Opportunities and obstacles for deep learning in biology and medicine T Ching, DS Himmelstein, BK Beaulieu-Jones, AA Kalinin, BT Do, ... Journal of the royal society interface 15 (141), 20170387, 2018 | 2295 | 2018 |
Understanding multicellular function and disease with human tissue-specific networks CS Greene, A Krishnan, AK Wong, E Ricciotti, RA Zelaya, ... Nature genetics 47 (6), 569-576, 2015 | 925 | 2015 |
Systematic integration of biomedical knowledge prioritizes drugs for repurposing DS Himmelstein, A Lizee, C Hessler, L Brueggeman, SL Chen, D Hadley, ... Elife 6, e26726, 2017 | 549 | 2017 |
Sci-Hub provides access to nearly all scholarly literature DS Himmelstein, AR Romero, JG Levernier, TA Munro, SR McLaughlin, ... ELife 7, e32822, 2018 | 272 | 2018 |
Heterogeneous network edge prediction: a data integration approach to prioritize disease-associated genes DS Himmelstein, SE Baranzini PLoS computational biology 11 (7), e1004259, 2015 | 190 | 2015 |
PMLB v1. 0: an open-source dataset collection for benchmarking machine learning methods JD Romano, TT Le, W La Cava, JT Gregg, DJ Goldberg, P Chakraborty, ... Bioinformatics 38 (3), 878-880, 2022 | 111 | 2022 |
Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS CS Greene, NA Sinnott-Armstrong, DS Himmelstein, PJ Park, JH Moore, ... Bioinformatics 26 (5), 694-695, 2010 | 105 | 2010 |
Association of HLA genetic risk burden with disease phenotypes in multiple sclerosis N Isobe, A Keshavan, PA Gourraud, AH Zhu, E Datta, R Schlaeger, ... JAMA neurology 73 (7), 795-802, 2016 | 102 | 2016 |
Mondo: Unifying diseases for the world, by the world NA Vasilevsky, NA Matentzoglu, S Toro, JE Flack IV, H Hegde, DR Unni, ... MedRxiv, 2022.04. 13.22273750, 2022 | 84 | 2022 |
Compressing gene expression data using multiple latent space dimensionalities learns complementary biological representations GP Way, M Zietz, V Rubinetti, DS Himmelstein, CS Greene Genome biology 21, 1-27, 2020 | 71 | 2020 |
Is authorship sufficient for today’s collaborative research? A call for contributor roles NA Vasilevsky, M Hosseini, S Teplitzky, V Ilik, E Mohammadi, J Schneider, ... Accountability in Research 28 (1), 23-43, 2021 | 69 | 2021 |
Open collaborative writing with Manubot DS Himmelstein, V Rubinetti, DR Slochower, D Hu, VS Malladi, ... PLoS computational biology 15 (6), e1007128, 2019 | 68 | 2019 |
Enabling personal genomics with an explicit test of epistasis CS Greene, DS Himmelstein, HH Nelson, K T KELSEY, SM Williams, ... Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 327, 2010 | 59 | 2010 |
The informative extremes: using both nearest and farthest individuals can improve relief algorithms in the domain of human genetics CS Greene, DS Himmelstein, J Kiralis, JH Moore European conference on evolutionary computation, machine learning and data …, 2010 | 51 | 2010 |
Lung cancer incidence decreases with elevation: evidence for oxygen as an inhaled carcinogen KP Simeonov, DS Himmelstein PeerJ 3, e705, 2015 | 48 | 2015 |
Precision annotation of digital samples in NCBI’s gene expression omnibus D Hadley, J Pan, O El-Sayed, J Aljabban, I Aljabban, TD Azad, ... Scientific data 4 (1), 1-11, 2017 | 47 | 2017 |
Johnny Israeli, Jack Lanchantin, Stephen Woloszynek, Anne E T Ching, DS Himmelstein, BK Beaulieu-Jones, AA Kalinin, BT Do, ... Carpenter, Avanti Shrikumar, Jinbo Xu, Evan M. Cofer, Christopher A …, 2018 | 43 | 2018 |
iCTNet2: integrating heterogeneous biological interactions to understand complex traits L Wang, DS Himmelstein, A Santaniello, M Parvin, SE Baranzini F1000Research 4, 2015 | 35* | 2015 |
Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis P Khankhanian, W Cozen, DS Himmelstein, L Madireddy, L Din, ... International Journal of Epidemiology 45 (3), 728-740, 2016 | 34 | 2016 |
Unifying the identification of biomedical entities with the Bioregistry CT Hoyt, M Balk, TJ Callahan, D Domingo-Fernández, MA Haendel, ... Scientific data 9 (1), 714, 2022 | 28 | 2022 |