Regulation of Nrf2 by mitochondrial reactive oxygen species in physiology and pathology S Kasai, S Shimizu, Y Tatara, J Mimura, K Itoh Biomolecules 10 (2), 320, 2020 | 409 | 2020 |
Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control S Kasai, H Yamazaki, K Tanji, MJ Engler, T Matsumiya, K Itoh Journal of clinical biochemistry and nutrition 64 (1), 1-12, 2019 | 94 | 2019 |
Emerging regulatory role of Nrf2 in iron, heme, and hemoglobin metabolism in physiology and disease S Kasai, J Mimura, T Ozaki, K Itoh Frontiers in veterinary science 5, 242, 2018 | 63 | 2018 |
A somatic mutation of the KEAP1 gene in malignant melanoma is involved in aberrant NRF2 activation and an increase in intrinsic drug resistance S Miura, M Shibazaki, S Kasai, S Yasuhira, A Watanabe, T Inoue, ... The Journal of investigative dermatology 134 (2), 553-556, 2014 | 42 | 2014 |
Calcium/calmodulin signaling elicits release of cytochrome c during 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced apoptosis in the human lymphoblastic T-cell line, L-MAT D Kobayashi, S Ahmed, M Ishida, S Kasai, H Kikuchi Toxicology 258 (1), 25-32, 2009 | 39 | 2009 |
BCL 2 and BCL xL are key determinants of resistance to antitubulin chemotherapeutics in melanoma cells A Watanabe, S Yasuhira, T Inoue, S Kasai, M Shibazaki, K Takahashi, ... Experimental Dermatology 22 (8), 518-523, 2013 | 38 | 2013 |
Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice H Yamazaki, S Kasai, J Mimura, P Ye, A Inose-Maruyama, K Tanji, ... PLoS genetics 16 (4), e1008693, 2020 | 37 | 2020 |
Concomitant Nrf2-and ATF4-activation by carnosic acid cooperatively induces expression of cytoprotective genes J Mimura, A Inose-Maruyama, S Taniuchi, K Kosaka, H Yoshida, ... International Journal of Molecular Sciences 20 (7), 1706, 2019 | 32 | 2019 |
Transcriptional and post-transcriptional regulation of βIII-tubulin protein expression in relation with cell cycle-dependent regulation of tumor cells M Shibazaki, C Maesawa, K Akasaka, S Kasai, S Yasuhira, K Kanno, ... International journal of oncology 40 (3), 695-702, 2012 | 30 | 2012 |
Immunohistochemistry for histone h3 lysine 9 methyltransferase and demethylase proteins in human melanomas S Miura, C Maesawa, M Shibazaki, S Yasuhira, S Kasai, K Tsunoda, ... The American Journal of Dermatopathology 36 (3), 211-216, 2014 | 28 | 2014 |
Bcl‑2/Bcl‑xL inhibitor ABT‑737 sensitizes pancreatic ductal adenocarcinoma to paclitaxel‑induced cell death S Kasai, T Sasaki, A Watanabe, M Nishiya, S Yasuhira, M Shibazaki, ... Oncology letters 14 (1), 903-908, 2017 | 24 | 2017 |
The inhibitory mechanisms of the tyrosine kinase inhibitors herbimycin a, genistein, and tyrphostin B48 with regard to the function of the aryl hydrocarbon receptor in Caco-2 cells S Kasai, H Kikuchi Bioscience, biotechnology, and biochemistry 74 (1), 36-43, 2010 | 23 | 2010 |
Dephosphorylation of Sp1 at Ser-59 by protein phosphatase 2A (PP2A) is required for induction of CYP1A1 transcription after treatment with 2, 3, 7, 8-tetrachlorodibenzo-p … S Shimoyama, S Kasai, B Kahn-Perlès, H Kikuchi Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (2), 107-115, 2014 | 21 | 2014 |
NAD (P) H: Quinone oxidoreductase-1 expression sensitizes malignant melanoma cells to the HSP90 inhibitor 17-AAG S Kasai, N Arakawa, A Okubo, W Shigeeda, S Yasuhira, T Masuda, ... PloS one 11 (4), e0153181, 2016 | 19 | 2016 |
Sulforaphane increase mitochondrial biogenesis-related gene expression in the hippocampus and suppresses age-related cognitive decline in mice S Shimizu, S Kasai, H Yamazaki, Y Tatara, J Mimura, MJ Engler, K Tanji, ... International Journal of Molecular Sciences 23 (15), 8433, 2022 | 17 | 2022 |
β-Catenin signaling induces CYP1A1 expression by disrupting adherens junctions in Caco-2 human colon carcinoma cells S Kasai, T Ishigaki, R Takumi, T Kamimura, H Kikuchi Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (3), 2509-2516, 2013 | 17 | 2013 |
Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging S Shimizu, J Mimura, T Hasegawa, E Shimizu, S Imoto, M Tsushima, ... PLoS One 15 (8), e0236834, 2020 | 16 | 2020 |
Mitochondrial reactive oxygen species, insulin resistance, and Nrf2-mediated oxidative stress response—Toward an actionable strategy for anti-aging S Kasai, D Kokubu, H Mizukami, K Itoh Biomolecules 13 (10), 1544, 2023 | 13 | 2023 |
Prevalence of the mitochondrial 1555 A> G and 1494 C> T mutations in a community-dwelling population in Japan Y Maeda, A Sasaki, S Kasai, S Goto, S Nishio, K Sawada, I Tokuda, K Itoh, ... Human genome variation 7 (1), 27, 2020 | 13 | 2020 |
Mitochondrial E3 ubiquitin ligase parkin: relationships with other causal proteins in familial Parkinson’s disease and its substrate-involved mouse experimental models S Torii, S Kasai, T Yoshida, K Yasumoto, S Shimizu International Journal of Molecular Sciences 21 (4), 1202, 2020 | 12 | 2020 |