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SOX9 is required for maintenance of the pancreatic progenitor cell pool PA Seymour, KK Freude, MN Tran, EE Mayes, J Jensen, R Kist, G Scherer, ... Proceedings of the National Academy of Sciences 104 (6), 1865-1870, 2007 | 715 | 2007 |
Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas M Sander, L Sussel, J Conners, D Scheel, J Kalamaras, F Dela Cruz, ... Development 127 (24), 5533-5540, 2000 | 702 | 2000 |
Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. M Sander, A Neubüser, J Kalamaras, HC Ee, GR Martin, MS German Genes & development 11 (13), 1662-1673, 1997 | 689 | 1997 |
Inactivation of specific β cell transcription factors in type 2 diabetes S Guo, C Dai, M Guo, B Taylor, JS Harmon, M Sander, RP Robertson, ... The Journal of clinical investigation 123 (8), 3305-3316, 2013 | 576 | 2013 |
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas JL Kopp, CL Dubois, AE Schaffer, E Hao, HP Shih, PA Seymour, J Ma, ... Development 138 (4), 653-665, 2011 | 559 | 2011 |
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ... Cell metabolism 16 (4), 435-448, 2012 | 500 | 2012 |
Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer J Font-Burgada, S Shalapour, S Ramaswamy, B Hsueh, D Rossell, ... Cell 162 (4), 766-779, 2015 | 494 | 2015 |
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ... Nature genetics 54 (5), 560-572, 2022 | 487 | 2022 |
The β cell transcription factors and development of the pancreas M Sander, MS German Journal of molecular medicine 75, 327-340, 1997 | 454 | 1997 |
Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling J Cai, Y Qi, X Hu, M Tan, Z Liu, J Zhang, Q Li, M Sander, M Qiu Neuron 45 (1), 41-53, 2005 | 451 | 2005 |
Pancreas organogenesis: from lineage determination to morphogenesis HP Shih, A Wang, M Sander Annual review of cell and developmental biology 29 (1), 81-105, 2013 | 406 | 2013 |
Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells BL Taylor, FF Liu, M Sander Cell reports 4 (6), 1262-1275, 2013 | 400 | 2013 |
The MafA transcription factor appears to be responsible for tissue-specific expression of insulin T Matsuoka, I Artner, E Henderson, A Means, M Sander, R Stein Proceedings of the National Academy of Sciences 101 (9), 2930-2933, 2004 | 369 | 2004 |
Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors AE Schaffer, KK Freude, SB Nelson, M Sander Developmental cell 18 (6), 1022-1029, 2010 | 354 | 2010 |
Ventral neural patterning by Nkx homeobox genes: Nkx6. 1 controls somatic motor neuron and ventral interneuron fates M Sander, S Paydar, J Ericson, J Briscoe, E Berber, M German, ... Genes & development 14 (17), 2134-2139, 2000 | 352 | 2000 |
Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification A Vallstedt, J Muhr, A Pattyn, A Pierani, M Mendelsohn, M Sander, ... Neuron 31 (5), 743-755, 2001 | 327 | 2001 |
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics J Chiou, RJ Geusz, ML Okino, JY Han, M Miller, R Melton, E Beebe, ... Nature 594 (7863), 398-402, 2021 | 300 | 2021 |
Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells R Carpentier, RE Suñer, N Van Hul, JL Kopp, JB Beaudry, S Cordi, ... Gastroenterology 141 (4), 1432-1438. e4, 2011 | 299 | 2011 |
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity AE Schaffer, BL Taylor, JR Benthuysen, J Liu, F Thorel, W Yuan, Y Jiao, ... PLoS genetics 9 (1), e1003274, 2013 | 298 | 2013 |