Recruitment of Nck by CD3ϵ reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation D Gil, WWA Schamel, M Montoya, F Sánchez-Madrid, B Alarcón Cell 109 (7), 901-912, 2002 | 587 | 2002 |
Initiation of TCR signaling: regulation within CD3 dimers B Alarcón, D Gil, P Delgado, WWA Schamel Immunological reviews 191 (1), 38-46, 2003 | 183 | 2003 |
T cell receptor engagement by peptide–MHC ligands induces a conformational change in the CD3 complex of thymocytes D Gil, AG Schrum, B Alarcón, E Palmer The Journal of experimental medicine 201 (4), 517-522, 2005 | 159 | 2005 |
Ligand-induced conformational change in the T-cell receptor associated with productive immune synapses RM Risueño, D Gil, E Fernández, F Sánchez-Madrid, B Alarcón Blood 106 (2), 601-608, 2005 | 96 | 2005 |
The CD3ε proline-rich sequence, and its interaction with Nck, is not required for T cell development and function AL Szymczak, CJ Workman, D Gil, S Dilioglou, KM Vignali, E Palmer, ... The Journal of Immunology 175 (1), 270-275, 2005 | 93 | 2005 |
Strategies to stabilize compact folding and minimize aggregation of antibody-based fragments D Gil, AG Schrum Advances in bioscience and biotechnology (Print) 4 (4a), 73, 2013 | 87 | 2013 |
Analysis of the CD33-related siglec family reveals that Siglec-9 is an endocytic receptor expressed on subsets of acute myeloid leukemia cells and absent from normal … B Biedermann, D Gil, DT Bowen, PR Crocker Leukemia research 31 (2), 211-220, 2007 | 82 | 2007 |
End‐binding protein 1 controls signal propagation from the T cell receptor NB Martín‐Cófreces, F Baixauli, MJ López, D Gil, A Monjas, B Alarcón, ... The EMBO journal 31 (21), 4140-4152, 2012 | 78 | 2012 |
High-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry AG Schrum, D Gil, EP Dopfer, DL Wiest, LA Turka, WWA Schamel, ... Science's STKE 2007 (389), pl2-pl2, 2007 | 58 | 2007 |
Rho regulates T cell receptor ITAM‐induced lymphocyte spreading in an integrin‐independent manner A Borroto, D Gil, P Delgado, M Vicente‐Manzanares, A Alcover, ... European journal of immunology 30 (12), 3403-3410, 2000 | 58 | 2000 |
TCR engagement induces proline-rich tyrosine kinase-2 (Pyk2) translocation to the T cell-APC interface independently of Pyk2 activity and in an immunoreceptor tyrosine-based … D Sancho, MC Montoya, A Monjas, M Gordón-Alonso, T Katagiri, D Gil, ... The Journal of Immunology 169 (1), 292-300, 2002 | 55 | 2002 |
IL-12 signals through the TCR to support CD8 innate immune responses NP Goplen, V Saxena, KM Knudson, AG Schrum, D Gil, MA Daniels, ... The Journal of Immunology 197 (6), 2434-2443, 2016 | 41 | 2016 |
Intracellular redistribution of nucleolin upon interaction with the CD3ε chain of the T cell receptor complex D Gil, D Gutiérrez, B Alarcón Journal of Biological Chemistry 276 (14), 11174-11179, 2001 | 37 | 2001 |
Basal and antigen-induced exposure of the proline-rich sequence in CD3ε J De La Cruz, T Kruger, CA Parks, RL Silge, NSC Van Oers, IF Luescher, ... The Journal of Immunology 186 (4), 2282-2290, 2011 | 32 | 2011 |
Multiplex matrix network analysis of protein complexes in the human TCR signalosome SEP Smith, SC Neier, BK Reed, TR Davis, JP Sinnwell, JE Eckel-Passow, ... Science signaling 9 (439), rs7-rs7, 2016 | 31 | 2016 |
A role for CD8 in the developmental tuning of antigen recognition and CD3 conformational change D Gil, AG Schrum, MA Daniels, E Palmer The Journal of Immunology 180 (6), 3900-3909, 2008 | 28 | 2008 |
Three-Dimensional Model of Sub-Plasmalemmal Ca2+ Microdomains Evoked by the Interplay Between ORAI1 and InsP3 Receptors D Gil, AH Guse, G Dupont Frontiers in immunology 12, 659790, 2021 | 26 | 2021 |
IgG Fab fragments forming bivalent complexes by a conformational mechanism that is reversible by osmolytes AD Nelson, MM Hoffmann, CA Parks, S Dasari, AG Schrum, D Gil Journal of Biological Chemistry 287 (51), 42936-42950, 2012 | 20 | 2012 |
STING controls T cell memory fitness during infection through T cell-intrinsic and IDO-dependent mechanisms MJ Quaney, CJ Pritzl, D Luera, RJ Newth, KM Knudson, V Saxena, ... Proceedings of the National Academy of Sciences 120 (3), e2205049120, 2023 | 19 | 2023 |
IP-FCM measures physiologic protein-protein interactions modulated by signal transduction and small-molecule drug inhibition SEP Smith, AT Bida, TR Davis, H Sicotte, SE Patterson, D Gil, AG Schrum Public Library of Science 7 (9), e45722, 2012 | 19 | 2012 |