Insights into the kinetics of Ca2+-regulated contraction and relaxation from myofibril studies R Stehle, J Solzin, B Iorga, C Poggesi Pflügers Archiv-European Journal of Physiology 458, 337-357, 2009 | 100 | 2009 |
Kinetics of cardiac sarcomeric processes and rate-limiting steps in contraction and relaxation R Stehle, B Iorga Journal of molecular and cellular cardiology 48 (5), 843-850, 2010 | 86 | 2010 |
Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes N Weber, K Schwanke, S Greten, M Wendland, B Iorga, M Fischer, ... Basic research in cardiology 111, 1-16, 2016 | 60 | 2016 |
The slow skeletal muscle isoform of myosin shows kinetic features common to smooth and non-muscle myosins B Iorga, N Adamek, MA Geeves Journal of Biological Chemistry 282 (6), 3559-3570, 2007 | 57 | 2007 |
Differences in contractile function of myofibrils within human embryonic stem cell-derived cardiomyocytes vs. adult ventricular myofibrils are related to distinct sarcomeric … B Iorga, K Schwanke, N Weber, M Wendland, S Greten, B Piep, ... Frontiers in Physiology 8, 1111, 2018 | 50 | 2018 |
Lys184 deletion in troponin I impairs relaxation kinetics and induces hypercontractility in murine cardiac myofibrils B Iorga, N Blaudeck, J Solzin, A Neulen, I Stehle, AJL Davila, G Pfitzer, ... Cardiovascular research 77 (4), 676-686, 2008 | 40 | 2008 |
Kinetic mechanism of the Ca2+-dependent switch-on and switch-off of cardiac troponin in myofibrils J Solzin, B Iorga, E Sierakowski, DPG Alcazar, DF Ruess, T Kubacki, ... Biophysical journal 93 (11), 3917-3931, 2007 | 36 | 2007 |
Why choose myofibrils to study muscle myosin ATPase? C Lionne, B Iorga, R Candau, F Travers Journal of Muscle Research & Cell Motility 24, 139-148, 2003 | 34 | 2003 |
At physiological temperatures the ATPase rates of shortening soleus and psoas myofibrils are similar R Candau, B Iorga, F Travers, T Barman, C Lionne Biophysical journal 85 (5), 3132-3141, 2003 | 33 | 2003 |
Evidence that phosphate release is the rate-limiting step on the overall ATPase of psoas myofibrils prevented from shortening by chemical cross-linking C Lionne, B Iorga, R Candau, N Piroddi, MR Webb, A Belus, F Travers, ... Biochemistry 41 (44), 13297-13308, 2002 | 32 | 2002 |
Mechanical properties of sarcomeres during cardiac myofibrillar relaxation: stretch-induced cross-bridge detachment contributes to early diastolic filling R Stehle, J Solzin, B Iorga, D Gomez, N Blaudeck, G Pfitzer Journal of Muscle Research & Cell Motility 27, 423-434, 2006 | 29 | 2006 |
Micromechanical function of myofibrils isolated from skeletal and cardiac muscles of the zebrafish B Iorga, CD Neacsu, WF Neiss, R Wagener, M Paulsson, R Stehle, ... Journal of General Physiology 137 (3), 255-270, 2011 | 25 | 2011 |
mTOR inhibition via displacement of phosphatidic acid induces enhanced cytotoxicity specifically in cancer cells TL Nguyen, MJ Nokin, M Egorov, M Tomé, C Bodineau, C Di Primo, ... Cancer Research 78 (18), 5384-5397, 2018 | 23 | 2018 |
A thermophoresis–based biosensor for real–time detection of inorganic phosphate during enzymatic reactions P Franz, V Gassl, A Topf, L Eckelmann, B Iorga, G Tsiavaliaris Biosensors and Bioelectronics 169, 112616, 2020 | 19 | 2020 |
ATP binding and cross‐bridge detachment steps during full Ca2+ activation: comparison of myofibril and muscle fibre mechanics by sinusoidal analysis B Iorga, L Wang, R Stehle, G Pfitzer, M Kawai The Journal of physiology 590 (14), 3361-3373, 2012 | 15 | 2012 |
Paradoxical effects of endurance training and chronic hypoxia on myofibrillar ATPase activity B Roels, C Reggiani, C Reboul, C Lionne, B Iorga, P Obert, S Tanguy, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008 | 15 | 2008 |
Calcium regulation of troponin and its role in the dynamics of contraction and relaxation R Stehle, B Iorga, G Pfitzer American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007 | 15 | 2007 |
Postnatal development of right ventricular myofibrillar biomechanics in relation to the sarcomeric protein phenotype in pediatric patients with conotruncal heart defects F Elhamine, B Iorga, M Krüger, M Hunger, J Eckhardt, N Sreeram, ... Journal of the American Heart Association 5 (6), e003699, 2016 | 10 | 2016 |
Phosphate has dual roles in cross-bridge kinetics in rabbit psoas single myofibrils M Kawai, R Stehle, G Pfitzer, B Iorga Journal of General Physiology 153 (3), e202012755, 2021 | 8 | 2021 |
Does phosphate release limit the ATPases of soleus myofibrils? Evidence that (A)M· ADP·Pi states predominate on the cross-bridge cycle B Iorga, R Candau, F Travers, T Barman, C Lionne Journal of Muscle Research & Cell Motility 25, 367-378, 2004 | 8 | 2004 |