| MYC deregulation in primary human cancers M Kalkat, J De Melo, KA Hickman, C Lourenco, C Redel, D Resetca, ... Genes 8 (6), 151, 2017 | 419 | 2017 |
| MYC protein interactors in gene transcription and cancer C Lourenco, D Resetca, C Redel, P Lin, AS MacDonald, R Ciaccio, ... Nature Reviews Cancer 21 (9), 579-591, 2021 | 231 | 2021 |
| MYC protein interactome profiling reveals functionally distinct regions that cooperate to drive tumorigenesis M Kalkat, D Resetca, C Lourenco, PK Chan, Y Wei, YJ Shiah, N Vitkin, ... Molecular cell 72 (5), 836-848. e7, 2018 | 206 | 2018 |
| Myc and its interactors take shape WB Tu, S Helander, R Pilstål, KA Hickman, C Lourenco, I Jurisica, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (5), 469-483, 2015 | 149 | 2015 |
| MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis WB Tu, YJ Shiah, C Lourenco, PJ Mullen, D Dingar, C Redel, A Tamachi, ... Cancer cell 34 (4), 579-595. e8, 2018 | 117 | 2018 |
| Assessment of hypoxia in the stroma of patient-derived pancreatic tumor xenografts I Lohse, C Lourenco, E Ibrahimov, M Pintilie, MS Tsao, DW Hedley Cancers 6 (1), 459-471, 2014 | 67 | 2014 |
| MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability D Dingar, WB Tu, D Resetca, C Lourenco, A Tamachi, J De Melo, ... Nature communications 9 (1), 3502, 2018 | 60 | 2018 |
| Inhibiting MYC binding to the E-box DNA motif by ME47 decreases tumour xenograft growth LC Lustig, D Dingar, WB Tu, C Lourenco, M Kalkat, I Inamoto, R Ponzielli, ... Oncogene 36 (49), 6830-6837, 2017 | 38 | 2017 |
| Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning P Mergenthaler, S Hariharan, JM Pemberton, C Lourenco, LZ Penn, ... PLoS computational biology 17 (2), e1008630, 2021 | 26 | 2021 |
| Modelling the MYC-driven normal-to-tumour switch in breast cancer C Lourenco, M Kalkat, KE Houlahan, J De Melo, J Longo, SJ Done, ... Disease models & mechanisms 12 (7), dmm038083, 2019 | 24 | 2019 |
| Lysine-52 stabilizes the MYC oncoprotein through an SCFFbxw7-independent mechanism J De Melo, SS Kim, C Lourenco, LZ Penn Oncogene 36 (49), 6815-6822, 2017 | 12 | 2017 |
| Topoisomerase 1 inhibition in MYC-driven cancer promotes aberrant R-loop accumulation to induce synthetic lethality P Lin, C Lourenco, J Cruickshank, L Palomero, JE Van Leeuwen, ... Cancer Research 83 (24), 4015-4029, 2023 | 9 | 2023 |
| Identifying MYC-dependent vulnerabilities in breast cancer C Lourenco University of Toronto (Canada), 2020 | 1 | 2020 |
| Modeling the MYC-driven normal-to-tumour switch in breast cancer C Lourenco, M Kalkat, KE Houlahan, JD Melo, J Longo, SJ Done, ... bioRxiv, 380931, 2018 | 1 | 2018 |
| Identifying MYC post-translational modiofications using a mass spectrometry-based approach D Resetca, M Kalkat, C Lourenco, PK Chan, T Srikumar, B Raught, ... MOLECULAR CANCER RESEARCH 13, 2015 | | 2015 |