Hypoxic pulmonary vasoconstriction: from molecular mechanisms to medicine KJ Dunham-Snary, D Wu, EA Sykes, A Thakrar, LRG Parlow, JD Mewburn, ... Chest 151 (1), 181-192, 2017 | 501 | 2017 |
Mitochondrial iron–sulfur clusters: Structure, function, and an emerging role in vascular biology AD Read, RET Bentley, SL Archer, KJ Dunham-Snary Redox Biology 47, 102164, 2021 | 213 | 2021 |
MicroRNA-138 and microRNA-25 down-regulate mitochondrial calcium uniporter, causing the pulmonary arterial hypertension cancer phenotype Z Hong, KH Chen, A DasGupta, F Potus, K Dunham-Snary, S Bonnet, ... American journal of respiratory and critical care medicine 195 (4), 515-529, 2017 | 146 | 2017 |
Epigenetic dysregulation of the dynamin-related protein 1 binding partners MiD49 and MiD51 increases mitotic mitochondrial fission and promotes pulmonary arterial hypertension … KH Chen, A Dasgupta, J Lin, F Potus, S Bonnet, J Iremonger, J Fu, ... Circulation 138 (3), 287-304, 2018 | 145 | 2018 |
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension L Tian, M Neuber-Hess, J Mewburn, A Dasgupta, K Dunham-Snary, D Wu, ... Journal of molecular medicine 95, 381-393, 2017 | 111 | 2017 |
Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload JL Fetterman, BR Zelickson, LW Johnson, DR Moellering, DG Westbrook, ... Biochemical Journal 455 (2), 157-167, 2013 | 104 | 2013 |
Ndufs2, a core subunit of mitochondrial complex I, is essential for acute oxygen-sensing and hypoxic pulmonary vasoconstriction KJ Dunham-Snary, D Wu, F Potus, EA Sykes, JD Mewburn, RL Charles, ... Circulation research 124 (12), 1727-1746, 2019 | 93 | 2019 |
The mitochondrial paradigm for cardiovascular disease susceptibility and cellular function: a complementary concept to Mendelian genetics DM Krzywanski, DR Moellering, JL Fetterman, KJ Dunham-Snary, ... Laboratory investigation 91 (8), 1122-1135, 2011 | 67 | 2011 |
Mitochondria in the pulmonary vasculature in health and disease: oxygen-sensing, metabolism, and dynamics A Dasgupta, D Wu, L Tian, PY Xiong, KJ Dunham-Snary, KH Chen, ... Comprehensive Physiology 10 (2), 713-765, 2020 | 55 | 2020 |
Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling AL Theilmann, LG Hawke, LR Hilton, MKM Whitford, DV Cole, JL Mackeil, ... Arteriosclerosis, thrombosis, and vascular biology 40 (11), 2605-2618, 2020 | 52 | 2020 |
Mitochondrial–nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivo KJ Dunham-Snary, MW Sandel, MJ Sammy, DG Westbrook, R Xiao, ... EBioMedicine 36, 316-328, 2018 | 52 | 2018 |
Mitochondria in human neutrophils mediate killing of Staphylococcus aureus KJ Dunham-Snary, BGJ Surewaard, JD Mewburn, RET Bentley, AY Martin, ... Redox biology 49, 102225, 2022 | 50 | 2022 |
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer D Wu, A Dasgupta, AD Read, RET Bentley, M Motamed, KH Chen, ... Free Radical Biology and Medicine 170, 150-178, 2021 | 50 | 2021 |
Transcriptomic signature of right ventricular failure in experimental pulmonary arterial hypertension: deep sequencing demonstrates mitochondrial, fibrotic, inflammatory and … F Potus, CCT Hindmarch, KJ Dunham-Snary, J Stafford, SL Archer International journal of molecular sciences 19 (9), 2730, 2018 | 50 | 2018 |
The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease AL King, SK Mantena, KK Andringa, T Millender-Swain, ... Redox biology 9, 188-197, 2016 | 49 | 2016 |
Mitochondrial-nuclear DNA mismatch matters KJ Dunham-Snary, SW Ballinger Science 349 (6255), 1449-1450, 2015 | 44 | 2015 |
Mitochondrial genetics and obesity: evolutionary adaptation and contemporary disease susceptibility KJ Dunham-Snary, SW Ballinger Free Radical Biology and Medicine 65, 1229-1237, 2013 | 44 | 2013 |
A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus KJ Dunham-Snary, ZG Hong, PY Xiong, JC Del Paggio, JE Herr, AM Johri, ... Pflügers Archiv-European Journal of Physiology 468, 43-58, 2016 | 43 | 2016 |
A method for assessing mitochondrial bioenergetics in whole white adipose tissues KJ Dunham-Snary, MW Sandel, DG Westbrook, SW Ballinger Redox biology 2, 656-660, 2014 | 41 | 2014 |
SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia SL Archer, A Dasgupta, KH Chen, D Wu, K Baid, JE Mamatis, V Gonzalez, ... Redox biology 58, 102508, 2022 | 35 | 2022 |