フォロー
Egyed Attila
Egyed Attila
Research Centre for Natural Sciences
確認したメール アドレス: ttk.hu
タイトル
引用先
引用先
An electrophilic warhead library for mapping the reactivity and accessibility of tractable cysteines in protein kinases
L Petri, A Egyed, D Bajusz, T Imre, A Hetényi, T Martinek, ...
European Journal of Medicinal Chemistry 207, 112836, 2020
362020
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
S Prokop, P Ábrányi-Balogh, B Barti, M Vámosi, M Zöldi, L Barna, ...
Nature Communications 12 (1), 6505, 2021
342021
The impact of the secondary binding pocket on the pharmacology of class A GPCRs
A Egyed, DJ Kiss, GM Keserű
Frontiers in pharmacology 13, 847788, 2022
192022
Controlling receptor function from the extracellular vestibule of G-protein coupled receptors
A Egyed, K Domány-Kovács, B Koványi, F Horti, D Kurkó, DJ Kiss, ...
Chemical Communications 56 (91), 14167-14170, 2020
162020
Discovery of a novel kinase hinge binder fragment by dynamic undocking
M Rachman, D Bajusz, A Hetényi, A Scarpino, B Merő, A Egyed, L Buday, ...
RSC Medicinal Chemistry 11 (5), 552-558, 2020
132020
Controlling the selectivity of aminergic GPCR ligands from the extracellular vestibule
A Egyed, ÁA Kelemen, M Vass, A Visegrády, SA Thee, Z Wang, ...
Bioorganic Chemistry 111, 104832, 2021
122021
The impact of binding site waters on the activity/selectivity trade-off of Janus kinase 2 (JAK2) inhibitors
A Egyed, D Bajusz, GM Keserű
Bioorganic & Medicinal Chemistry 27 (8), 1497-1508, 2019
52019
Safe and Efficient Continuous-Flow Synthesis and Batchwise Hydrolysis of Ethyl 5-Acetyl-1H-pyrazole-3-carboxylate: A Key Synthon of Darolutamide
B Szilágyi, A Egyed, I Mándity, T Nagy, K Kátai-Fadgyas, B Volk, ...
Synthesis 55 (06), 959-966, 2023
32023
Progress on the development of Class A GPCR‐biased ligands
P Morales, MM Scharf, M Bermudez, A Egyed, R Franco, OK Hansen, ...
British Journal of Pharmacology, 2024
22024
Development of a silicone-based polymer matrix as a suitable Transdermal Therapeutic System for diallyl disulfide
S László, Z Hajna, A Egyed, E Pintér, Ö Wagner
Pharmaceuticals 15 (10), 1182, 2022
22022
The Polypharmacology of Cariprazine and its Implications to Clinical Indications
A Egyed, DJ Kiss, GM Keserű
Polypharmacology: Strategies for Multi‐Target Drug Discovery, 385-404, 2025
2025
Contribution of Noncovalent Recognition and Reactivity to the Optimization of Covalent Inhibitors: A Case Study on KRasG12C
N Péczka, I Ranđelović, Z Orgován, N Csorba, A Egyed, L Petri, ...
ACS Chemical Biology 19 (8), 1743-1756, 2024
2024
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