フォロー
Benjamin J. Orlando
Benjamin J. Orlando
Assistant Professor, Michigan State University
確認したメール アドレス: msu.edu
タイトル
引用先
引用先
Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex
M Fan, J Zhang, CW Tsai, BJ Orlando, M Rodriguez, Y Xu, M Liao, ...
Nature 582 (7810), 129-133, 2020
2312020
Crystal structure of aspirin-acetylated human cyclooxygenase-2: insight into the formation of products with reversed stereochemistry
MJ Lucido, BJ Orlando, AJ Vecchio, MG Malkowski
Biochemistry 55 (8), 1226-1238, 2016
2232016
Substrate-selective inhibition of cyclooxygeanse-2 by fenamic acid derivatives is dependent on peroxide tone
BJ Orlando, MG Malkowski
Journal of Biological Chemistry 291 (29), 15069-15081, 2016
1962016
The structure of ibuprofen bound to cyclooxygenase-2
BJ Orlando, MJ Lucido, MG Malkowski
Journal of structural biology 189 (1), 62-66, 2015
1812015
ABCG2 transports anticancer drugs via a closed-to-open switch
BJ Orlando, M Liao
Nature communications 11 (1), 2264, 2020
1762020
Crystal structure of rofecoxib bound to human cyclooxygenase-2
BJ Orlando, MG Malkowski
Acta Crystallographica Section F: Structural Biology Communications 72 (10 …, 2016
1712016
Structural basis of lipopolysaccharide extraction by the LptB2FGC complex
Y Li, BJ Orlando, M Liao
Nature 567 (7749), 486-490, 2019
1612019
X-ray and cryo-EM structures of the mitochondrial calcium uniporter
C Fan, M Fan, BJ Orlando, NM Fastman, J Zhang, Y Xu, MG Chambers, ...
Nature 559 (7715), 575-579, 2018
1362018
Large protein organelles form a new iron sequestration system with high storage capacity
TW Giessen, BJ Orlando, AA Verdegaal, MG Chambers, J Gardener, ...
Elife 8, e46070, 2019
1342019
Structure and mechanism of the cation–chloride cotransporter NKCC1
TA Chew, BJ Orlando, J Zhang, NR Latorraca, A Wang, SA Hollingsworth, ...
Nature 572 (7770), 488-492, 2019
1222019
Investigating substrate promiscuity in cyclooxygenase-2: the role of Arg-120 and residues lining the hydrophobic groove
AJ Vecchio, BJ Orlando, R Nandagiri, MG Malkowski
Journal of Biological Chemistry 287 (29), 24619-24630, 2012
602012
Fatty acid binding to the allosteric subunit of cyclooxygenase-2 relieves a tonic inhibition of the catalytic subunit
L Dong, C Yuan, BJ Orlando, MG Malkowski, WL Smith
Journal of Biological Chemistry 291 (49), 25641-25655, 2016
362016
Cyclooxygenase-2 catalysis and inhibition in lipid bilayer nanodiscs
BJ Orlando, DR McDougle, MJ Lucido, ET Eng, LA Graham, C Schneider, ...
Archives of biochemistry and biophysics 546, 33-40, 2014
252014
Architecture of a complete Bce-type antimicrobial peptide resistance module
NL George, BJ Orlando
Nature communications 14 (1), 3896, 2023
232023
Conformational snapshots of the bacitracin sensing and resistance transporter BceAB
NL George, AL Schilmiller, BJ Orlando
Proceedings of the National Academy of Sciences 119 (14), e2123268119, 2022
192022
High-resolution views of lipopolysaccharide translocation driven by ABC transporters MsbA and LptB2FGC
F Thélot, BJ Orlando, Y Li, M Liao
Current opinion in structural biology 63, 26-33, 2020
142020
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes
BJ Orlando, PK Dominik, S Roy, CP Ogbu, SK Erramilli, AA Kossiakoff, ...
Journal of Biological Chemistry 298 (9), 2022
122022
Pulsed dipolar spectroscopy reveals that tyrosyl radicals are generated in both monomers of the cyclooxygenase-2 dimer
BJ Orlando, PP Borbat, ER Georgieva, JH Freed, MG Malkowski
Biochemistry 54 (50), 7309-7312, 2015
122015
Guarding the walls: the multifaceted roles of Bce modules in cell envelope stress sensing and antimicrobial resistance
NL George, EC Bennett, BJ Orlando
Journal of Bacteriology, e00123-24, 2024
22024
Structure and Post-Translational Modification of the Prostaglandin Transporter
P Yu, MA Orlando, BJ Orlando
bioRxiv, 2024.12. 31.630934, 2025
2025
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