Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase TA Rosenquist, DO Zharkov, AP Grollman Proceedings of the National Academy of Sciences 94 (14), 7429-7434, 1997 | 620 | 1997 |
Base excision DNA repair DO Zharkov Cellular and molecular life sciences 65, 1544-1565, 2008 | 406 | 2008 |
Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA R Gilboa, DO Zharkov, G Golan, AS Fernandes, SE Gerchman, E Matz, ... Journal of Biological Chemistry 277 (22), 19811-19816, 2002 | 318 | 2002 |
Substrate specificity and reaction mechanism of murine 8-oxoguanine-DNA glycosylase DO Zharkov, TA Rosenquist, SE Gerchman, AP Grollman Journal of Biological Chemistry 275 (37), 28607-28617, 2000 | 236 | 2000 |
The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death TA Rosenquist, E Zaika, AS Fernandes, DO Zharkov, H Miller, ... DNA repair 2 (5), 581-591, 2003 | 227 | 2003 |
NH2-terminal proline acts as a nucleophile in the glycosylase/AP-lyase reaction catalyzed by Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg) protein DO Zharkov, RA Rieger, CR Iden, AP Grollman Journal of Biological Chemistry 272 (8), 5335-5341, 1997 | 226 | 1997 |
Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate DO Zharkov, G Golan, R Gilboa, AS Fernandes, SE Gerchman, JH Kycia, ... The EMBO journal, 2002 | 205 | 2002 |
Structural characterization of the Fpg family of DNA glycosylases DO Zharkov, G Shoham, AP Grollman DNA repair 2 (8), 839-862, 2003 | 180 | 2003 |
Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase NA Kuznetsov, VV Koval, DO Zharkov, GA Nevinsky, KT Douglas, ... Nucleic acids research 33 (12), 3919-3931, 2005 | 138 | 2005 |
Mechanism of interaction between human 8-oxoguanine-DNA glycosylase and AP endonuclease VS Sidorenko, GA Nevinsky, DO Zharkov DNA repair 6 (3), 317-328, 2007 | 137 | 2007 |
Uracil-DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognition DO Zharkov, GV Mechetin, GA Nevinsky Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 685 (1 …, 2010 | 134 | 2010 |
MutY DNA glycosylase: base release and intermediate complex formation DO Zharkov, AP Grollman Biochemistry 37 (36), 12384-12394, 1998 | 118 | 1998 |
The DNA trackwalkers: principles of lesion search and recognition by DNA glycosylases DO Zharkov, AP Grollman Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 577 (1 …, 2005 | 113 | 2005 |
Inactivation of mammalian 8-oxoguanine-DNA glycosylase by cadmium (II): implications for cadmium genotoxicity DO Zharkov, TA Rosenquist DNA repair 1 (8), 661-670, 2002 | 93 | 2002 |
Substrate discrimination by formamidopyrimidine-DNA glycosylase: a mutational analysis EI Zaika, RA Perlow, E Matz, S Broyde, R Gilboa, AP Grollman, ... Journal of Biological Chemistry 279 (6), 4849-4861, 2004 | 90 | 2004 |
Kinetic conformational analysis of human 8-oxoguanine-DNA glycosylase NA Kuznetsov, VV Koval, GA Nevinsky, KT Douglas, DO Zharkov, ... Journal of Biological Chemistry 282 (2), 1029-1038, 2007 | 88 | 2007 |
Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells P Prorok, D Alili, C Saint-Pierre, D Gasparutto, DO Zharkov, AA Ishchenko, ... Proceedings of the National Academy of Sciences 110 (39), E3695-E3703, 2013 | 85 | 2013 |
NEIL1 excises 3′ end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1 JL Parsons, DO Zharkov, GL Dianov Nucleic acids research 33 (15), 4849-4856, 2005 | 84 | 2005 |
Eukaryotic ribosomal protein S3: A constituent of translational machinery and an extraribosomal player in various cellular processes D Graifer, A Malygin, DO Zharkov, G Karpova Biochimie 99, 8-18, 2014 | 73 | 2014 |
Substrate discrimination by formamidopyrimidine-DNA glycosylase: distinguishing interactions within the active site RA Perlow-Poehnelt, DO Zharkov, AP Grollman, S Broyde Biochemistry 43 (51), 16092-16105, 2004 | 72 | 2004 |