Wulfert, A Robubi, ... Journal of the American Chemical Society 131 (51), 18478-18488, 2009 | 113 | 2009 |
Michael WeyandSenior Staff Scientist, University of Bayreuth確認したメール アドレス: uni-bayreuth.de