Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking M Larance, G Ramm, J Stöckli, EM van Dam, S Winata, V Wasinger, ... Journal of biological chemistry 280 (45), 37803-37813, 2005 | 494 | 2005 |
Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2 SJ Humphrey, G Yang, P Yang, DJ Fazakerley, J Stöckli, JY Yang, ... Cell metabolism 17 (6), 1009-1020, 2013 | 458 | 2013 |
The aetiology and molecular landscape of insulin resistance DE James, J Stöckli, MJ Birnbaum Nature Reviews Molecular Cell Biology, 1-21, 2021 | 449 | 2021 |
Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ... Cell metabolism 22 (5), 922-935, 2015 | 436 | 2015 |
GLUT4 exocytosis J Stöckli, DJ Fazakerley, DE James J Cell Sci 124 (24), 4147-4159, 2011 | 372 | 2011 |
A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets Z Li, RJ Schulze, SG Weller, EW Krueger, MB Schott, X Zhang, CA Casey, ... Science Advances 2 (12), e1601470, 2016 | 160 | 2016 |
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ... Journal of Biological Chemistry, jbc. RA117. 001254, 2018 | 142 | 2018 |
mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes AY Minard, SX Tan, P Yang, DJ Fazakerley, W Domanova, BL Parker, ... Cell Reports 17 (1), 29-36, 2016 | 128 | 2016 |
Selective Insulin resistance in adipocytes SX Tan, KH Fisher-Wellman, DJ Fazakerley, Y Ng, H Pant, J Li, CC Meoli, ... Journal of Biological Chemistry 290 (18), 11337-11348, 2015 | 124 | 2015 |
Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects KT Tonks, Y Ng, S Miller, ACF Coster, D Samocha-Bonet, TJ Iseli, A Xu, ... Diabetologia 56 (4), 875-885, 2013 | 124 | 2013 |
High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice. JG Burchfield, MA Kebede, CC Meoli, J Stöckli, PT Whitworth, AL Wright, ... Journal of Biological Chemistry, jbc. RA117. 000808, 2018 | 96 | 2018 |
Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes DJ Fazakerley, GD Holman, A Marley, DE James, J Stöckli, ACF Coster Journal of Biological Chemistry 285 (3), 1653-1660, 2010 | 95 | 2010 |
The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 … SX Tan, Y Ng, JG Burchfield, G Ramm, DG Lambright, J Stöckli, ... Molecular and cellular biology 32 (24), 4946-4959, 2012 | 88 | 2012 |
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes SX Tan, Y Ng, CC Meoli, A Kumar, PS Khoo, DJ Fazakerley, JR Junutula, ... Journal of Biological Chemistry 287 (9), 6128-6138, 2012 | 84 | 2012 |
Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association J Stöckli, JR Davey, C Hohnen-Behrens, A Xu, DE James, G Ramm Molecular endocrinology 22 (12), 2703-2715, 2008 | 84 | 2008 |
The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle J Stöckli, CC Meoli, NJ Hoffman, DJ Fazakerley, H Pant, ME Cleasby, ... Diabetes 64 (6), 1914-1922, 2015 | 77 | 2015 |
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from … C Handschin, M Podvinec, J Stöckli, K Hoffmann, UA Meyer Molecular Endocrinology 15 (9), 1571-1585, 2001 | 68 | 2001 |
Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway S Trefely, PS Khoo, JR Krycer, R Chaudhuri, DJ Fazakerley, BL Parker, ... Journal of Biological Chemistry 290 (43), 25834-25846, 2015 | 67 | 2015 |
Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes DJ Fazakerley, S Naghiloo, R Chaudhuri, F Koumanov, JG Burchfield, ... Journal of Biological Chemistry 290 (39), 23528-23542, 2015 | 65 | 2015 |
Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry ME Nelson, BL Parker, JG Burchfield, NJ Hoffman, EJ Needham, ... The EMBO journal, 2019 | 61 | 2019 |