Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activation MJ Toth, DE Matthews, RP Tracy, MJ Previs American Journal of Physiology-Endocrinology and Metabolism 288 (5), E883-E891, 2005 | 240 | 2005 |
Molecular mechanics of cardiac myosin-binding protein C in native thick filaments MJ Previs, SB Previs, J Gulick, J Robbins, DM Warshaw Science 337 (6099), 1215-1218, 2012 | 219 | 2012 |
Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism JY Mun, MJ Previs, HY Yu, J Gulick, LS Tobacman, S Beck Previs, ... Proceedings of the National Academy of Sciences 111 (6), 2170-2175, 2014 | 173 | 2014 |
Age-related slowing of myosin actin cross-bridge kinetics is sex specific and predicts decrements in whole skeletal muscle performance in humans MS Miller, NG Bedrin, DM Callahan, MJ Previs, ME Jennings, PA Ades, ... Journal of applied physiology 115 (7), 1004-1014, 2013 | 150 | 2013 |
Phosphorylation and calcium antagonistically tune myosin-binding protein C’s structure and function MJ Previs, JY Mun, AJ Michalek, SB Previs, J Gulick, J Robbins, ... Proceedings of the National Academy of Sciences 113 (12), 3239-3244, 2016 | 115 | 2016 |
Omecamtiv mecarbil enhances the duty ratio of human β-cardiac myosin resulting in increased calcium sensitivity and slowed force development in cardiac muscle AM Swenson, W Tang, CA Blair, CM Fetrow, WC Unrath, MJ Previs, ... Journal of Biological Chemistry 292 (9), 3768-3778, 2017 | 103 | 2017 |
Unique single molecule binding of cardiac myosin binding protein-C to actin and phosphorylation-dependent inhibition of actomyosin motility requires 17 amino acids of the motif … A Weith, S Sadayappan, J Gulick, MJ Previs, P VanBuren, J Robbins, ... Journal of molecular and cellular cardiology 52 (1), 219-227, 2012 | 100 | 2012 |
Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling MJ Previs, BL Prosser, JY Mun, SB Previs, J Gulick, K Lee, J Robbins, ... Science advances 1 (1), e1400205, 2015 | 91 | 2015 |
Effects of MYBPC3 loss-of-function mutations preceding hypertrophic cardiomyopathy AS Helms, VT Tang, TS O’Leary, S Friedline, M Wauchope, A Arora, ... JCI insight 5 (2), 2020 | 83 | 2020 |
Measuring proteome dynamics in vivo: as easy as adding water? N Rachdaoui, L Austin, E Kramer, MJ Previs, VE Anderson, T Kasumov, ... Molecular & Cellular Proteomics 8 (12), 2653-2663, 2009 | 80 | 2009 |
MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy TS O'Leary, J Snyder, S Sadayappan, SM Day, MJ Previs Journal of molecular and cellular cardiology 127, 165-173, 2019 | 65 | 2019 |
Revealing the mechanism of how cardiac myosin-binding protein C N-terminal fragments sensitize thin filaments for myosin binding AV Inchingolo, SB Previs, MJ Previs, DM Warshaw, NM Kad Proceedings of the National Academy of Sciences 116 (14), 6828-6835, 2019 | 62 | 2019 |
Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism J Robert-Paganin, JP Robblee, D Auguin, TCA Blake, CS Bookwalter, ... Nature Communications 10 (1), 3286, 2019 | 61 | 2019 |
Skeletal muscle myofibrillar protein metabolism in heart failure: relationship to immune activation and functional capacity MJ Toth, DE Matthews, PA Ades, MD Tischler, P Van Buren, M Previs, ... American Journal of Physiology-Endocrinology and Metabolism 288 (4), E685-E692, 2005 | 52 | 2005 |
Defects in the proteome and metabolome in human hypertrophic cardiomyopathy MJ Previs, TS O’Leary, MP Morley, BM Palmer, M LeWinter, JM Yob, ... Circulation: Heart Failure 15 (6), e009521, 2022 | 51 | 2022 |
The extent of cardiac myosin binding protein-C phosphorylation modulates actomyosin function in a graded manner AE Weith, MJ Previs, GJ Hoeprich, SB Previs, J Gulick, J Robbins, ... Journal of muscle research and cell motility 33, 449-459, 2012 | 50 | 2012 |
Roles for cardiac MyBP-C in maintaining myofilament lattice rigidity and prolonging myosin cross-bridge lifetime BM Palmer, S Sadayappan, Y Wang, AE Weith, MJ Previs, T Bekyarova, ... Biophysical journal 101 (7), 1661-1669, 2011 | 49 | 2011 |
Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner BL Lin, A Li, JY Mun, MJ Previs, SB Previs, SG Campbell, ... Scientific reports 8 (1), 2604, 2018 | 48 | 2018 |
Regulation of fission yeast myosin-II function and contractile ring dynamics by regulatory light-chain and heavy-chain phosphorylation TE Sladewski, MJ Previs, M Lord Molecular biology of the cell 20 (17), 3941-3952, 2009 | 47 | 2009 |
The N terminus of myosin-binding protein C extends toward actin filaments in intact cardiac muscle S Rahmanseresht, KH Lee, TS O’Leary, JW McNamara, S Sadayappan, ... Journal of General Physiology 153 (3), e202012726, 2021 | 43 | 2021 |