| Progress in the medicinal chemistry of silicon: C/Si exchange and beyond S Fujii, Y Hashimoto Future Medicinal Chemistry 9 (5), 485-505, 2017 | 134 | 2017 |
| Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane S Fujii, H Masuno, Y Taoda, A Kano, A Wongmayura, M Nakabayashi, ... Journal of the American Chemical Society 133 (51), 20933-20941, 2011 | 111 | 2011 |
| Increased hydrophobicity and estrogenic activity of simple phenols with silicon and germanium-containing substituents S Fujii, Y Miyajima, H Masuno, H Kagechika Journal of Medicinal Chemistry 56 (1), 160-166, 2013 | 101 | 2013 |
| Potent androgen antagonists based on carborane as a hydrophobic core structure S Fujii, T Goto, K Ohta, Y Hashimoto, T Suzuki, S Ohta, Y Endo Journal of medicinal chemistry 48 (14), 4654-4662, 2005 | 98 | 2005 |
| Discovery of novel SPAK inhibitors that block WNK kinase signaling to cation chloride transporters E Kikuchi, T Mori, M Zeniya, K Isobe, M Ishigami-Yuasa, S Fujii, ... Journal of the American Society of Nephrology 26 (7), 1525-1536, 2015 | 87 | 2015 |
| Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy T Mori, E Kikuchi, Y Watanabe, S Fujii, M Ishigami-Yuasa, H Kagechika, ... Biochemical Journal 455 (3), 339-345, 2013 | 76 | 2013 |
| A new class of androgen receptor antagonists bearing carborane in place of a steroidal skeleton S Fujii, Y Hashimoto, T Suzuki, S Ohta, Y Endo Bioorganic & medicinal chemistry letters 15 (1), 227-230, 2005 | 60 | 2005 |
| Design and Synthesis of Androgen Receptor Full Antagonists Bearing a p-Carborane Cage: Promising Ligands for Anti-Androgen Withdrawal Syndrome T Goto, K Ohta, S Fujii, S Ohta, Y Endo Journal of medicinal chemistry 53 (13), 4917-4926, 2010 | 53 | 2010 |
| Expanding the chemical space of hydrophobic pharmacophores: the role of hydrophobic substructures in the development of novel transcription modulators S Fujii MedChemComm 7 (6), 1082-1092, 2016 | 45 | 2016 |
| Development of novel AKR1C3 inhibitors as new potential treatment for castration-resistant prostate cancer S Endo, H Oguri, J Segawa, M Kawai, D Hu, S Xia, T Okada, K Irie, S Fujii, ... Journal of medicinal chemistry 63 (18), 10396-10411, 2020 | 44 | 2020 |
| Systematic synthesis and anti-inflammatory activity of ω-carboxylated menaquinone derivatives—Investigations on identified and putative vitamin K2 metabolites S Fujii, A Shimizu, N Takeda, K Oguchi, T Katsurai, H Shirakawa, ... Bioorganic & Medicinal Chemistry 23 (10), 2344-2352, 2015 | 43 | 2015 |
| Acidic heterocycles as novel hydrophilic pharmacophore of androgen receptor ligands with a carborane core structure S Fujii, K Ohta, T Goto, H Kagechika, Y Endo Bioorganic & medicinal chemistry 17 (1), 344-350, 2009 | 42 | 2009 |
| 6-Arylcoumarins as novel nonsteroidal type progesterone antagonists: an example with receptor-binding-dependent fluorescence H Sakai, T Hirano, S Mori, S Fujii, H Masuno, M Kinoshita, H Kagechika, ... Journal of medicinal chemistry 54 (20), 7055-7065, 2011 | 37 | 2011 |
| Design and synthesis of nonsteroidal progesterone receptor antagonists based on C, C′-diphenylcarborane scaffold as a hydrophobic pharmacophore S Fujii, A Yamada, E Nakano, Y Takeuchi, S Mori, H Masuno, ... European journal of medicinal chemistry 84, 264-277, 2014 | 36 | 2014 |
| Androgen receptor modulators: a review of recent patents and reports (2012-2018) S Fujii, H Kagechika Expert opinion on therapeutic patents 29 (6), 439-453, 2019 | 34 | 2019 |
| Future Med. Chem. 2017, 9, 485. c) R. Ramesh, DS Reddy S Fujii, Y Hashimoto J. Med. Chem 61, 3779, 2018 | 34 | 2018 |
| Structural development of p-carborane-based potent non-secosteroidal vitamin D analogs S Fujii, R Sekine, A Kano, H Masuno, C Songkram, E Kawachi, T Hirano, ... Bioorganic & Medicinal Chemistry 22 (21), 5891-5901, 2014 | 32 | 2014 |
| Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists K Inoue, K Urushibara, M Kanai, K Yura, S Fujii, M Ishigami-Yuasa, ... European Journal of Medicinal Chemistry 102, 310-319, 2015 | 31 | 2015 |
| Copper‐Mediated CC Cross‐Coupling Reaction of Monocarba‐closo‐dodecaborate Anion for the Synthesis of Functional Molecules J Kanazawa, R Takita, A Jankowiak, S Fujii, H Kagechika, D Hashizume, ... Angewandte Chemie 125 (31), 8175-8179, 2013 | 31 | 2013 |
| Crystal structure, docking study and structure–activity relationship of carborane-containing androgen receptor antagonist 3-(12-hydroxymethyl-1, 12-dicarba-closo-dodecaboran-1 … K Ohta, T Goto, S Fujii, M Kawahata, A Oda, S Ohta, K Yamaguchi, ... Bioorganic & medicinal chemistry 19 (11), 3540-3548, 2011 | 30 | 2011 |
Isao AzumayaFaculty of Pharmaceutical Sciences, Toho University確認したメール アドレス: phar.toho-u.ac.jp